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2 Biotechnology in the Age of Synthetic Biology (15-22)
3 Framework for Assessing Concern About Synthetic Biology Capabilities (23-36)
4 Assessment of Concerns Related to Pathogens (37-58)
5 Assessment of Concerns Related to Production of Chemicals or Biochemicals (59-70)
6 Assessment of Concerns Related to Bioweapons that Alter the Human Host (71-84)
7 Related Developments That May Impact the Ability to Effect an Attack Using a Synthetic BiologyEnabled Weapon (85-94)
8 Options for Mitigating Concerns (95-114)
9 Moving Forward: Conclusions and Recommendations (115-128)
Appendix A: Specific Synthetic Biology Concepts, Approaches, and Tools (147-156)
Appendix B: Selected Prior Analyses Used to Inform the Framework (157-162)
Appendix C: Questions to Stimulate Consideration of Framework Factors (163-166)
Appendix D: Committee Biographies (167-170)
Appendix E: Disclosure of Conflict of Interest (171-172)