This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.
National Research Council. 1989. Immunodeficient Rodents: A Guide to Their Immunobiology, Husbandry, and Use. Washington, DC: The National Academies Press. https://doi.org/10.17226/1051.
|2 HEREDITARY IMMUNODEFICIENCIES
|3 INDUCED IMMUNODEFICIENCIES
|4 MAINTENANCE OF RODENTS REQUIRING ISOLATION
|5 MATING SYSTEMS FOR MUTANTS
|6 GENETIC MECHANISMS GOVERNING RESISTANCE OR SUSCEPTIBILITY . . .
|APPENDIX: HEMATOPOIETIC CELL-SURFACE ANTIGENS MENTIONED IN THE TEXT
The Chapter Skim search tool presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter. You may select key terms to highlight them within pages of each chapter.
The National Academies Press (NAP) has partnered with Copyright Clearance Center's Marketplace service to offer you a variety of options for reusing NAP content. Through Marketplace, you may request permission to reprint NAP content in another publication, course pack, secure website, or other media. Marketplace allows you to instantly obtain permission, pay related fees, and print a license directly from the NAP website. The complete terms and conditions of your reuse license can be found in the license agreement that will be made available to you during the online order process. To request permission through Marketplace you are required to create an account by filling out a simple online form. The following list describes license reuses offered by the NAP through Marketplace:
Click here to obtain permission for the above reuses. If you have questions or comments concerning the Marketplace service, please contact:
US Toll Free +1.855.239.3415
To request permission to distribute a PDF, please contact our Customer Service Department at firstname.lastname@example.org.