Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program

Institute of Medicine

doi:10.17226/11269

Consensus Study Report

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Cord Blood

Establishing a National Hematopoietic Stem Cell Bank Program

(2005)

With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines:

The role of cord blood in stem cell transplantation
The current status of blood banks already in existence
The optimal structure for the cord blood program
The current use and utility of cord blood for stem cell transplants
The best way to advance the use of cord blood units and make them available for research

Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders.

Contributor(s): Institute of Medicine; Board on Health Sciences Policy; Committee on Establishing a National Cord Blood Stem Cell Bank Program; Emily Ann Meyer, Kathi Hanna, and Kristine Gebbie, Editors

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Suggested Citation

Institute of Medicine. 2005. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program. Washington, DC: The National Academies Press. https://doi.org/10.17226/11269.

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Publication Info

334 pages | 6 x 9 |

ISBNs:

Hardcover: 978-0-309-09586-0
Ebook: 978-0-309-16517-4

DOI: https://doi.org/10.17226/11269

Chapters		skim
Front Matter	i-xx
Executive Summary	1-19
1 Introduction	20-32
2 Hematopoietic Stem Cell Transplantation	33-55
3 Research	56-74
4 Umbilical Cord Blood Banks and Banking	75-105
5 Ethical and Legal Issues	106-119
6 Inventory of a National Cord Blood Stem Cell Bank Program	120-128
7 Recommended Structure of a National Program	129-140
Appendix A: Methods Section: Data Collection and Analysis	141-148
Appendix B: Survey	149-159
Appendix C: Survey Results	160-207
Appendix D: Potential Nonhematopoietic Uses for Stem Cells in Cord Blood	208-220
Appendix E: A Cost-Benefit Analysis of Increasing Cord Blood Inventory Levels	221-241
Appendix F: HLA Overview	242-272
Appendix G: Analysis of the NYBC, NMDP, and NHLBI Cord Blood Data	273-282
Appendix H: Biographical Sketches of Committee Members and Staff	283-292
Acronyms	293-296
Glossary	297-300
Index	301-314

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