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Although the U.S. Environmental Protection Agency presented a comprehensive review of the scientific literature in its 2003 draft reassessment of the risks of dioxin, the agency did not sufficiently quantify the uncertainties and variabilities associated with the risks, nor did it adequately justify the assumptions used to estimate them, according to this new report from the National Academies' National Research Council. The committee that wrote the report recommended that EPA re-estimate the risks using several different assumptions and better communicate the uncertainties in those estimates. The agency also should explain more clearly how it selects both the data upon which the reassessment is based and the methods used to analyze them.

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Suggested Citation

National Research Council. 2006. Health Risks from Dioxin and Related Compounds: Evaluation of the EPA Reassessment. Washington, DC: The National Academies Press. https://doi.org/10.17226/11688.

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Publication Info

268 pages |  6 x 9 | 

ISBNs: 
  • Paperback:  978-0-309-10258-2
  • Ebook:  978-0-309-13388-3
DOI: https://doi.org/10.17226/11688
Chapters skim
Front Matter i-xxviii
Public Summary 1-10
Summary 11-27
1 Introduction 28-44
2 General Considerations of Uncertaintyand Variability, Selection of DoseMetric, and Dose-Response Modeling 45-74
3 Toxic Equivalency Factors 75-89
4 Exposure Assessment 90-107
5 Cancer 108-143
6 Noncancer End Points 144-174
7 Review of Risk Characterization 175-187
8 Conclusions and Recommendations 188-198
References 199-226
A Biographical Information onCommittee Members 227-235
B EPA's 2005 Guidelines forCarcinogen Risk Assessment 236-240

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