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Consensus Study Report

Suggested Citation

Institute of Medicine. 1985. New Vaccine Development: Establishing Priorities: Volume I: Diseases of Importance in the United States. Washington, DC: The National Academies Press.

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Publication Info

472 pages |  6 x 9 |  DOI:
Chapters skim
Front Matter i-xiv
1. Summary 1-16
2. Priority Setting for Health Related Investments: A Review of Methods 17-27
3. Overview of the Analytic Approach 28-38
4. Comparison of Disease Burdens and Costs 39-58
5. Predictions on Vaccine Development 59-66
6. Assessing the Likely Utilization of New Vaccines 67-91
7. Calculation and Comparison of the Health Benefits and Costs Associated with Candidate Vaccines 92-120
8. Additional Issues in the Selection of Priorities for Accelerated Vaccine Development 121-126
9. Findings, Conclusions, and Recommendations 127-148
Appendix A: Some Examples of the Application of Project Selection Method 149-152
Appendix B: Pathogenic Agents for Which Accelerated Vaccine Development Does Not Appear Appropriate 153-170
Appendix C: Prospects for Immunizing Against Bordetella pertussis 171-182
Appendix D: Prospects for Immunizing Against Coccidioidomycosis 183-197
Appendix E: Prospects for Immunizing Against Cytomegalovirus 198-234
Appendix F: Prospects for Immunizing Against Hemophilus influenzae type b 235-251
Appendix G: Prospects for Immunizing Against Hepatitis A Virus 252-260
Appendix H: Prospects for Immunizing Against Hepatitis B Virus 261-279
Appendix I: Prospects for Immunizing Against Herpes Simplex Viruses 1 and 2 280-312
Appendix J: Prospects for Immunizing Against Herpesvirus varicellae 313-341
Appendix K: Prospects for Immunizing Against Influenza Viruses A and B 342-364
Appendix L: Prospects for Immunizing Against Neisseria gonorrhoeae 365-384
Appendix M: Prospects for Immunizing Against Parainfluenza Viruses 385-396
Appendix N: Prospects for Immunizing Against Respiratory Syncytial Virus 397-409
Appendix O: Prospects for Immunizing Against Rotavirus 410-423
Appendix P: Prospects for Immunizing Against Streptococcus group B 424-439
Appendix Q: Questionnaire for Assessing Morbidity-Mortality Trade-Offs 440-443
Appendix R: Technical Notes 444-444
Appendix S: Biographical Notes on Committee Members 445-449
Appendix T: Additional Sources of Advice to the Committee 450-452
Index 453-458

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