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Biologic markers—indicators of biological exposure or change—offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicate dose or exposure levels, noninvasive respiratory function tests for use with healthy humans to detect sensitivity to inhaled pollutants, approaches to evaluating markers down to the cellular and biochemical levels, and more.

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Suggested Citation

National Research Council. 1989. Biologic Markers in Pulmonary Toxicology. Washington, DC: The National Academies Press. https://doi.org/10.17226/1216.

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Publication Info

196 pages |  7 x 10 | 

ISBNs: 
  • Paperback:  978-0-309-03990-1
  • Hardcover:  978-0-309-03992-5
DOI: https://doi.org/10.17226/1216
Chapters skim
Front Matter i-xiv
Executive Summary 1-10
1 Introduction 11-16
2 Markers of Exposure 17-42
3 Markers of Physiologic Effects in Intact Organisms 43-82
4 Markers of Altered Structure or Function 83-90
5 Markers of Inflammatory and Immune Response 91-104
6 Markers of Cellular and Biochemical Response 105-132
7 Conclusions and Recommendations 133-136
References 137-166
Biographies 167-170
Index 171-180

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