Use of the term "multiple chemical sensitivity" (MCS) as a diagnostic label has generated increasing controversy during the past few decades as a phenomenon related to exposure to chemical agents sustained both in indoor and outdoor environments.
This volume, prepared in conjunction with Biologic Markers in Immunotoxicology, contains the authored papers of a workshop held to develop an agenda to study the phenomenon of multiple chemical sensitivity. Authored by clinicians, immunologists, toxicologists, epidemiologists, psychiatrists, psychologists, and others involved in research or clinical activities relevant to the problem, the papers contain case evaluations and criteria for diagnosis, mechanisms potentially underlying MCS, and epidemiologic approaches to investigation.
National Research Council. 1992. Multiple Chemical Sensitivities: Addendum to Biologic Markers in Immunotoxicology. Washington, DC: The National Academies Press. https://doi.org/10.17226/1988.
|Research Protocol for Clinical Evaluation
|Exposures and Mechanisms
|Key Concepts: Chemical Sensitization
|Multiple Chemical Sensitivity - What is It?
|Case Definitions for Multiple Chemical Sensitivity
|Allergy and Multiple Chemical Sensitivities (MCS) Distinguished
|Design of Animal Models to Probe the Mechanisms of Multiple Chemical Sensitivity
|Antigen Specific and Antigen Non-Specific Immunization
|Neuropsychiatric and Biopsychosocial Mechanisms in Multiple Chemical Sensitivity: An Olfactory-Limbic System Model
|Neurobehavioral and Psychosocial Aspects of Multiple Chemical Sensitivity
|Diagnostic Markers of Multiple Chemical Sensitivity
|Possible Mechanisms for Multiple Chemical Sensitivity: The Limbic System and Others
|Developing Clinical Research Protocols for Studying Chemical Sensitivities
|Immunological Mechanisms of Disease and the Multiple Chemical Sensitivity Syndrome
|Considerations for the Diagnosis of Chemical Sensitivity
|List of Contributors
|List of Participants
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