Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes.
Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
National Academies of Sciences, Engineering, and Medicine. 2018. Public Health Consequences of E-Cigarettes. Washington, DC: The National Academies Press. https://doi.org/10.17226/24952.
|Summary Annex Report Conclusions by Level of Evidence||17-22|
|2 Committee Approach||43-52|
|Section I: E-Cigarette Devices, Constituents, and Exposures||53-54|
|3 E-Cigarette Devices, Uses, and Exposures||55-88|
|5 Toxicology of E-Cigarette Constituents||155-216|
|6 Research Needs: E-Cigarette Devices, Constituents, and Exposures||217-220|
|Section II: Effects of E-Cigarettes on Health||221-222|
|7 Modes of Action||223-254|
|8 Dependence and Abuse Liability||255-338|
|9 Cardiovascular Disease||339-380|
|11 Respiratory Diseases||405-454|
|12 Oral Diseases||455-460|
|13 Developmental and Reproductive Effects||461-472|
|14 Injuries and Poisonings||473-480|
|15 Research Needs: Effects of E-Cigarettes on Health||481-486|
|Section III: Public Health Implications of E-Cigarettes||487-492|
|16 Combustible Tobacco Cigarette Smoking Among Youth and Young Adults||493-540|
|17 Smoking Cessation Among Adults||541-588|
|18 Harm Reduction||589-630|
|19 Modeling of E-Cigarette Use||631-652|
|20 Research Needs: Public Health Implications of E-Cigarettes||653-656|
|21 Concluding Observations||657-660|
|Appendix A: Questions from the Center for Tobacco Products of the Food and Drug Administration Submitted for the Committee's Consideration||661-664|
|Appendix B: Search Strategy and Quality Assessment||665-696|
|Appendix C: Glossary of Terms Related to E-Cigarettes||697-702|
|Appendix D: Cytotoxicity Tables||703-740|
|Appendix E: Public Meeting Agenda||741-744|
|Appendix F: Committee Biosketches||745-750|
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