Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response: Lessons from COVID-19

National Academies of Sciences, Engineering, and Medicine and National Academy of Medicine

doi:10.17226/26282

Consensus Study Report

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Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response

Lessons from COVID-19

(2022)

The global response to COVID-19 has demonstrated the importance of vigilance and preparedness for infectious diseases, particularly influenza. There is a need for more effective influenza vaccines and modern manufacturing technologies that are adaptable and scalable to meet demand during a pandemic. The rapid development of COVID-19 vaccines has demonstrated what is possible with extensive data sharing, researchers who have the necessary resources and novel technologies to conduct and apply their research, rolling review by regulators, and public-private partnerships. As demonstrated throughout the response to COVID-19, the process of research and development of novel vaccines can be significantly optimized when stakeholders are provided with the resources and technologies needed to support their response.

Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response focuses on how to leverage the knowledge gained from the COVID-19 pandemic to optimize vaccine research and development (R&D) to support the prevention and control of seasonal and pandemic influenza. The committee's findings address four dimensions of vaccine R&D: (1) basic and translational science, (2) clinical science, (3) manufacturing science, and (4) regulatory science.

Contributor(s): National Academies of Sciences, Engineering, and Medicine; National Academy of Medicine; Health and Medicine Division; Board on Global Health; Committee on Vaccine Research and Development Recommendations for Advancing Pandemic and Seasonal Influenza Preparedness and Response; Enriqueta Bond, Kanta Subbarao, and Hoda Soltani, Editors

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National Academies of Sciences, Engineering, and Medicine and National Academy of Medicine. 2022. Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response: Lessons from COVID-19. Washington, DC: The National Academies Press. https://doi.org/10.17226/26282.

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Publication Info

178 pages | 6 x 9 |

ISBNs:

Paperback: 978-0-309-08781-0
Ebook: 978-0-309-08785-8

DOI: https://doi.org/10.17226/26282

Chapters		skim
Front Matter	i-xxiv
Summary	1-10
1 Introduction	11-36
2 Basic and Translational Science	37-62
3 Clinical Science	63-80
4 Manufacturing Science	81-106
5 Regulatory Science	107-118
6 A Blueprint for Action	119-130
Appendix A: Committee Biographies	131-136
Appendix B: Disclosure of Unavoidable Conflict of Interest	137-138
Appendix C: Staff and Consultant Biographies	139-142
Appendix D: Public Meeting Agendas	143-154

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