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The microbial communities that reside within the human gut have profound effects on our health. Recent research has revealed that their sphere of influence extends well beyond their long-recognized role in digestion and nutrient absorption to include interactions with the immune system, the brain, and other systems. New biotechnologies are tapping into interconnections with commensal microbes along the gut-brain axis, opening exciting opportunities to prevent and treat neurological and other disorders, discover new therapeutic modalities, and improve health throughout the lifespan.
The National Academies of Sciences, Engineering, and Medicine hosted a workshop on Interactions of Biotechnology with Human Physiology and Function on December 15-16, 2022, organized under the auspices of the National Academies Standing Committee on Biotechnology Capabilities and National Security Needs. Presenters and attendees from government, academia, and industry gathered for discussions and presentations addressing recent research into the connections and mediators along the gut-brain axis, key challenges and limitations in this research, transdisciplinary technologies being pursued for potential applications, and a vision for future developments in this field. This Proceedings of a Workshop-in Brief provides a high-level overview of the event.
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