%0 Book %A National Academies of Sciences, Engineering, and Medicine %T Using 21st Century Science to Improve Risk-Related Evaluations %@ 978-0-309-45348-6 %D 2017 %U https://nap.nationalacademies.org/catalog/24635/using-21st-century-science-to-improve-risk-related-evaluations %> https://nap.nationalacademies.org/catalog/24635/using-21st-century-science-to-improve-risk-related-evaluations %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 200 %X Over the last decade, several large-scale United States and international programs have been initiated to incorporate advances in molecular and cellular biology, -omics technologies, analytical methods, bioinformatics, and computational tools and methods into the field of toxicology. Similar efforts are being pursued in the field of exposure science with the goals of obtaining more accurate and complete exposure data on individuals and populations for thousands of chemicals over the lifespan; predicting exposures from use data and chemical-property information; and translating exposures between test systems and humans. Using 21st Century Science to Improve Risk-Related Evaluations makes recommendations for integrating new scientific approaches into risk-based evaluations. This study considers the scientific advances that have occurred following the publication of the NRC reports Toxicity Testing in the 21st Century: A Vision and a Strategy and Exposure Science in the 21st Century: A Vision and a Strategy. Given the various ongoing lines of investigation and new data streams that have emerged, this publication proposes how best to integrate and use the emerging results in evaluating chemical risk. Using 21st Century Science to Improve Risk-Related Evaluations considers whether a new paradigm is needed for data validation, how to integrate the divergent data streams, how uncertainty might need to be characterized, and how best to communicate the new approaches so that they are understandable to various stakeholders. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E DeVoe, Jennifer E. %E Geller, Amy %E Negussie, Yamrot %T Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity %@ 978-0-309-49338-3 %D 2019 %U https://nap.nationalacademies.org/catalog/25466/vibrant-and-healthy-kids-aligning-science-practice-and-policy-to %> https://nap.nationalacademies.org/catalog/25466/vibrant-and-healthy-kids-aligning-science-practice-and-policy-to %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 620 %X Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Wizemann, Theresa M. %T Faith–Health Collaboration to Improve Community and Population Health: Proceedings of a Workshop %@ 978-0-309-48933-1 %D 2021 %U https://nap.nationalacademies.org/catalog/25375/faith-health-collaboration-to-improve-community-and-population-health-proceedings %> https://nap.nationalacademies.org/catalog/25375/faith-health-collaboration-to-improve-community-and-population-health-proceedings %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 74 %X On March 22, 2018, the National Academies of Sciences, Engineering, and Medicine convened a workshop to examine the collaboration between the faith and health sectors, and to highlight the unique opportunities these collaborations offer to help improve population health outcomes. This publication summarizes the presentations and discussions from the workshop. %0 Book %A National Academy of Engineering %A National Academies of Sciences, Engineering, and Medicine %T Microbiomes of the Built Environment: A Research Agenda for Indoor Microbiology, Human Health, and Buildings %@ 978-0-309-44980-9 %D 2017 %U https://nap.nationalacademies.org/catalog/23647/microbiomes-of-the-built-environment-a-research-agenda-for-indoor %> https://nap.nationalacademies.org/catalog/23647/microbiomes-of-the-built-environment-a-research-agenda-for-indoor %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Engineering and Technology %P 317 %X People's desire to understand the environments in which they live is a natural one. People spend most of their time in spaces and structures designed, built, and managed by humans, and it is estimated that people in developed countries now spend 90 percent of their lives indoors. As people move from homes to workplaces, traveling in cars and on transit systems, microorganisms are continually with and around them. The human-associated microbes that are shed, along with the human behaviors that affect their transport and removal, make significant contributions to the diversity of the indoor microbiome. The characteristics of "healthy" indoor environments cannot yet be defined, nor do microbial, clinical, and building researchers yet understand how to modify features of indoor environments—such as building ventilation systems and the chemistry of building materials—in ways that would have predictable impacts on microbial communities to promote health and prevent disease. The factors that affect the environments within buildings, the ways in which building characteristics influence the composition and function of indoor microbial communities, and the ways in which these microbial communities relate to human health and well-being are extraordinarily complex and can be explored only as a dynamic, interconnected ecosystem by engaging the fields of microbial biology and ecology, chemistry, building science, and human physiology. This report reviews what is known about the intersection of these disciplines, and how new tools may facilitate advances in understanding the ecosystem of built environments, indoor microbiomes, and effects on human health and well-being. It offers a research agenda to generate the information needed so that stakeholders with an interest in understanding the impacts of built environments will be able to make more informed decisions. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Kosti, Ourania %T Long-Term Health Monitoring of Populations Following a Nuclear or Radiological Incident in the United States: Proceedings of a Workshop %@ 978-0-309-49263-8 %D 2019 %U https://nap.nationalacademies.org/catalog/25443/long-term-health-monitoring-of-populations-following-a-nuclear-or-radiological-incident-in-the-united-states %> https://nap.nationalacademies.org/catalog/25443/long-term-health-monitoring-of-populations-following-a-nuclear-or-radiological-incident-in-the-united-states %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %K Environment and Environmental Studies %P 88 %X Accidents and terrorist attacks that lead to the release of radioactive materials can cause deaths, injuries, and a range of psychosocial effects in the surrounding community and team of emergency responders. In the United States, federal, state, and local agencies respond with the necessary resources to address the consequences of nuclear and radiological incidents and monitor the affected population. Following the 2011 Fukushima Daiichi Nuclear Power Plant accident and the 2017 Gotham Shield National Level Exercise, the CDC recognized an opportunity to improve their practices by establishing a more efficient and timely health effect surveillance system before another incident occurs. On March 12-13th, 2019, the National Academies convened a workshop to discuss the process for preparing a radiation registry for monitoring long-term health effects of populations affected by a nuclear or radiological incident. Participants assessed existing information, useful practices, and tools for planning a radiation registry that will enhance incident monitoring and response methods. This publication summarizes the discussions and presentations from the workshop. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T Gulf War and Health: Volume 11: Generational Health Effects of Serving in the Gulf War %@ 978-0-309-47823-6 %D 2018 %U https://nap.nationalacademies.org/catalog/25162/gulf-war-and-health-volume-11-generational-health-effects-of %> https://nap.nationalacademies.org/catalog/25162/gulf-war-and-health-volume-11-generational-health-effects-of %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 518 %X For the United States, the 1991 Persian Gulf War was a brief and successful military operation with few injuries and deaths. However, soon after returning from duty, a large number of veterans began reporting health problems they believed were associated with their service in the Gulf. At the request of Congress, the National Academies of Sciences, Engineering, and Medicine has been conducting an ongoing review of the evidence to determine veterans' long-term health problems and potential causes. Some of the health effects identified by past reports include post-traumatic stress disorders, other mental health disorders, Gulf War illness, respiratory effects, and self-reported sexual dysfunction. Veterans' concerns regarding the impacts of deployment-related exposures on their health have grown to include potential adverse effects on the health of their children and grandchildren. These concerns now increasingly involve female veterans, as more women join the military and are deployed to war zones and areas that pose potential hazards. Gulf War and Health: Volume 11 evaluates the scientific and medical literature on reproductive and developmental effects and health outcomes associated with Gulf War and Post-9/11 exposures, and designates research areas requiring further scientific study on potential health effects in the descendants of veterans of any era. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Wizemann, Theresa M. %T Exploring Early Childhood Care and Education Levers to Improve Population Health: Proceedings of a Workshop %@ 978-0-309-47683-6 %D 2019 %U https://nap.nationalacademies.org/catalog/25129/exploring-early-childhood-care-and-education-levers-to-improve-population-health %> https://nap.nationalacademies.org/catalog/25129/exploring-early-childhood-care-and-education-levers-to-improve-population-health %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 124 %X On September 14, 2017, the Roundtable on Population Health Improvement of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the intersection of health and early childhood care and education, two key social determinants of health. This workshop follows a 2014 roundtable workshop that considered the interface between the education and health sectors broadly, from research and metrics to cross-sectoral partnerships and financing. The 2017 workshop continued that discussion, with a deeper focus on early childhood (birth through age 5) as a critical period in human development and an important opportunity for educational and related interventions. This publication summarizes the presentations and discussions from the 2017 workshop. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Olson, Steve %E Wojtowicz, Alexis %T Integrating Oral and General Health Through Health Literacy Practices: Proceedings of a Workshop %@ 978-0-309-49348-2 %D 2019 %U https://nap.nationalacademies.org/catalog/25468/integrating-oral-and-general-health-through-health-literacy-practices-proceedings %> https://nap.nationalacademies.org/catalog/25468/integrating-oral-and-general-health-through-health-literacy-practices-proceedings %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 122 %X Oral health care and medical health care both seek to maintain and enhance human health and well-being. Yet, dentistry and primary care in the United States are largely separated and isolated from each other. Each has its own siloed systems for education, service delivery, financing, and policy oversight. The result has been duplication of effort, a cultural gap between the two professions, and lost opportunities for productive collaboration and better health. On December 6, 2018, in Washington, DC, the National Academies of Sciences, Engineering, and Medicine held a workshop titled Integrating Oral and General Health Through Health Literacy Practices. This publication summarizes the presentations and discussions from the workshop. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Pandya, Rajul %E Dibner, Kenne Ann %T Learning Through Citizen Science: Enhancing Opportunities by Design %@ 978-0-309-47916-5 %D 2018 %U https://nap.nationalacademies.org/catalog/25183/learning-through-citizen-science-enhancing-opportunities-by-design %> https://nap.nationalacademies.org/catalog/25183/learning-through-citizen-science-enhancing-opportunities-by-design %I The National Academies Press %C Washington, DC %G English %K Education %P 204 %X In the last twenty years, citizen science has blossomed as a way to engage a broad range of individuals in doing science. Citizen science projects focus on, but are not limited to, nonscientists participating in the processes of scientific research, with the intended goal of advancing and using scientific knowledge. A rich range of projects extend this focus in myriad directions, and the boundaries of citizen science as a field are not clearly delineated. Citizen science involves a growing community of professional practitioners, participants, and stakeholders, and a thriving collection of projects. While citizen science is often recognized for its potential to engage the public in science, it is also uniquely positioned to support and extend participants' learning in science. Contemporary understandings of science learning continue to advance. Indeed, modern theories of learning recognize that science learning is complex and multifaceted. Learning is affected by factors that are individual, social, cultural, and institutional, and learning occurs in virtually any context and at every age. Current understandings of science learning also suggest that science learning extends well beyond content knowledge in a domain to include understanding of the nature and methods of science. Learning Through Citizen Science: Enhancing Opportunities by Design discusses the potential of citizen science to support science learning and identifies promising practices and programs that exemplify the promising practices. This report also lays out a research agenda that can fill gaps in the current understanding of how citizen science can support science learning and enhance science education. %0 Book %A Institute of Medicine %T Healthy, Resilient, and Sustainable Communities After Disasters: Strategies, Opportunities, and Planning for Recovery %@ 978-0-309-31619-4 %D 2015 %U https://nap.nationalacademies.org/catalog/18996/healthy-resilient-and-sustainable-communities-after-disasters-strategies-opportunities-and %> https://nap.nationalacademies.org/catalog/18996/healthy-resilient-and-sustainable-communities-after-disasters-strategies-opportunities-and %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %K Conflict and Security Issues %P 504 %X In the devastation that follows a major disaster, there is a need for multiple sectors to unite and devote new resources to support the rebuilding of infrastructure, the provision of health and social services, the restoration of care delivery systems, and other critical recovery needs. In some cases, billions of dollars from public, private and charitable sources are invested to help communities recover. National rhetoric often characterizes these efforts as a "return to normal." But for many American communities, pre-disaster conditions are far from optimal. Large segments of the U.S. population suffer from preventable health problems, experience inequitable access to services, and rely on overburdened health systems. A return to pre-event conditions in such cases may be short-sighted given the high costs - both economic and social - of poor health. Instead, it is important to understand that the disaster recovery process offers a series of unique and valuable opportunities to improve on the status quo. Capitalizing on these opportunities can advance the long-term health, resilience, and sustainability of communities - thereby better preparing them for future challenges. Healthy, Resilient, and Sustainable Communities After Disasters identifies and recommends recovery practices and novel programs most likely to impact overall community public health and contribute to resiliency for future incidents. This book makes the case that disaster recovery should be guided by a healthy community vision, where health considerations are integrated into all aspects of recovery planning before and after a disaster, and funding streams are leveraged in a coordinated manner and applied to health improvement priorities in order to meet human recovery needs and create healthy built and natural environments. The conceptual framework presented in Healthy, Resilient, and Sustainable Communities After Disasters lays the groundwork to achieve this goal and provides operational guidance for multiple sectors involved in community planning and disaster recovery. Healthy, Resilient, and Sustainable Communities After Disasters calls for actions at multiple levels to facilitate recovery strategies that optimize community health. With a shared healthy community vision, strategic planning that prioritizes health, and coordinated implementation, disaster recovery can result in a communities that are healthier, more livable places for current and future generations to grow and thrive - communities that are better prepared for future adversities. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T Why Indoor Chemistry Matters %@ 978-0-309-08399-7 %D 2022 %U https://nap.nationalacademies.org/catalog/26228/why-indoor-chemistry-matters %> https://nap.nationalacademies.org/catalog/26228/why-indoor-chemistry-matters %I The National Academies Press %C Washington, DC %G English %K Math, Chemistry, and Physics %K Environment and Environmental Studies %P 190 %X People spend the vast majority of their time inside their homes and other indoor environments where they are exposed to a wide range of chemicals from building materials, furnishings, occupants, cooking, consumer products, and other sources. Despite research to date, very little is known about how exposures to indoor chemicals across complex chemical phases and pathways affect human health. The COVID-19 pandemic has only increased public awareness of indoor environments and shed light on the many outstanding questions about how best to manage chemicals indoors. This report identifies gaps in current research and understanding of indoor chemistry and new approaches that can be applied to measure, manage, and limit chemical exposures. Why Indoor Chemistry Matters calls for further research about the chemical transformations that can occur indoors, pathways and timing of indoor chemical exposure, and the cumulative and long-term impacts of exposure on human health. Research priorities should consider factors that contribute to measurable environmental health disparities that affect vulnerable populations, such as the age, location, and condition of buildings that can alter exposures to indoor chemicals. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T Veterans and Agent Orange: Update 11 (2018) %@ 978-0-309-47716-1 %D 2018 %U https://nap.nationalacademies.org/catalog/25137/veterans-and-agent-orange-update-11-2018 %> https://nap.nationalacademies.org/catalog/25137/veterans-and-agent-orange-update-11-2018 %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 738 %X From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academies of Sciences, Engineering, and Medicine was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 11 (2018) examines peer-reviewed scientific reports concerning associations between various health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published between September 30, 2014, and December 31, 2017, and integrates this information with the previously established evidence database.