TY - BOOK AU - National Research Council AU - Institute of Medicine TI - Stem Cells and the Future of Regenerative Medicine SN - DO - 10.17226/10195 PY - 2002 UR - https://nap.nationalacademies.org/catalog/10195/stem-cells-and-the-future-of-regenerative-medicine PB - The National Academies Press CY - Washington, DC LA - English KW - Biology and Life Sciences KW - Health and Medicine AB - Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell research—specifically embryonic stem cell research—into the political crosshairs. President Bush’s watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues. ER - TY - BOOK AU - Institute of Medicine A2 - Emily Ann Meyer A2 - Kathi Hanna A2 - Kristine Gebbie TI - Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program SN - DO - 10.17226/11269 PY - 2005 UR - https://nap.nationalacademies.org/catalog/11269/cord-blood-establishing-a-national-hematopoietic-stem-cell-bank-program PB - The National Academies Press CY - Washington, DC LA - English KW - Health and Medicine AB - With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines: The role of cord blood in stem cell transplantation The current status of blood banks already in existence The optimal structure for the cord blood program The current use and utility of cord blood for stem cell transplants The best way to advance the use of cord blood units and make them available for research Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders. ER - TY - BOOK AU - National Research Council TI - Scientific and Medical Aspects of Human Reproductive Cloning SN - DO - 10.17226/10285 PY - 2002 UR - https://nap.nationalacademies.org/catalog/10285/scientific-and-medical-aspects-of-human-reproductive-cloning PB - The National Academies Press CY - Washington, DC LA - English KW - Biology and Life Sciences KW - Health and Medicine AB - Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would be—or would not be—acceptable to individuals or society. ER - TY - BOOK AU - Institute of Medicine AU - National Research Council TI - Guidelines for Human Embryonic Stem Cell Research SN - DO - 10.17226/11278 PY - 2005 UR - https://nap.nationalacademies.org/catalog/11278/guidelines-for-human-embryonic-stem-cell-research PB - The National Academies Press CY - Washington, DC LA - English KW - Health and Medicine AB - Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research. ER -