%0 Book %A National Research Council %T Managing for High-Quality Science and Engineering at the NNSA National Security Laboratories %@ 978-0-309-25437-3 %D 2013 %U https://nap.nationalacademies.org/catalog/13367/managing-for-high-quality-science-and-engineering-at-the-nnsa-national-security-laboratories %> https://nap.nationalacademies.org/catalog/13367/managing-for-high-quality-science-and-engineering-at-the-nnsa-national-security-laboratories %I The National Academies Press %C Washington, DC %G English %K Conflict and Security Issues %P 98 %X The three National Security Laboratories--Los Alamos National Laboratory (LANL), Sandia National Laboratories (SNL), and Lawrence Livermore National Laboratory (LLNL)--are managed by private-sector entities under contract to the National Nuclear Security Administration (NNSA). The FY2010 Defense Authorization Act mandated that NNSA task the National Research Council (NRC) to study the quality and management of Science and Engineering (S&E) at these Laboratories. This study (addressing a total of 5 tasks) is being conducted in two phases. This report covers the first phase, which addresses the relationship between the quality of the science and engineering at the Laboratory and the contract for managing and operating the Laboratory (task 4), and also addresses the management of work conducted by the Laboratory for entities other than the Department of Energy (task 5). The study's second phase will evaluate the actual quality of S&E in key subject areas. Managing for High-Quality Science and Engineering at the NNSA National Security Laboratories presents assessments of the evolution of the mission of the NNSA Labs and the management and performance of research in support of the missions, and the relationship between the Laboratory Directed Research and Development (LDRD) program and the ability of the Labs to fulfill their mission. The report examines the framework for managing science and engineering research at the Labs and provides an analysis of the relationships among the several players in the management of the Labs--the NNSA, the site offices, the contractors, and the Lab managers--and the effect of that relationship on the Laboratories' ability to carry out science and engineering research. %0 Book %A National Research Council %T Protecting the Frontline in Biodefense Research: The Special Immunizations Program %@ 978-0-309-20924-3 %D 2011 %U https://nap.nationalacademies.org/catalog/13112/protecting-the-frontline-in-biodefense-research-the-special-immunizations-program %> https://nap.nationalacademies.org/catalog/13112/protecting-the-frontline-in-biodefense-research-the-special-immunizations-program %I The National Academies Press %C Washington, DC %G English %K Conflict and Security Issues %P 184 %X The U.S. Army's Special Immunizations Program is an important component of an overall biosafety program for laboratory workers at risk of exposure to hazardous pathogens. The program provides immunizations to scientists, laboratory technicians and other support staff who work with certain hazardous pathogens and toxins. Although first established to serve military personnel, the program was expanded through a cost-sharing agreement in 2004 to include other government and civilian workers, reflecting the expansion in biodefense research in recent years. Protecting the Frontline in Biodefense Research examines issues related to the expansion of the Special Immunizations Program, considering the regulatory frameworks under which the vaccines are administered, how additional vaccines might be considered for inclusion in the Program, and factors that might influence the development and manufacturing of vaccines for the Special Immunizations Program. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Benjamin, Georges C. %E Brown, Lisa %E Carlin, Ellen %T Strengthening the Disaster Resilience of the Academic Biomedical Research Community: Protecting the Nation's Investment %@ 978-0-309-46249-5 %D 2017 %U https://nap.nationalacademies.org/catalog/24827/strengthening-the-disaster-resilience-of-the-academic-biomedical-research-community %> https://nap.nationalacademies.org/catalog/24827/strengthening-the-disaster-resilience-of-the-academic-biomedical-research-community %I The National Academies Press %C Washington, DC %G English %K Conflict and Security Issues %P 450 %X The academic biomedical research community is a hub of employment, economic productivity, and scientific progress. Academic research institutions are drivers of economic development in their local and state economies and, by extension, the national economy. Beyond the economic input that the academic biomedical research community both receives and provides, it generates knowledge that in turn affects society in myriad ways. The United States has experienced and continues to face the threat of disasters, and, like all entities, the academic biomedical research community can be affected. Recent disasters, from hurricanes to cyber-attacks, and their consequences have shown that the investments of the federal government and of the many other entities that sponsor academic research are not uniformly secure. First and foremost, events that damage biomedical laboratories and the institutions that house them can have impacts on the safety and well-being of humans and research animals. Furthermore, disasters can affect career trajectories, scientific progress, and financial stability at the individual and institutional levels. Strengthening the Disaster Resilience of the Academic Biomedical Research Community offers recommendations and guidance to enhance the disaster resilience of the academic biomedical research community, with a special focus on the potential actions researchers, academic research institutions, and research sponsors can take to mitigate the impact of future disasters. %0 Book %A National Academy of Sciences %E Guenther, Rita S. %E Lowenthal, Micah D. %T Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety: Summary of a Workshop %@ 978-0-309-37866-6 %D 2016 %U https://nap.nationalacademies.org/catalog/21810/indo-us-workshop-on-challenges-of-emerging-infections-and-global-health-safety %> https://nap.nationalacademies.org/catalog/21810/indo-us-workshop-on-challenges-of-emerging-infections-and-global-health-safety %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 214 %X The United States and India have pledged to deepen the linkages between their people, their businesses, and their governments for the mutual benefit of both countries and for the promotion of global peace, stability, economic growth and prosperity. Both nations are now inclined to improve relations and cooperation, but the nations need specific actions that will yield progress and build confidence and momentum for further cooperation. The Indo-U.S. Workshop on Challenges of Emerging Infections and Global Health Safety, held in November 2014, encouraged scientists from both countries to examine global issues related to emerging and existing infections and global health safety, to share experience and approaches, and to identify opportunities for cooperation to improve practice and research in these areas. This report summarizes the presentations and discussions from the workshop. %0 Book %A National Research Council %T Guide for the Care and Use of Laboratory Animals: Eighth Edition %@ 978-0-309-15400-0 %D 2011 %U https://nap.nationalacademies.org/catalog/12910/guide-for-the-care-and-use-of-laboratory-animals-eighth %> https://nap.nationalacademies.org/catalog/12910/guide-for-the-care-and-use-of-laboratory-animals-eighth %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Agriculture %P 246 %X A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.