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Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals (2001)

Chapter: J List of Extant Standards and Guidelines in a Technical Support Document

« Previous: I Example of the AEGL Derivation Summary Appendix in a Technical Support Document
Suggested Citation:"J List of Extant Standards and Guidelines in a Technical Support Document." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
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Appendix J
List of Extant Standards and Guidelines in A Technical Support Document

Section 8.2 of the technical support document (TSD) compares the AEGL values for a chemical with other standards and guidelines previously published for exposure durations ranging from 10 min to 8 h. A summary discussion of important comparisons should be presented in the text and the values for recognized standards and guidelines, if available, should be presented in the table. The statement, “All currently available standards and guidelines are shown in Table…” should be included in the text to affirm completeness of the table. Only those standards or guidelines with published values for a given chemical should be included in the table. In cases where the exposure duration of a published standard or guideline differs from those designated for AEGLs (e.g., 15-min PEL-STEL), the value should be placed in parentheses in the column of the closest AEGL exposure duration category and footnoted to indicate its true exposure duration. A list of recognized standards and guidelines and the order in which they should appear in the following table.

Suggested Citation:"J List of Extant Standards and Guidelines in a Technical Support Document." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
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LIST AND ORDER OF PRESENTATION OF EXTANT STANDARDS AND GUIDELINES IN THE TSD TABLE

AEGL-1

acute exposure guideline level-1

AEGL-2

acute exposure guideline level-2

AEGL-3

acute exposure guideline level-3

ERPG-1 (AIHA)

emergency response planning guideline-level 1

ERPG-2 (AIHA)

emergency response planning guideline-level 2

ERPG-3 (AIHA)

emergency response planning guideline-level 3

SPEGL (NRC)

short-term emergency guidance level

EEL (NRC)

emergency exposure limit

STPL (NRC)

short-term public limit

CEL (NRC)

continuous exposure limit

EEGL (NRC)

emergency exposure guidance level

SMAC (NRC)

spacecraft maximum allowable concentration for space-station contaminants

PEL-STEL (OSHA)

permissible exposure limit-short-term exposure limit

PEL-TWA (OSHA)

permissible exposure limit-time weighted average

IDLH (NIOSH)

immediately dangerous to life and health

REL-STEL (NIOSH)

recommended exposure limit

TLV-STEL (ACGIH)

Threshold Limit Value-short-term exposure limit

TLV-TWA (ACGIH)

Threshold Limit Value-time-weighted average

MAC (Netherlands)

maximum acceptable concentration

MAK (Germany)

[maximale arbeitsplatzkonzentration] maximum workplace concentration, 8-h time weighted average, German Research Association

MAK S. (Germany)

spitzenbegrenzung (kategorie ii, 2) [peak limit II, 2] 30 min×2 per day

einsatztoleranzwert (Germany)

action tolerance levels

Suggested Citation:"J List of Extant Standards and Guidelines in a Technical Support Document." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 201
Suggested Citation:"J List of Extant Standards and Guidelines in a Technical Support Document." National Research Council. 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: The National Academies Press. doi: 10.17226/10122.
×
Page 202
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Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures.

The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment.

It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routes—both oral and dermal—as well as risk assessors in the government, academe, and private industry.

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