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Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
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Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
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Page 58
Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
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Page 59
Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
×
Page 60
Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
×
Page 61
Suggested Citation:"Appendix: Committee and Staff Biographies." Institute of Medicine. 2004. Veterans and Agent Orange: Length of Presumptive Period for Association Between Exposure and Respiratory Cancer. Washington, DC: The National Academies Press. doi: 10.17226/10933.
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Page 62

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Appendix Committee and Staff Biographies Irva Hertz-Picciotto, PhD (Chair), is professor in the Department of Epidemi- ology and Preventive Medicine and deputy director of the Children's Center for Environmental Health at the University of California, Davis. She has published extensively on methods of epidemiologic data analysis, occupation-related can- cer, environmental exposures, reproductive and developmental outcomes, and risk assessment. Dr. Hertz-Picciotto serves on editorial boards for Epidemiology, American Journal of Epidemiology, and Environmental Health Perspectives, as well as the Board of Scientific Counselors for the National Institute of Environ- mental Health Sciences, the Scientific Advisory Board for the US Environmen- tal Protection Agency, and California Governor's Carcinogen Identification Com- mittee. She is past president of the International Society for Environmental Epidemiology and was recently an invited delegate to the US­Vietnam Scien- tific Conference on the Environmental and Health Effects of the Vietnam War. Dr. Hertz-Picciotto also served as chair of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Bien- nial Updates). Kiros T. Berhane, PhD, is an assistant professor in the Department of Preven- tive Medicine at the University of Southern California. He has conducted research on longitudinal time-series analysis, flexible-modeling techniques, modeling time-to-event data, and latency. Dr. Berhane received his PhD in biostatistics from the University of Toronto (Canada) and completed a postdoctoral fellowship in biostatistics at Johns Hopkins University (1994­ 1995). He is a member of a scientific advisory panel for an air-pollution study under the auspices of the Western Interprovincial Scientific Studies Association 57

58 VETERANS AND AGENT ORANGE (WISSA) in Canada. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Bi- ennial Update). Margit L. Bleecker, MD, PhD, is director of the Center for Occupational and Environmental Neurology in Baltimore. Her research interests are in clinical industrial neurotoxicology and occupational neurology. Dr. Bleecker recently served on the Institute of Medicine (IOM) Committee on the Safety of Silicone Breast Implants and has served on the IOM Committee on the Evaluation of the Department of Defense Comprehensive Clinical Evaluation Protocol and the IOM Committee on the Persian Gulf Syndrome Comprehensive Clinical Evalua- tion Program. She also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Biennial Updates). Paul F. Engstrom, MD, is senior vice president of population science, oversee- ing Fox Chase programs in behavioral research, human genetics, epidemiologic research, and cancer-prevention research. He is also medical director of the Fox Chase Network and the International Programs for Fox Chase Cancer Center. Dr. Engstrom is a medical oncologist specializing in gastrointestinal cancers. He is a member of the National Cancer Institute (NCI) Cancer Epidemiology, Pre- vention and Control Review Committee and the American Cancer Society Coun- cil for Extramural Grants. He is former chair of the Board of Scientific Counse- lors for NCI's Division of Cancer Prevention and Control and former chair of NCI's Committee on Treatment Strategies to Cut Cancer-Death Rates in Half By the Year 2000. Dr. Engstrom is a member of the editorial board of Cancer Epidemiology Biomarkers & Prevention, The Journal of Cancer Prevention and The Journal of Clinical Oncology, and he is the author or coauthor of several texts and book chapters on cancer control and medical oncology. He also served as a member of the Committee to Review the Health Effects in Vietnam Veter- ans of Exposure to Herbicides (Fourth Biennial Update). Richard A. Fenske, PhD, is professor of environmental health in the Industrial Hygiene and Safety Program at the University of Washington School of Public Health and Community Medicine and is the director of the Pacific Northwest Agricultural Safety and Health Center. Dr. Fenske's work has focused on the evaluation of environmental health risks in special populations. His specialties include health risks posed by pesticide exposures, development of new exposure-assessment methods, and investigation of the role of skin exposure of workers and children. Dr. Fenske serves on the editorial review boards of Ap- plied Occupational and Environmental Hygiene and the Journal of Agricultural Safety and Health. He also served as a member of the Committee to Review the

APPENDIX 59 Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update). Thomas A. Gasiewicz, PhD, is professor and chairman of the Department of Environmental Medicine and director of the Environmental Health Sciences Cen- ter at the University of Rochester School of Medicine. He serves on the editorial board of Biochemical Pharmacology, and Toxicology and Applied Pharmacol- ogy, as well as the National Toxicology Program Board of Counselors. He also is a peer reviewer for several other scientific journals, including Cancer Research, Molecular Pharmacology, Carcinogenesis, Science, Toxicological Sciences, and Archives of Biochemistry and Biophysics. Dr. Gasiewicz has published exten- sively on the toxicokinetics of dioxin, dioxin toxicity, and the role of the aryl hydrocarbon receptor in the molecular mechanism of dioxin toxicity. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Biennial Updates). Tee L. Guidotti, MD, MPH, is the chair of the Department of Environmental and Occupational Health in the School of Public Health and Health Services of the George Washington University. He is also director of the Division of Occu- pational Medicine and Toxicology in the Department of Medicine of George Washington University School of Medicine and Health Science and is cross- appointed as professor of pulmonary medicine, health policy, and epidemiology. Dr. Guidotti is certified as a specialist in internal medicine, lung diseases, and occupational medicine. His primary research interests are air quality, inhalation toxicology, and occupational and environmental lung diseases. Dr. Guidotti is past president of the Association of Occupational and Environmental Clinics and sits on the Board of Directors of the American College of Occupational and Environmental Medicine and of the International Commission on Occupational Health. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Bien- nial Updates). Loren D. Koller, DVM, PhD, served in academe for nearly 30 years, the last 16 as professor in the College of Veterinary Medicine of Oregon State University, Corvallis. For 10 of those years, he served as dean of the college. He operates a business in environmental health and toxicology. Dr. Koller pioneered the disci- pline now known as immunotoxicology with a research focus also in toxicology, pathology, carcinogenesis, and risk assessment. He is on the Institute of Medi- cine Committee on the Assessment of Wartime Exposure to Herbicides in Viet- nam and served for 6 years as a member of the National Research Council Committee on Toxicology. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Biennial Updates).

60 VETERANS AND AGENT ORANGE John J. Stegeman, PhD, is senior scientist and chair of the Biology Depart- ment at the Woods Hole Oceanographic Institution. He received his PhD in biochemistry, concentrating on enzymology, from Northwestern University. His research centers on metabolism of foreign chemicals in animals and humans and on the structure, function, and regulation of the enzymes that accomplish this metabolism. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Biennial Updates). David S. Strogatz, PhD, MSPH, is associate professor and chair of the Depart- ment of Epidemiology of the University at Albany, State University of New York. He is also director of the Prevention Research Center of the School of Public Health of the University at Albany. Dr. Strogatz received his MSPH and PhD in epidemiology from the University of North Carolina, Chapel Hill. His research examines the epidemiology of cardiovascular disease and diabetes and the impact of socioeconomic status and race on health. He also served as a member of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Third and Fourth Biennial Updates). STAFF Rose Marie Martinez, ScD, is director of the Institute of Medicine (IOM) Board on Health Promotion and Disease Prevention. Before joining IOM, she was a senior health researcher at Mathematica Policy Research, where she conducted research on the impact of health-system change on the public-health infrastruc- ture, access to care for vulnerable populations, managed care, and the health- care workforce. Dr. Martinez is a former assistant director for health financing and policy with the US General Accounting Office, where she directed evalua- tions and policy analysis in national and public-health issues. Dr. Martinez re- ceived her doctorate from the Johns Hopkins School of Hygiene and Public Health. Michelle Catlin, PhD, is a program officer in the Institute of Medicine (IOM) Board on Health Promotion and Disease Prevention. Before joining IOM, she served as a program officer with the Board on Environmental Studies and Toxi- cology of the National Research Council. She received her MSc in pharmacol- ogy and toxicology from Queen's University, Canada, and a PhD in environ- mental health (Toxicology Program) from the University of Washington. Dr. Catlin has worked on numerous National Academies reports, including Copper in Drinking Water, Toxicological Effects of Methylmercury, Arsenic in Drinking Water: 2001 Update, and Veterans and Agent Orange: Update 2002.

APPENDIX 61 Jennifer A. Cohen is a research associate in the Institute of Medicine (IOM) Board on Health Promotion and Disease Prevention. She received her under- graduate degree in art history from the University of Maryland. She has also been involved with the IOM committees that produced Organ Procurement and Transplantation; Clearing the Air: Asthma and Indoor Air Exposures; Veterans and Agent Orange: Herbicide/Dioxin Exposure and Type 2 Diabetes; Veterans and Agent Orange: Update 2000; and Veterans and Agent Orange: Herbicide/ Dioxin Exposure and Acute Myelogenous Leukemia in the Children of Vietnam Veterans. Elizabeth J. Albrigo is a project assistant in the Institute of Medicine (IOM) Board on Health Promotion and Disease Prevention. She received her under- graduate degree in psychology from the Virginia Polytechnic Institute and State University. She has been involved with the IOM Committee on the Review of the USDA E. coli O157: H7 Farm-to-Table Process Risk Assessment and the Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam. Joe A. Esparza is a senior project assistant in the Institute of Medicine (IOM) Board on Health Promotion and Disease Prevention. He attended Columbia University, where he studied biochemistry. Before joining IOM, he worked with the Board on Agriculture and Natural Resources of the National Research Council, where he was involved with the committees that produced Frontiers in Agricultural Research: Food, Health, Environment, and Communities; Air Emis- sions from Animal Feeding Operations: Current Knowledge, Future Needs; and Publicly Funded Agricultural Research and the Changing Structure of US Agriculture.

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From 1962 to 1971, US military forces sprayed herbicides over Vietnam to strip the thick jungle canopy that helped conceal opposition forces, to destroy crops that enemy forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the majority of the herbicides sprayed. Agent Orange was a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, one form of dioxin) was an unintended contaminant from the production of 2,4,5-T and was present in Agent Orange and some other formulations sprayed in Vietnam.

In 1991, because of continuing uncertainty about the long-term health effects on Vietnam veterans of the herbicides sprayed, Congress passed Public Law 102-4, the Agent Orange Act of 1991. In response to the request from the VA, IOM extended the service of the Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides that was responsible for Update 2002 to address the question of presumptive period and respiratory cancer. The charge to the committee was to undertake a review and evaluation of the evidence regarding the period between cessation of exposure to herbicides used in Vietnam and their contaminants (2,4-D, 2,4,5-T and its contaminant TCDD, cacodylic acid, and picloram) and the occurrence of respiratory cancer.

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