National Academies Press: OpenBook
Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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THE PROTEUS EFFECT

Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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Other titles by Ann B. Parson

Menopause, coauthored with Isaac Schiff

Decoding Darkness: The Search for the Genetic Causes of Alzheimer’s Disease, coauthored with Rudolph E. Tanzi

Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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THE PROTEUS EFFECT

STEM CELLS AND THEIR PROMISE FOR MEDICINE

Ann B. Parson

Joseph Henry Press
Washington, D.C.

Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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Joseph Henry Press
500 Fifth Street, NW Washington, DC 20001

The Joseph Henry Press, an imprint of the National Academies Press, was created with the goal of making books on science, technology, and health more widely available to professionals and the public. Joseph Henry was one of the founders of the National Academy of Sciences and a leader in early American science.

Any opinions, findings, conclusions, or recommendations expressed in this volume are those of the author and do not necessarily reflect the views of the National Academy of Sciences or its affiliated institutions.

Library of Congress Cataloging-in-Publication Data

Parson, Ann B.

The Proteus effect : stem cells and their promise for medicine / by Ann B. Parson.

p. ; cm.

Includes bibliographical references and index.

ISBN 0-309-08988-3 (cloth with jacket) ISBN 0-309-53329-5 (PDF)

1. Stem cells—Research—History. 2. Stem cells—Popular works. [DNLM: 1. Research—history. 2. Stem Cells. 3. Stem Cell

Transplantation. QH 581.2 P266p 2004] I. Title.

QH588.S83P37 2004

616'.02774—dc22

2004013757

Cover image: © Victor Habbick Visions/Photo Researchers, Inc.

Copyright 2004 by Ann B. Parson. All rights reserved.

Printed in the United States of America.

Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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For my mother, who showed me color

For Streaker, who basks in the natural

Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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Suggested Citation:"Front Matter." Ann B. Parson. 2004. The Proteus Effect: Stem Cells and Their Promise for Medicine. Washington, DC: Joseph Henry Press. doi: 10.17226/11003.
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Proteus—a Sea God and Ocean Shepard for Poseidon’s seals—was able to change shape when the occasion warranted.

Some have the gift to change and change again in many forms, like Proteus, creature of the encircling seas, who sometimes seemed a lad, sometimes a lion, sometimes a snake men feared to touch, sometimes a charging boar, or else a sharp-horned bull; often he was a stone, often a tree, or feigning flowing water seemed a river or water’s opposite a flame of fire.

—Metamorphoses 8.731

To Proteus. Proteus I call, whom fate decrees to keep the keys which lock the chambers of the deep; first-born, by whose illustrious power alone all nature’s principles were clearly shown. Pure sacred matter to transmute is thine, and decorate with forms all-various and divine. All-honoured, prudent, whose sagacious mind knows all that was and is of every kind, with all that shall be in succeeding time, so vast thy wisdom, wondrous and sublime: for all things Nature first to thee consigned, and in thy essence omniform confined. O father, to the mystics’ rites attend, and grant, a blessed life a prosperous end.

—Orphic Hymn 25 to Proteus

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Next: Introduction »
The Proteus Effect: Stem Cells and Their Promise for Medicine Get This Book
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 The Proteus Effect: Stem Cells and Their Promise for Medicine

Stem cells could be the key that unlocks cures to scores of diseases and illnesses. Their story is at once compelling, controversial, and remarkable. Part detective story, part medical history, The Proteus Effect recounts the events leading up to the discovery of stem cells and their incredible potential for the future of medicine.

What exactly are these biological wonders – these things called stem cells? They may be tiny, but their impact is earth shaking, generating excitement among medical researchers – and outright turmoil in political circles. They are reported to be nothing short of miraculous. But they have also incited fear and mistrust in many. Indeed, recent research on stem cells raises important questions as rapidly as it generates new discoveries.

The power of stem cells rests in their unspecialized but marvelously flexible nature. They are the clay of life waiting for the cellular signal that will coax them into taking on the shape of the beating cells of the heart muscle or the insulin-producing cells of the pancreas. With a wave of our medical magic wand, it's possible that stem cells could be used to effectively treat (even cure) diseases such as Parkinson's disease, diabetes, heart disease, autoimmune disorders, and even baldness.

But should scientists be allowed to pick apart four-day-old embryos in order to retrieve stem cells? And when stem cells whisper to us of immortality – they can divide and perpetuate new cells indefinitely – how do we respond? Stem cells are forcing us to not only reexamine how we define the beginning of life but how we come to terms with the end of life as well.

Meticulously researched, artfully balanced, and engagingly told, Ann Parson chronicles a scientific discovery in progress, exploring the ethical debates, describing the current research, and hinting of a spectacular new era in medicine. The Proteus Effect is as timely as it is riveting.

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