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Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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Capturing the Full Power of Biomaterials for Military Medicine

Report of a Workshop

Committee on Capturing the Full Power of Biomaterials for Military Medical Needs

Board on Manufacturing and Engineering Design

National Materials Advisory Board

Division on Engineering and Physical Sciences

NATIONAL RESEARCH COUNCIL OF THE NATIONAL ACADEMIES

THE NATIONAL ACADEMIES PRESS
Washington, D.C. www.nap.edu

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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THE NATIONAL ACADEMIES PRESS
500 Fifth Street, N.W. Washington, DC 20001

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

This study was supported by Contract DOD-4996 between the National Academy of Sciences and the Department of Defense. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of the organizations or agencies that provided support for the project.

International Standard Book Number 0-309-09283-3 (POD)

Available in limited supply from:

National Materials Advisory Board

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Additional copies of this report are available from the
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Copyright 2004 by the National Academy of Sciences. All rights reserved.

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Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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THE NATIONAL ACADEMIES

Advisers to the Nation on Science, Engineering, and Medicine

The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Bruce M. Alberts is president of the National Academy of Sciences.

The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. Wm. A. Wulf is president of the National Academy of Engineering.

The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Harvey V. Fineberg is president of the Institute of Medicine.

The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy's purposes of furthering knowledge and advising the federal government. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Bruce M. Alberts and Dr. Wm. A. Wulf are chair and vice chair, respectively, of the National Research Council.

www.national-academies.org

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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COMMITTEE ON CAPTURING THE FULL POWER OF BIOMATERIALS FOR MILITARY MEDICAL NEEDS

JAMES M. ANDERSON,

Case Western Reserve University, Cleveland, Ohio,

Chair

GARY W. CLEARY,

Corium International, Inc., Redwood City, California

ERIK A. HENCHAL,

U.S. Army Medical Research Institute of Infectious Disease, Ft. Detrick, Maryland

JOHN B. HOLCOMB,

U.S. Army Institute for Surgical Research, Ft. Sam Houston, Texas

JEFFREY O. HOLLINGER,

Carnegie Mellon University, Pittsburgh, Pennsylvania

ALAN LETTON,

Polymerix Corp., Piscataway, New Jersey

ARUNA NATHAN,

Ethicon, Inc., Somerville, New Jersey

JAQUES REIFMAN,

U.S. Army Medical Research and Materiel Command, Ft. Detrick, Maryland

JAMES SCHEIRER,

Robert Wood Johnson Medical School, New Brunswick, New Jersey

PETER P. TOLIAS,

Ortho-Clinical Diagnostics, a Johnson and Johnson company, Raritan, New Jersey

ROBERT H. VANDRE,

U.S. Army Medical Research and Materiel Command, Ft. Detrick, Maryland

Staff

TONI MARECHAUX, Study Director

MARTA VORNBROCK, Research Assistant

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
×

BOARD ON MANUFACTURING AND ENGINEERING DESIGN

PAMELA A. DREW,

The Boeing Company, Seattle, Washington,

Chair

CAROL L.J. ADKINS,

Sandia National Laboratories, Albuquerque, New Mexico

GREGORY AUNER,

Wayne State University, Detroit, Michigan

THOMAS W. EAGAR,

Massachusetts Institute of Technology, Cambridge

ROBERT E. FONTANA, JR.,

Hitachi Global Storage Technologies, San Jose, California

PAUL B. GERMERAAD,

Intellectual Assets, Inc., Saratoga, California

ROBERT M. HATHAWAY,

Oshkosh Truck Corporation, Oshkosh, Wisconsin

RICHARD L. KEGG,

Milacron, Inc. (retired), Cincinnati, Ohio

PRADEEP K. KHOSLA,

Carnegie Mellon University, Pittsburgh, Pennsylvania

JAY LEE,

University of Wisconsin, Milwaukee

DIANA L. LONG,

Robert C. Byrd Institute for Flexible Manufacturing, South Charleston, West Virginia

JAMES MATTICE,

Universal Technology Corporation, Dayton, Ohio

MANISH MEHTA,

National Center for Manufacturing Sciences, Ann Arbor, Michigan

ANGELO M. NINIVAGGI, JR.,

Plexus, Nampa, Idaho

JAMES B. O'DWYER,

PPG Industries, Allison Park, Pennsylvania

HERSCHEL H. REESE,

Dow Corning Corporation, Midland, Michigan

H.M. REININGA,

Rockwell Collins, Cedar Rapids, Iowa

LAWRENCE RHOADES,

Extrude Hone Corporation, Irwin, Pennsylvania

JAMES B. RICE, JR.,

Massachusetts Institute of Technology, Cambridge

ALFONSO VELOSA III,

Gartner, Inc., Tucson, Arizona

JACK WHITE,

Altarum, Ann Arbor, Michigan

JOEL SAMUEL YUDKEN,

AFL-CIO, Washington, D.C.

Staff

TONI MARECHAUX, Director

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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NATIONAL MATERIALS ADVISORY BOARD

JULIA M. PHILLIPS,

Sandia National Laboratories, Albuquerque, New Mexico,

Chair

JOHN ALLISON,

Ford Research Laboratories, Dearborn, Michigan

PAUL BECHER,

Oak Ridge National Laboratory, Tennessee

BARBARA D. BOYAN,

Georgia Institute of Technology, Atlanta

DIANNE CHONG,

The Boeing Company, St. Louis, Missouri

FIONA DOYLE,

University of California, Berkeley

GARY FISCHMAN,

Biomedical Applications of Materials Consultant, Palatine, Illinois

KATHARINE G. FRASE,

IBM, Hopewell Junction, New York

HAMISH L. FRASER,

Ohio State University, Columbus

JOHN J. GASSNER,

U.S. Army Natick Soldier Center, Massachusetts

THOMAS S. HARTWICK,

TRW (retired), Snohomish, Washington

ARTHUR H. HEUER,

Case Western Reserve University, Cleveland, Ohio

ELIZABETH HOLM,

Sandia National Laboratories, Albuquerque, New Mexico

FRANK E. KARASZ,

University of Massachusetts, Amherst

SHEILA F. KIA,

General Motors Research and Development Center, Warren, Michigan

CONILEE G. KIRKPATRICK,

HRL Laboratories, Malibu, California

ENRIQUE J. LAVERNIA,

University of California, Davis

TERRY LOWE,

Los Alamos National Laboratory, New Mexico

HENRY J. RACK,

Clemson University, Clemson, South Carolina

LINDA SCHADLER,

Rensselaer Polytechnic Institute, Troy, New York

JAMES C. SEFERIS,

University of Washington, Seattle

T.S. SUDARSHAN,

Materials Modification, Inc., Fairfax, Virginia

JULIA WEERTMAN,

Northwestern University, Evanston, Illinois

Staff

TONI MARECHAUX, Director

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
×

Preface

This document is the result of a technology planning process undertaken by the new Center for Military Biomaterials Research and the National Academies to begin closing the gap between available biomaterials-related technologies and the military’s needs. The critical first step in this process was the organization of a workshop, held in Iselin, New Jersey, on February 2-4, 2004. To ensure that the directions taken would be aligned with the military’s needs, participants included 15 senior U.S. Army officers and scientists who are experts in the health care needs of warfighters. Participants also included 27 industrial scientists and business leaders who provided the state of the art in commercial biomaterial product developments. The third constituency was the 40 academicians who presented the most recent basic and applied research concepts in the field.

The principal goal of the workshop was to explore a comprehensive approach to bringing new biomaterials technologies into service to fulfill the military's medical needs as early as possible. The workshop was intended to involve scientific, clinical, and business leaders from the field of medical biomaterials as knowledge sources and guides interacting with military scientists, clinicians, and program planners. The content was intended to address both the science contributing to biomaterials-based products and the corporate culture of technology companies working in biomaterials areas.

The technology development roadmap that is detailed here is the first step for enabling the military to modify and enhance its existing research and development programs in order to take best advantage of academic-based and corporate advances in biomaterials technology. A near-term benefit of implementing this roadmap will be advances in combat casualty care through focused attention on targeted modification of emerging industrial products to increase their suitability for use on the battlefield. Through the implementation of the technology development plan articulated in this roadmap, the Army’s interests will be connected with a comprehensive network of scientific leaders, core competency laboratories, and innovative companies.

This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the National Research Council's (NRC's) Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process.

The authors wish to thank the following individuals for their participation in the review of this report:

Pat Black, Picatinny Arsenal, U.S. Army

Gary Fischman, consultant to the biomaterials industry

Michael Helmus, Boston Scientific Corporation

Joshua Jacobs, Rush Medical College

Julie Swain, consultant to the Food and Drug Administration

Ranji Vaidyanathan, Advanced Ceramics Research, Inc.

Page viii Cite
Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the views expressed, nor did they see the final draft of the report before its release. The review of this report was overseen by Robert Frosch of Harvard University. Appointed by the NRC, Dr. Frosch was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.

The committee also acknowledges the invaluable contributions of Pablo Whaley, Michele Iacoletti, and Shara Williams, interns at the National Academies, in the preparation of this report. Barbara M. Boyan also greatly assisted the work of the committee through her participation in many of the committee's activities as liaison to the National Materials Advisory Board.

James M. Anderson, Chair

Committee on Capturing the Full Power of Biomaterials for Military Medical Needs

Suggested Citation:"Front Matter." National Research Council. 2004. Capturing the Full Power of Biomaterials for Military Medicine: Report of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/11063.
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Recent results in biomaterials R&D suggest that there are exceptional opportunities for these emerging materials in military medicine. To facilitate this possibility, the National Research Council convened a workshop at the request of the Department of Defense to help create a technology development roadmap to enhance military R&D into biomaterials technology. The workshop focused primarily on identifying useful near- and mid-term applications of biomaterials including wound care, tissue engineering, drug delivery, and physiological sensors and diagnostics. This report presents a summary of the workshop. It provides a review of biomaterials and their importance to military medicine, the roadmap, and a discussion of ways to enable biomaterials development. Several important outcomes of successful capture of potential benefits of these materials are also discussed.

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