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The Threat of Pandemic Influenza: Are We Ready? Workshop Summary (2005)

Chapter:Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response

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Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
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Appendix A
Pandemic Influenza: Assessing Capabilities for Prevention and Response

June 16–June 17, 2004

The National Academies

Lecture Room

2101 Constitution Avenue, NW (C Street Entrance)

Washington, D.C.

AGENDA

Wednesday, June 16, 2004

8:00

Continental Breakfast

8:30

Welcome and Opening Remarks

Adel Mahmoud, MD, PhD

Chair, Forum on Microbial Threats

President, Merck Vaccines

8:35

Keynote Address: John M. Barry, Distinguished Visiting Scholar, The Center for Bioenvironmental Research at Tulane and Xavier Universities, and author of The Great Influenza: The Epic Story of the Deadliest Plague in History

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

PLANNING AND PREPAREDNESS FOR PANDEMIC INFLUENZA

Session I: Global and National Preparedness Strategies

Moderator: Adel Mahmoud, MD, PhD, Chair, Forum on Microbial Threats/President, Merck Vaccines

9:05–9:35

WHO: Priority Public Health Interventions Before and During an Influenza Pandemic

Klaus Stöhr, DVM, Project Leader, Global Influenza Programme, Department of Communicable Disease Surveillance and Response, World Health Organization, Geneva

9:35–10:05

U.S. Government Pandemic Influenza Preparedness Plan Bruce Gellin, MD, Director, National Vaccine Program Office, U.S. Department of Health and Human Services

10:05

Q&A/Open Discussion

10:30

Break

Session II: Response and Discussion of Preparedness Planning

Moderator: Stanley Lemon, MD, Vice Chair, Forum on Microbial Threats and Dean of Medicine, The University of Texas Medical Branch at Galveston

10:45

Discussion Panel: David Fedson, MD, Sergy Haut, France

Nancy J. Cox, PhD, Chief, Influenza Branch, CDC and Director, WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza

Dennis Perrotta, PhD, State Epidemiologist, Texas

Peter A. Shult, PhD, Director, Communicable Disease Division and Emergency Laboratory Response, Wisconsin State Laboratory of Hygiene

11:15

Open Discussion

12:00

Lunch

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

Session III: Obstacles and Opportunities for Optimal Preparedness

Moderator: Gary Roselle, MD, Program Director for Infectious Diseases, Department of Veterans Affairs Central Office

1:00–1:20

Partnering with the Private Medical System

Gordon Grundy, MD, Regional Medical Director, Aetna Inc.

1:20–1:35

Discussion

1:35–1:55

Vaccine Development and Production Issues

Philip Hosbach, Vice President of New Products and Immunization Policy, Aventis Pasteur SA

1:55–2:10

Discussion

2:10–2:30

Ensuring an Adequate Stockpile of Antivirals

Paul Brown, PhD, Global Task Force Leader for Tamiflu™ Pandemic Planning, F. Hoffmann La-Roche, Switzerland

2:30–2:45

Discussion

2:45–3:05

Chasing the Elusive Virus: Preparing for the Future by Examining the Past

Jeffery K. Taubenberger, MD, PhD, Chair, Department of Molecular Pathology, Armed Forces Institute of Pathology, U.S. Department of Defense

3:05–3:20

Discussion

3:20

Break

Session IV: Panel Discussion—Innovating Past Barriers

Moderator: Joshua Lederberg, PhD, Nobel Laureate, Sackler Foundation Scholar, Rockefeller University

3:30–3:45

Strategies for Control of Influenza by Targeting Broadly Conserved Viral Features

Suzanne Epstein, PhD, Center for Biologics Evaluation and Research, Food and Drug Administration

3:45–4:10

Mathematical Modeling: Containing Pandemic Influenza with Vaccines and Antivirals

Ira Longini, MD, Rollins School of Public Health, Emory University, Atlanta, GA

March Lipsitch, PhD, Harvard School of Public Health, Boston, MA

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

4:10–4:25

Insuring” for a Better Response

Martin Meltzer, PhD, National Center for Infectious Diseases, U.S. Centers for Disease Control and Prevention

4:25–4:40

Coordination Between the Public and Private Sectors

Jonathan B. Perlin, MD, PhD, MSHA, FACP, Acting Under Secretary for Health, Department of Veterans Affairs

4:40–5:30

Q&A/Open Discussion

5:30

Adjournment of the First Day

Thursday, June 17, 2004

BATTLING NATURE’S TERRORIST: SCIENTIFIC AND PUBLIC HEALTH TOOLS

8:00

Continental Breakfast

8:30

Opening Remarks/Summary of Day 1

Stanley Lemon, MD

Vice Chair, Forum on Emerging Infections

Session V: Methods for the Prevention and Containment of Pandemic Influenza

Moderator: Carole Heilman, PhD, Director, Division of Microbiology and Infectious Diseases, NIAID, NIH

8:45–9:15

A Report from the Field: The 2003–2004 H5N1 Outbreak

Robert Webster, PhD, Rose Marie Thomas Professor and Chair, Department of Infectious Diseases, St. Jude’s Children’s Research Hospital, Memphis, TN

9:15–10:15

Discussion Panel: Amin Soebandrio, MD, PhD, Assistant Deputy Minister for Research and Technology for Health and Medical Sciences, Indonesia

Nguyen Tien Dzung, DVM, PhD, Head of Virology, National Institute for Veterinary Research, Ministry of Agriculture and Rural Health Development, Vietnam

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

 

Chantanee Buranathai, DVM, PhD, Chief, Emerging and Exotic Animal Disease Section, Division of Veterinary Epidemiology, Department of Livestock Development, Thailand

10:15–10:40

Strategies for Preventing and Controlling Avian Influenza and its Transmission within the Bird and Animal Population

Dewan Sibartie, DVM, PhD, Scientific and Technical Department, Office International des Épizooties (OIE)

10:40–11:45

Discussion Panel: Guus Koch, DVM, Central Institute for Animal Disease Control, Wageningen University and Research Centre, Lelystad, The Netherlands

David Swayne, DVM, PhD, Laboratory Director and Research Leader, Southeast Poultry Research Laboratory, U.S. Department of Agriculture

Carol Cardona, DVM, PhD, Poultry Extension Veterinarian and Assistant Professor, Veterinary Extension, University of California-Davis

Laurence S. Tiley, PhD, Lecturer in Molecular Virology, Centre for Veterinary Science, University of Cambridge, United Kingdom

11:45

Break

12:00–12:25

Enhancing Influenza Surveillance: From the Global to the Local Perspective

Nancy J. Cox, PhD, Chief, Influenza Branch, Centers for Disease Control and Prevention and Director, WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza

12:25–1:00

Discussion

1:00

Lunch

Session VI: Panel Discussion—Priorities for Improving Preparedness

Moderator: Frederick Sparling, MD, Professor of Medicine, Microbiology, and Immunology, University of North Carolina

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

2:00–2:20

Pandemic Influenza and Mortality: Past Evidence and Projections for the Future

Lone Simonsen, PhD, Office of Global Affairs, National Institute of Allergy and Infectious Diseases, National Institutes of Health

2:20–2:40

Increasing Awareness and Uptake of Influenza Immunization

Glen Nowak, PhD, Office of Health Communications, National Immunization Program, CDC

2:40–3:00

Public Communication Strategies to Remedy Panic in a Pandemic

Monica Schoch-Spana, PhD, Center for Biosecurity, University of Pittsburgh Medical Center

3:00–3:20

Preparing the Legal System for Pandemic Influenza

Larry Gostin, JD, Center on Law and the Public’s Health, Georgetown University

3:20

Open Discussion

5:00

Closing Remarks/Adjourn

DISCUSSANTS-AT-LARGE

David Bell, MD, Senior Medical Officer, Office of the Director, National Center for Infectious Diseases, Centers for Disease Control and Prevention

Timothy Booth, MD, Director, Viral Diseases Division, National Microbiology Laboratory, Health Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Ontario

Kathy Coelingh, PhD, Senior Director of Scientific and Regulatory Affairs, MedImmune Vaccines, Mountain View, CA

Jack Croddy, Senior Advisor, Office of Diplomacy, U.S. Department of State

William M. Egan, PhD, Acting Director, Office of Vaccines, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration

Geoffrey Evans, MD, Medical Officer, Vaccine Injury Compensation Program, Health Resources and Services Administration, U.S. Department of Health and Human Services

Harold Foster, Deputy Director, Office of International Health Affairs, U.S. Department of State

Adolfo Garcia–Sastre, PhD, Associate Professor, Department of Microbiology, Mount Sinai School of Medicine, New York

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

Kathleen F. Gensheimer, MD, MPH, State Epidemiologist and Director, Medical Epidemiology Section, Maine Bureau of Health, Department of Human Services

Robert A. Heckert, DVM, PhD, National Program Leader, Animal Health, Agricultural Research Service, U.S. Department of Agriculture

Charles Hoke, MD, Walter Reed Army Institute of Research, U.S. Army Medical Research and Materiel Command

Yanzhong Huang, PhD, Assistant Professor and Director, Center for Global Health Studies, John C. Whitehead School of Diplomacy and International Relations, Seton Hall University

Dominick Iacuzio, F. Hoffman La-Roche

George Kemble, PhD, Senior Director of Research, MedImmune Vaccines, Mountain View, CA

Richard F. Kingham, JD, Partner, Covington and Burling, Washington, DC, and London

David J. Lipman, MD, Director, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health

Nina Marano, DVM, MPH, Dipl. ACVPM, Associate Director for Veterinary Medicine and Public Health National Center for Infectious Diseases, Centers for Disease Control and Prevention

James T. Matthews, PhD, Director, External Research and Development, Aventis Pasteur Group, Swiftwater, PA

Michael McGuire, F. Hoffman La-Roche

Mark Miller, MD, Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health

Arnold Monto, MD, Professor of Epidemiology, Director of the University of Michigan Bioterrorism Preparedness Initiative, School of Public Health, University of Michigan, Ann Arbor

Stuart Nightingale, MD, Senior Advisor, Office of the Assistant Secretary for Public Health Emergency Preparedness, U.S. Department of Health and Human Services

Tara O’Toole, MD, MPH, Center for Biosecurity, University of Pittsburgh Medical Center

Michael Perdue, PhD, Research Leader, Environmental Microbial Safety Laboratory, Animal & Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture

Sara Radcliffe, MPH, Director, Science Policy and Bioethics, Biotechnology Industry Organization

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×

Stewart Simonson, Assistant Secretary for Public Health Emergency Preparedness, Office of Public Health Emergency Preparedness, U.S. Department of Health and Human Services

Eve Slater, MD, former Assistant Secretary for Health, U.S. Department of Health and Human Services

Rick Smith, MD, Office of Special Programs, Healthcare Emergency Preparedness, Health Resources and Services Administration, U.S. Department of Health and Human Services

Kanta Subbarao, MD, Senior Investigator, Respiratory Viruses Section, National Institute for Allergy and Infectious Diseases, National Institutes of Health

Susan C. Trock, DVM, MPH, DACVPM (Epi), New York State Department of Agriculture and Markets

Clara Witt, VMD, MPH, Global Emerging Infections Surveillance System, U.S. Department of Defense

Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page373
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page374
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page375
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page376
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page377
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page378
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page379
Suggested Citation:"Appendix A: Pandemic Influenza: Assessing Capabilities for Prevention and Response." Institute of Medicine. 2005. The Threat of Pandemic Influenza: Are We Ready? Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11150.
×
Page380
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Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns.

The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

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