Appendix C
Commercially Available Radiopharmaceuticals
Radiopharmaceutical |
Trade Name |
Primary Uses |
Carbon-14 Urea |
Pytest |
Detection of H Pylori |
Cobalt-57 cyanocobalamin |
Rubratope |
Schilling test |
Chromium-51 sodium chromate |
Chromitope (Bracco) Mallinckrodt Cr-51 |
Labeling red blood cells (RBC) |
Fluorine-18-FDG |
|
Positron emission tomography (PET) imaging |
Gallium-67 |
Neoscan (GE) DuPont Ga-67 Mallinckrodt Ga-67 |
Soft-tissue tumor and inflammatory process imaging |
Indium-111 chloride |
Indiclor (Nycomed) Mallinckrodt In-111Cl |
Labeling monoclonal antibodies and peptides (OncoScint & Octreoscan) |
Indium-111 pentetate (DTPA) |
Indium DTPA In-111 |
Imaging of cerebrospinal fluid kinetics |
Indium-111 oxyquinoline (oxine) |
Indium-111 oxine |
Labeling leukocytes and platelets |
Indium-111 Capromab pendetide |
ProstaScint |
Monoclonal antibody for imaging prostate cancer |
Radiopharmaceutical |
Trade Name |
Primary Uses |
Indium-111 pentetreotide |
Octreoscan |
Imaging neuroendocrine tumors |
I-123 sodium iodide |
Mallinckrodt Amersham |
Thyroid imaging and uptake |
I-125 iothalamate |
Glofil |
Measurement of glomerular filtration |
I-125 human serum albumin (RISA) |
Isojex |
Plasma volume determinations |
I-131sodium iodide |
Iodotope (Bracco) CIS - I-131 Mallinckrodt I-131Soln Mallinckrodt I-131 Therapy Caps Mallinckrodt I-131 Diagnostic Caps |
Thyroid uptake, imaging, and therapy |
Tositumomab & Iodine I-131 Tositumomab |
Bexxar |
Treatment of non-Hodgkin’s lymphoma |
I-131 iodomethylnorcholesterol (NP-59) |
(University of Michigan) |
Adrenal imaging |
I-131 metaiodobenzylguanidine (MIBG) |
I-131 MIBG |
Imaging pheochromocytomas and neuroblastomas |
P-32 chromic phosphate |
Phosphocol P32 |
Therapy for intracavitary malignancies |
P-32 sodium phosphate |
|
Therapy for polycythemia vera |
Rubidium-82 (from Sr-82/Rb-82 generator) |
Cardio-Gen-82 |
PET imaging |
Samarium-153 Lexidronam (Sm-153 EDTMP) |
Quadramet |
Palliative treatment of bone pain of skeletal metastases |
Strontium-89 |
Metastron |
Palliative treatment of bone pain of skeletal metastases |
Radiopharmaceutical |
Trade Name |
Primary Uses |
Tc-99m pertechnetate Generators |
DuPont Mallinckrodt DTE Mallinckrodt FM Amersham |
Imaging thyroid, salivary glands, ectopic gastric mucosa, parathyroid glands, dacryocystography, cystography |
Tc-99m Apcitide |
AcuTect |
Peptide imaging of deep vein thrombosis |
Tc-99m bicisate (ECD) |
Neurolite |
Cerebral perfusion imaging |
Tc-99m disofenin (DISIDA) |
Hepatolite-CIS |
Hepatobiliary imaging |
Tc-99m exametazine (HMPAO) |
Ceretec |
Cerebral perfusion imaging |
Tc-99m Gluceptate |
Draximage Mallinckrodt |
Renal imaging |
Tc-99m human serum albumin (HSA) |
|
Imaging cardiac chambers |
Tc-99m macroaggregated albumin (MAA) |
Pulmolite - CIS Macrotec (Bracco) Technescan MAA (Mallinckrodt) Draximage Amersham MAA |
Pulmonary perfusion |
Tc-99m Mebrofenin |
Choletec |
Hepatobiliary imaging |
Tc-99m Medronate (MDP) |
Bracco Osteolite - CIS Draximage Mallinckrodt Amersham |
Bone imaging |
Tc-99m Mertiatide |
Technescan MAG3 |
Renal imaging |
Tc-99m Oxidronate (HDP) |
Mallinckrodt HDP |
Bone imaging |
Tc-99m Pentetate (DTPA) |
Techneplex (Bracco) CIS-AN DTPA CIS-DTPA Draximage DTPA Mallinckrodt DTPA Nycomed DTPA |
Renal imaging and function studies; Radioaerosol ventilation imaging |
Radiopharmaceutical |
Trade Name |
Primary Uses |
Tc-99m Pyrophosphate (PYP) |
Phosphotec (Bracco) Pyrolite-CIS Pyro-CIS Technescan PYP Amersham PYP |
Avid infarct imaging; in vivo RBC labeling |
Tc-99m red blood cells |
Ultratag |
Imaging gastrointestinal (GI) bleeds, cardiac chambers |
Tc-99m Sestamibi |
Cardiolite Miraluma |
Myocardial perfusion imaging Breast tumor imaging |
Tc-99m Succimer (DMSA) |
Amersham DMSA |
Renal imaging |
Tc-99m Sulfur Colloid (SC) |
CIS-Sulfur Colloid Nycomed - SC |
Imaging liver/spleen, gastric emptying, GI bleeds |
Tc-99m Tetrofosmin |
Myoview |
Myocardial perfusion imaging |
Thallium-201 |
DuPont Mallinckrodt Amersham |
Myocardial perfusion imaging; Parathyroid and tumor imaging |
Y-90 Ibitumomab Tiuxetan |
Zevalin |
non-Hodgkin’s lymphoma |
Xenon-133 |
DuPont Xenon Mallinckrodt Xenon Amersham Xenon |
Pulmonary ventilation imaging |
Interventional Agents |
Trade Name |
Use in nuclear medicine |
ACD solution (anticoagulant acid Acitrate dextrose) |
ACD Solution Modified |
Anticoagulant used in blood labeling |
Adenosine |
Adenoscan |
Pharmacologic stress |
Ascorbic acid |
Ascorbic acid |
RBC labeling and HDP preparation |
I.V. Dipyridamole |
I.V. Persantine |
Pharmacologic stress |
Sincalide |
Kinevac |
Gallbladder ejection fraction studies |
SOURCE: University of Arkansas for Medical Sciences (http://nuclearpharmacy.uams.edu/resources/PackageInserts.asp). |