National Academies Press: OpenBook

Medical Isotope Production Without Highly Enriched Uranium (2009)

Chapter: Appendix H: Acronyms

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Suggested Citation:"Appendix H: Acronyms." National Research Council. 2009. Medical Isotope Production Without Highly Enriched Uranium. Washington, DC: The National Academies Press. doi: 10.17226/12569.
Page 200
Suggested Citation:"Appendix H: Acronyms." National Research Council. 2009. Medical Isotope Production Without Highly Enriched Uranium. Washington, DC: The National Academies Press. doi: 10.17226/12569.
Page 201
Suggested Citation:"Appendix H: Acronyms." National Research Council. 2009. Medical Isotope Production Without Highly Enriched Uranium. Washington, DC: The National Academies Press. doi: 10.17226/12569.
Page 202

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Appendix H Acronyms ACCF American College of Cardiology Foundation ACRR Annular Core Research Reactor AECL Atomic Energy of Canada Limited AIPES Association of Imaging Producers and Equipment Suppliers ANL Argonne National Laboratory ANSTO Australian Nuclear Science and Technology Organisation ARI ANSTO Radiopharmaceuticals and Industrials ASNC American Society of Nuclear Cardiology ATR Advanced Test Reactor B&W Babcock & Wilcox BARC/BRIT Bhabha Atomic Research Centre/Board of Radiation and Isotope Technology BATAN Indonesian National Atomic Energy Agency BMS Bristol-Myers Squibb BR2 Belgian Reactor II CERCA Compagnie pour l’ Etude et la Réalisation de Combustibles Atomiques CFR Code of Federal Regulations CMR Chemistry and Metallurgy Research CMS Centers for Medicare & Medicaid Services CNEA Comisión Nactional de Energía Atómica CNSC Canadian Nuclear Safety Commission 200

APPENDIX H 201 CORAR Council on Radionuclides and Radiopharmaceuticals CRADA Cooperative Research and Development Agreement CRP Coordinated Research Project CT Computed tomography DIF Dedicated Isotope Facilities DMF Drug Master File DOE U.S. Department of Energy DOE-NNSA U.S. Department of Energy, National Nuclear Security Administration DOS U.S. Department of State EOB End of bombardment EOI Expression of interest ESFRI European Strategy Forum on Research Infrastructures ETRR-2 Egyptian Testing Research Reactor II FDA U.S. Food and Drug Administration FDG 2-deoxy-2-[18F] fluoro-D-glucose (also called fluordeoxyglucose) FISS Fissile solution storage FRM-II Forschungsneutronenquelle Heinz Maier-Leibnitz (German: Research Reactor Munich II) FRRSNF Foreign Research Reactor Spent Nuclear Fuel GE General Electric GTCC Greater-than-class C GTRI Global Threat Reduction Initiative HEU Highly enriched uranium HFETR-C High Flux Engineering Test Reactor- China HFIR High Flux Isotope Reactor HFR High Flux Reactor HIFAR High Flux Australian Reactor HLW High-level waste IAEA International Atomic Energy Agency INFCE International Nuclear Fuel Cycle Evaluation INL Idaho National Laboratory INVAP Investigaciones Aplicadas Sociedad del Estado IRE Institut National des Radioéléments KAERI Korea Atomic Energy Research Institute

202 APPENDIX H LEU Low enriched uranium LLW Low-leve waste MDP Methylene diphosphonate MIPS Medical Isotope Production System MIT Massachusetts Institute of Technology MNSR Miniature Neutron Source Reactor MOU Memorandum of understanding MRI Magnetic resonance imaging MTR Materials Test Reactor MURR Missouri University Research Reactor NBSR National Bureau of Standards Reactor NDA New Drug Application NECSA Nuclear Energy Corporation of South Africa NNSA National Nuclear Security Administration NPF New processing facility NRG Nuclear Research and Consultancy Group NRU National Research Universal (reactor) NTP Nuclear Technology Products OPAL Open Pool Australian Lightwater (reactor) OWR Omega West Reactor PET Positron emission tomography POLATOM Institute of Atomic Energy Radioisotope Centre R&D Research and development RERTR Reduced Enrichment for Research and Test Reactors RF Russian Federation RRRFR Russian Research Reactor Fuel Return sNDA Supplemental New Drug Application SPECT Single photon emission computed tomography SRS Savannah River site TCI Technology Commercialization International USNRC U.S. Nuclear Regulatory Commission USP United States Pharmacopeia

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This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel.

The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.


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