May 26, 2011
Keck Center, Room 109
500 Fifth Street, NW
Washington, DC 20001
BACKGROUND AND OVERVIEW
Session Objectives: Obtain a better understanding of the background to the study and the charge to the committee. Receive a briefing from NIH about existing areas of science where chimpanzee research is supported. Hear from stakeholders about the use of chimpanzees in research, as specifically related to the committee’s charge.
1:00 p.m. Welcome and Introductions
JOHN STOBO, Committee Chair
Senior Vice President
Health Sciences and Services
University of California System
1:10 p.m. Background and Charge to the Committee
SALLY ROCKEY
Deputy Director for Extramural Research
National Institutes of Health
1:30 p.m. Committee Discussion with Sponsor
JOHN STOBO, Committee Chair
Senior Vice President
Health Sciences and Services
University of California System
2:15 p.m. NIH-Supported Chimpanzee Biomedical Research
HAROLD WATSON
Deputy Director
Division of Comparative Medicine
National Center for Research Resources, NIH
2:35 p.m. Discussion with the Committee
2:45 p.m. BREAK
3:15 p.m. NIH-Supported Chimpanzee Behavioral Research
RICHARD NAKAMURA
Scientific Director
National Institute of Mental Health, NIH
3:35 p.m. Discussion with the Committee
3:45 p.m. Panel Discussion: Is there a continued need for chimpanzee research?
JOHN PIPPIN
Senior Medical and Research Adviser
Physicians Committee for Responsible Medicine
JARROD BAILEY
Science Director
New England Anti-Vivisection Society
KEVIN KREGEL
Professor, Departments of Integrative
Physiology and Radiation Oncology
University of Iowa
Chair, Animal Issues Committee
Federation of American Societies for Experimental Biology
4:15 p.m. Discussion with the Committee
4:45 p.m. ADJOURN
August 11, 2011
Keck Center, Room 100
500 Fifth Street, NW
Washington, DC 20001
Meeting Objectives:
• To obtain background data on the current use of chimpanzees in biomedical and behavioral research.
• To explore potential alternative models to chimpanzees.
• To seek public comment about the scientific need for chimpanzees in biomedical and behavioral research.
8:00 a.m. Welcome and Meeting Objectives
JEFFREY KAHN, Committee Chair
Director and Professor
Maas Family Endowed Chair in Bioethics
Center for Bioethics
University of Minnesota
SESSION I: THE CHIMPANZEE
Session Objectives: Understand chimpanzee behavior and genetics and their role in biomedical research. Compare chimpanzees both to other models and to humans. Explore the usefulness of the chimpanzee as a model for biomedical and behavioral research, specifically for understanding human diseases and disorders. Discuss what scientific alternatives exist should the chimpanzee no longer be an available model.
JAY KAPLAN, Session Chair
Professor of Pathology (Comparative Medicine), Translational Science and Anthropology
Wake Forest University Primate Center and Wake Forest Translational Science Institute
Wake Forest School of Medicine
8:10 a.m. Chimpanzee Behavior
FRANS DE WAAL
C.H. Candler Professor of Primate Behavior
Department of Psychology
Emory University
8:30 a.m. Chimpanzee Genetics
JEFFREY ROGERS
Associate Professor
Department of Molecular and Human Genetics
Baylor College of Medicine
8:50 a.m. Chimpanzee Biomedical Research
ROBERT PURCELL Chief,
Hepatitis Viruses Section
Laboratory of Infectious Diseases
National Institute of Allergy and Infectious Diseases
9:10 a.m. Panel Discussion with Committee
• What scientific alternatives exist should the chimpanzee no longer be an available model?
9:40 a.m. BREAK
SESSION II: BEHAVIORAL RESEARCH
Session Objective: Review current use of chimpanzees for behavioral research. Explore alternative models also used in this research area.
ROBERT SAPOLSKY, Session Chair
Professor of Biology, Neurology and Neurological Sciences
Stanford University
9:50 a.m. PANELISTS [15 min/talk]
Chimpanzee Social Behavior and Communication
WILLIAM HOPKINS
Professor
Department of Psychology
Agnes Scott College
Chimpanzee Learning and Memory
CHARLES MENZEL
Senior Research Scientist
Language Research Center
Georgia State University
Potential for Non-Human Primates in Behavioral Research
MARK MOSS
Professor and Chair
Department of Anatomy and Neurobiology
Boston University
Chimpanzee Research in Zoos and Sanctuaries
BRIAN HARE
Assistant Professor
Department of Evolutionary Anthropology
Duke University
10:50 a.m. Panel Discussion with Committee
• What scientific alternatives exist should the chimpanzee no longer be an available model?
• How long would it take for science to catch up if the chimpanzee were no longer available?
SESSION III: PUBLIC COMMENT
Session Objectives: Seek public comment from interested stakeholders about the continued and potential future need for chimpanzees in biomedical and behavioral research.
NOTE: To accommodate requests, speakers will be strictly limited to 3 minutes.
JEFFREY KAHN, Committee Chair
Director and Professor
Maas Family Endowed Chair in Bioethics Center for Bioethics
University of Minnesota
11:20 a.m. Public Comments
ALICE RA’ANAN
Director of Government Affairs and Science Policy
The American Physiological Society
ANNE DESCHAMPS
Science Policy Analyst
Federation of American Societies for Experimental Biology
JUSTIN GOODMAN
Associate Director
People for the Ethical Treatment of Animals
LAURA BONAR
Program Director
Animal Protection of New Mexico
STEPHEN ROSS
Assistant Director, Lester Fisher Center for the
Study and Conservation of Apes
Lincoln Park Zoo
RAIJA BETTAUER
Bettauer BioMed Research
PAMELA OSENKOWSKI
Director of Science Programs
National Anti-Vivisection Society
SUE LEARY
President
Alternatives Research & Development Foundation
THEODORA CAPALDO
President/Executive Director
New England Anti-Vivisection Society/Project Release & Restitution
ERIC KLEIMAN
Research Director
In Defense of Animals
RYAN MERKLEY
Associate Director of Research Policy
Physicians Committee for Responsible Medicine
MATTHEW BAILEY
Vice President
National Association for Biomedical Research
JOSEPH ERWIN
Consulting Primatologist
KATHLEEN CONLEE
Director of Program Management
The Humane Society of the United States
BETH CATALDO
Director
Cetacean Society USA
CATHY LISS
President
Animal Welfare Institute
DAVID DEGRAZIA
Professor of Philosophy
George Washington University
C. JAMES MAHONEY
Research Professor
New York University School of Medicine
12:20 p.m. LUNCH
SPECIAL LECTURE
1:00 p.m. Chimpanzees in Biomedical and Behavioral Research
JANE GOODALL (via video conference)
Founder
Jane Goodall Institute
1:30 p.m. Discussion with Committee
SESSION IV: HEPATITIS
Session Objectives: Review the role of chimpanzees in hepatitis research. Explore alternative models also used in this research area.
DIANE GRIFFIN, Session Chair
Professor and Chair
Department of Molecular Microbiology and Immunology
Johns Hopkins Bloomberg School of Public Health
1:40 p.m. PANELISTS [15 min/talk]
The Current State of Hepatitis Research
ROBERT LANFORD
Scientist
Department of Virology and Immunology
Texas Biomedical Research Institute
The Next Drug for Hepatitis B and C
CHRISTOPHER WALKER
Professor of Pediatrics
Nationwide Children’s Hospital
The Ohio State University
Cellular and Molecular Technique Advances in Hepatitis Research
STANLEY LEMON
Professor of Medicine
Division of Infectious Diseases
University of North Carolina School of Medicine
Humanized Mice for the Study of Human Infectious Diseases
ALEXANDER PLOSS
Research Assistant Professor
Laboratory of Virology and Infectious Disease
The Rockefeller University
From Chimpanzee to Human—Translational Research in Viral Hepatitis
EUGENE SCHIFF
Leonard Miller Professor of Medicine
Director, Schiff Liver Institute/Center for Liver Disease
University of Miami Medical School
2:55 p.m. Panel Discussion with Committee
• What scientific alternatives exist should the chimpanzee no longer be an available model?
• How long would it take for science to catch up if the chimpanzee were no longer available?
3:40 p.m. BREAK
SESSION V: INFECTIOUS DISEASES
Session Objectives: Review the role of chimpanzees in infectious disease research. Explore alternative models also used in this research area.
JOHN BARTLETT, Session Chair
Professor
Department of Medicine
Johns Hopkins University School of Medicine
4:00 p.m. PANELISTS [15 min/talk]
The Role of Chimpanzees in HIV Research
NANCY HAIGWOOD
Professor of Microbiology and Immunology
Director
Oregon National Primate Research Center
The Role of Chimpanzees in RSV Research
PETER COLLINS
Director
RNA Viruses Section
National Institute of Allergy and Infectious Diseases
Current Experimental Models for Malaria Vaccine Development
ANN-MARIE CRUZ
Program Officer, Research and Development
PATH Malaria Vaccine Initiative
Monoclonal Antibody Therapeutics
THERESA REYNOLDS
Director
Safety Assessment
Genentech
Alternative Models for Infectious Disease Research
ROBERT HAMATAKE
Director of HCV Biology
GlaxoSmithKline
5:15 p.m. Panel Discussion with Committee
• What scientific alternatives exist should the chimpanzee no longer be an available model?
• How long would it take for science to catch up if the chimpanzee were no longer available?
6:00 p.m. ADJOURN
August 12, 2011
Keck Center, Room 100
500 Fifth Street, NW
Washington, DC 20001
Meeting Objectives:
• To obtain background data on the current use of chimpanzees in biomedical and behavioral research
• To explore potential alternative models to chimpanzees
• To seek public comment about the scientific need for chimpanzees in biomedical and behavioral research
SESSION VI: POTENTIAL FUTURE NEEDS
Session Objectives: Explore potential future needs for chimpanzees in biomedical and behavioral research. Consider emerging threats and novel technologies.
EDWARD HARLOW, Session Chair
Special Assistant to the Director
National Cancer Institute
8:30 a.m. PANELISTS [15 min/talk]
Surveying the Future of Chimpanzee Research
THOMAS J. ROWELL
Director
New Iberia Research Center
University of Louisiana at Lafayettte
Is Chimpanzee Research Critical to the Health Security of the United States?
JOSEPH BIELITZKI
Associate Director
Office of Research and Commercialization
University of Central Florida
The Role of Chimpanzees in Biodefense Research—DoD Perspective
JAMES SWEARENGEN
Director (retired)
Comparative Medicine Veterinarian
National Biodefense Analysis and Countermeasures Center
The Role of Chimpanzees in Biodefense Research—NIH Perspective
MICHAEL KURILLA
Director
Office of Biodefense Research Affairs
National Institutes of Health
9:45 a.m. Discussion with the Committee
• In the event of a public health emergency, what would the consequences be if there were no chimpanzees available for biomedical research?
• What would the impact be if chimpanzees were unavailable for testing during drug development and research?
• How long would it take for science to catch up if the chimpanzee were no longer available?
10:45 a.m. ADJOURN
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