Identifying and Reducing Environmental Health Risks of Chemicals in Our Society: Workshop Summary (2014)

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B Agenda November 7–8, 2013 Room 100 Keck Center of the National Academy of Sciences 500 Fifth Street, NW, Washington, DC November 7, 2013 9:00 a.m. Welcome Frank Loy, LL.B. Roundtable Chair Session 1: Background and Framing Objectives: • Provide an overview of chemical exposures from pesticides, to cosmetics, to food, and to industrial processes and explain why the workshop will focus on new and existing industrial chemicals. • Briefly highlight what is known now that was not known 20 years ago about the links between chemical hazards and human health. • Describe a public health approach to industrial chemical assessments based on identifying sentinel health events, delineating a cascade of preventive interventions (primary, secondary, and tertiary), and using public health surveillance to monitor and improve the system. 9:05 a.m. Overview of Our Daily Exposure to Chemicals and the Need to Discuss Industrial Chemical Assessments Lynn Goldman, M.D., M.P.H. Roundtable Vice-Chair 149 

150 ENVIRONMENTAL HEALTH RISKS OF CHEMICALS Dean, School of Public Health and Health Services George Washington University 9:20 a.m. Public Health Approach to Industrial Chemical Assessments William E. Halperin, Dr.P.H., M.D., M.P.H. Chair and Professor Department of Preventive Medicine and Community Health New Jersey Medical School Professor and Associate Dean Rutgers School of Public Health 9:35 a.m. National Conversation on Public Health and Chemical Exposures Action Agenda Nsedu Obot Witherspoon, M.P.H. Co-Chair, National Conversation Leadership Council Executive Director Children’s Environmental Health Network 9:50 a.m. Discussion 10:20 a.m. Break (15 minutes) Session 2: Current Programs for Safeguarding the Public from Potential Health Risks of Industrial Chemicals: Successes and Areas for Improvement Objectives: • Provide an overview of what is working and where gaps may be present in a variety of existing regulations and industrial chemical safety programs. • Explain that the manufacturer of a chemical is primarily informed about its toxicity information but may not know specifically how the chemical will be used, whereas the processer of the chemical is primarily informed about its uses and exposure information (among workers and consumers) and may use the chemical in ways the manufacturer never considered. • Propose suggestions for how to improve the effectiveness and efficiency of regulatory programs. 

APPENDIX B 151 Moderator: Dennis Devlin, Ph.D., Environmental Health Advisor, ExxonMobil Corporation 10:35 a.m. Global Perspective Canice Nolan, Ph.D. Senior Coordinator for Global Health European Commission Directorate General for Health and Consumers 10:50 a.m. U.S. Federal Perspective Wendy Cleland-Hamnett, J.D. Director, Office of Pollution Prevention and Toxics Office of Chemical Safety and Pollution Prevention U.S. Environmental Protection Agency 11:05 a.m. NGO Perspective Richard Denison, Ph.D. Senior Scientist Environmental Defense Fund 11:20 a.m. Industry Perspective Michael P. Walls, J.D. Vice President of Regulatory and Technical Affairs American Chemistry Council 11:35 a.m. Discussion 12:20 p.m. Lunch Break (60 minutes) Session 3: Models for Environmental Risk Assessment and Exposure Science Objectives: • Provide brief summaries of key meetings and reports that have been held and released on environmental risk assessment and exposure science. • Comment on where all this research may be leading: o How will this inform work to improve policy, assessment, and action strategies related to industrial chemical safety programs? 

152 ENVIRONMENTAL HEALTH RISKS OF CHEMICALS o What more needs to be done to allow for better modeling, monitoring, and measurement of industrial chemical exposures? • Present a status update of a new National Research Council committee tasked to develop a decision framework for evaluating potentially safer chemical substitutions. Moderator: Susan Santos, Ph.D., M.S., Assistant Professor, Rutgers School of Public Health 1:20 p.m. Science and Decisions: Advancing Risk Assessment (report released in 2009) John M. Balbus, M.D., M.P.H. Senior Advisor for Public Health National Institute of Environmental Health Sciences 1:35 p.m. Exposure Science in the 21st Century: A Vision and a Strategy (report released in 2012) Paul Gilman, Ph.D. Senior Vice President and Chief Sustainability Officer Covanta Energy Corporation 1:50 p.m. Advancing the Next Generation (NexGen) of Risk Assessment: Public Dialogue Conference (meeting held in 2011) Ila Cote, Ph.D., DABT Senior Science Advisor National Center for Environmental Assessment Office of Research and Development U.S. Environmental Protection Agency 2:05 p.m. Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Government and Industry Decisions (status update) Marilee Shelton-Davenport, Ph.D. Senior Program Officer Division on Earth and Life Studies The National Academies 2:20 p.m. Panel Discussion 

APPENDIX B 153 3:05 p.m. Break (20 minutes) Session 4: Improved Approaches to Chemical Prioritization for Risk Assessment and Risk Management Objectives: • Build on the presentations in Session 2 that highlighted existing chemical prioritization frameworks from a variety of settings. • Discuss better approaches to chemical prioritization (forward looking) to help inform targeted testing schemes and improve risk assessment and management strategies. Moderator: Andrew Maguire, Ph.D., Roundtable Member 3:25 p.m. Bench-Level Scientific Innovation Richard Judson, Ph.D. National Center for Computational Toxicology Office of Research and Development U.S. Environmental Protection Agency 3:40 p.m. State-Led Innovation: California Gina Soloman, M.D., M.P.H. Deputy Secretary for Science and Health California Environmental Protection Agency 3:55 p.m. Country-Level Innovation: Government of Canada Heather Patterson Assessment Strategies Division Existing Substances Risk Assessment Bureau Safe Environments Directorate Health Canada 4:10 p.m. Industry Innovation: American Chemistry Council Christina Franz, J.D. Senior Director, Regulatory and Technical Affairs American Chemistry Council 4:25 p.m. Discussion 5:30 p.m. Adjourn for the Day 

154 ENVIRONMENTAL HEALTH RISKS OF CHEMICALS November 8, 2013 8:40 a.m. Welcome Back Lynn Goldman, M.D., M.P.H. Roundtable Vice-Chair Session 5: Actions to Reduce the Risk of Chemicals in Our Society Objectives: • Discuss the topic of prevention from an environmental stewardship approach. • Cover broad concepts of sustainability and economics, and more technical issues of developing safer chemical alternatives. • Provide industry examples of voluntary efforts to reduce use of chemicals in consumer products and internal decision making that led to these outcomes. Moderator: Al McGartland, Ph.D., Director of the National Center for Environmental Economics, U.S. EPA 8:45 a.m. NIEHS Sustainability and Green Programs Trisha Castranio Sustainability Analyst National Institute of Environmental Health Sciences 9:00 a.m. Johnson & Johnson Case Study Zephanie Jordan Vice President Global Regulatory Affairs and Product Stewardship Johnson & Johnson 9:15 a.m. The Dow Chemical Company Case Study Connie Deford Director, Product Sustainability and Compliance The Dow Chemical Company 9:30 a.m. American Chemical Society Green Chemistry Institute® Case Study David J. C. Constable, Ph.D. Director American Chemical Society Green Chemistry Institute® 

APPENDIX B 155 9:45 a.m. SIN (Substitute It Now!) List and GreenScreen® Case Study Beverley Thorpe Consulting Co-Director, Communications and Advocacy Clean Production Action 10:00 a.m. Massachusetts Toxics Use Reduction Institute (TURI) Case Study Liz Harriman, M.S. Deputy Director, Toxic Use Reduction Institute University of Massachusetts, Lowell 10:15 a.m. Bullitt Center Case Study Joseph David Sustainability Program Manager Point 32 10:30 a.m. Discussion 11:15 a.m. Break (15 minutes) Session 6: Reflections on the Workshop and Concluding Remarks Objective: • Provide a moderated panel discussion to synthesize previous presentations and discussions (focusing on Sessions 1, 2, 4, and 5) and thoughts on possible next steps. Moderator: Frank Loy, Roundtable Chair 11:30 a.m. Panel Discussion Kimberly Thigpen Tart (synthesis of Session 1) Program Analyst, Office of Policy, Planning, and Evaluation National Institute of Environmental Health Sciences Bernard D. Goldstein, M.D. (synthesis of Session 2) Professor Emeritus of Environmental and Occupational Health University of Pittsburgh Graduate School of Public Health 

156 ENVIRONMENTAL HEALTH RISKS OF CHEMICALS Harold Zenick, Ph.D. (synthesis of Session 4) Director, National Health and Environmental Effects Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Lynn Goldman, M.D., M.P.H. (synthesis of Session 5) Roundtable Vice-Chair Dean, School of Public Health and Health Services George Washington University 12:10 p.m. Discussion 12:30 p.m. Adjourn