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FOREWORD The following statements were prepared by the Food Protection Committee in accord with its objective "to develop guiding princi- ples and standardized procedures essential to safeguard food". The first two statements were released in mimeographed form in June 1951. The third statement is published for the first time herein. All have had the endorsement of the Food and Nutrition Board, and have had the benefit of constructive suggestions from members of the liaison panel. In December 1951, the Committee published a statement entitled "Use of Chemical Additives in Foods" which attempted to eluci- date the facts about chemicals occurring naturally in foods and those added incidentally during production or processing. The precautions taken by governmental agencies and industry to insure a safe and wholesome food supply were outlined therein. The three statements in the present publication go one step fur- ther in depicting what the Committee believes to represent the essential considerations necessary to judge the "safety" for use of chemicals in foods.