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Refinements to the Methods for Developing Spacecraft Exposure Guidelines (2016)

Chapter: Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines

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Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
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Appendix A

Biographical Information on the Committee on Spacecraft Exposure Guidelines

Edward C. Bishop is a risk management consultant for HDR, Inc. He has diverse experience in industrial hygiene, environmental compliance, emergency response, and risk assessment. He had a 20-year career in the US Air Force, in which he held a number of positions, including senior bioenvironmental engineering program manager in the Office of the Air Force Surgeon General. In that position, he developed and managed occupational health, industrial hygiene, and environmental protection programs worldwide. Dr. Bishop has served on several committees of the National Academies of Sciences, Engineering, and Medicine, including service as chair of the Committee on Acute Exposure Guideline Levels. He is currently a member of the Committee on Chemical Demilitarization. He received his MS in engineering from the University of California, Los Angeles, and his PhD in environmental health sciences from the University of California, Berkeley.

Terry Gordon is a professor in the Department of Environmental Medicine at the New York University School of Medicine. He uses both human and animal experimental models to study the genetic susceptibility underlying the adverse pulmonary and cardiac effects of environmental and occupational air pollutants, such as ozone, beryllium, and nanoparticles. Dr. Gordon is chair of the Threshold Limit Value – Chemical Substances Committee of the American Conference of Governmental Industrial Hygienists and is a former president of the Inhalation Specialty Section of the Society of Toxicology. He received his MS in toxicology from the University of Michigan and his PhD in toxicology from the Massachusetts Institute of Technology.

Bernard A. Harris, Jr., is chief executive officer and managing partner of Vesalius Ventures, a venture capital firm that supports and invests in early to mid-stage health care technologies and companies. He is a former astronaut, who has logged more than 438 hours in space, and conducted the first telemedicine conference from space with the Mayo Clinic. He also worked for NASA for 10 years, conducting research in musculoskeletal physiology and disuse osteoporo-

Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×

sis. He led the Exercise Countermeasure Project, which involved clinical investigations into physiological space adaptation and the development of in-flight medical devices to extend the duration of astronaut stays in space. Dr. Harris is a former vice president and chief scientist of SPACEHAB, Inc., a venture-backed innovative space commercialization company, and a former vice president of business development for Space Media, Inc., an informatics company. He received an MD from Texas Tech University School of Medicine, an MMS from the University of Texas Medical Branch-Galveston, and an MBA from the University of Houston, and trained in internal medicine at the Mayo Clinic.

Terrance J. Kavanagh is a professor in the Department of Environmental and Occupational Health Sciences and adjunct professor of pulmonary and critical care medicine at the University of Washington (UW). He currently serves as director of the UW Center for Ecogenetics and Environmental Health, and Director of the UW Nanotoxicology Center. He is board certified in toxicology, with expertise in animal models, analytical cytology, in vitro toxicology, and gene-environment interactions. His areas of research interest include glutathione metabolism, free radical biology, oxidative stress biomarkers, toxicogenomics, systems genetics, and nanotoxicology. Dr. Kavanagh is a former president of the Mechanisms Specialty Section of the Society of Toxicology and of the Pacific Northwest Association of Toxicologists. He received his MS in physiology and PhD in environmental toxicology and genetics from Michigan State University.

Margaret M. MacDonell is a program manager in the Environmental Science Division of Argonne National Laboratory. Professional interests include integrated health impact analyses and environmental sustainability; environmental fate, exposure, and cumulative risk evaluations for multiple stressors, including chemical mixtures, nanomaterials, and other hazards (including those related to energy development); and community involvement for environmental health protection. Dr. MacDonell has conducted health risk analyses at legacy waste sites for the US Department of Energy and Army Corps of Engineers; developed risk training workshops for practitioners and managers; and collaborated with Environmental Protection Agency (EPA) Centers on cumulative risk assessment and acute and short-term exposure advisories for chemical, radiological, and biological contaminants. She has served on several Academies committees, including the Committee on Acute Exposure Guideline Levels and the Committee to Review the IRIS Process, and currently serves on the Committee on Toxicology. Dr. MacDonell received her MS in environmental health engineering from Notre Dame and her PhD in environmental health engineering from Northwestern University.

Martin A. Philbert is dean of the University of Michigan School of Public Health, and is a professor of toxicology. His research interests include experimental neuropathology, nitro compound–induced encephalopathies, mitochondrial mechanisms in non-neuronal cell death, and nanostructure-based imaging

Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×

and treatment of tumors of malignant gliomas. He is currently involved in developing magnetically responsive optical nanoprobes and systems for the Air Force. Dr. Philbert received his PhD in neurochemistry and experimental neuropathology from London University. He was elected to the Institute of Medicine in 2012.

Kenneth R. Still is a retired US Navy Captain in the Medical Service Corps. He served as the senior director of safety and occupational health for the Commander of the US Pacific Fleet, Pearl Harbor, Hawaii, as well as the officer-in-charge of the Navy’s Toxicology Research Laboratory Program in Dayton, Ohio. He is currently an adjunct assistant professor at Portland State University in the School of Community Health and participates in the Oregon Masters of Public Health program; he teaches both graduate and undergraduate courses in environmental health. Dr. Still is also the scientific director and senior toxicology consultant for Occupational Toxicology Associates, Inc., which provides consulting services for several Department of Defense programs. His research interests include human health risk assessment, exposure assessment, and regulatory and mechanistic toxicology. Dr. Still was a member the Academies Committee on Acute Exposure Guideline Levels and the Committee on Shipboard Hazard and Defense II, and currently serves on the Committee on Toxicology. He received his PhD in physiological ecology from Oklahoma State University. He is a fellow of the Academy of Toxicological Sciences and the American Industrial Hygiene Association, and is a certified industrial hygienist.

Joyce S. Tsuji is a principal scientist at Exponent, where she is involved in assessing health risks associated with substances in the environment, foods, consumer products, medical devices, and personal care products in the United States and internationally for industry, trade associations, the federal government, state agencies, municipalities, and private citizens. Her work has also involved environmental exposure studies and community programs involving health education and biomonitoring for populations potentially exposed to chemicals in the environment, including soil, water, and food-chain exposures. Dr. Tsuji is a board-certified toxicologist and a fellow of the Academy of Toxicological Sciences. She has served on expert committees for EPA, the US Army, and the state of Washington. She is currently a member of the Academies Board on Environmental Studies and Toxicology and the Committee on the Assessment of the Department of Veterans Affairs Airborne Hazards and Open Burn Pit Registry – Phase 1. Dr. Tsuji received a PhD focused on physiological ecology from the Department of Zoology at the University of Washington.

Carol S. Wood is a staff scientist in the Environmental Science Division of Oak Ridge National Laboratory. She has more than 20 years of experience as a toxicologist at Oak Ridge National Laboratory with extensive work in risk assessment for inhalation/pulmonary and oral toxicity of heavy metals and pesticides. She has worked on Acute Exposure Guideline Levels and Provisional Advisory

Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×

Levels, in which health-based exposure levels are developed for priority toxic chemicals. These projects often use toxicokinetic data and physiologically based pharmacokinetic models for extrapolation from animals to humans. Dr. Wood is on the Board of Directors of the American Board of Toxicology. At the request of the EPA, she wrote the guidance document “Standard Evaluation Procedure for Developmental Neurotoxicity Studies” and reviewed numerous submissions of testing and positive control neurotoxicity data. Her research experience and interests include developmental, reproductive, and neurotoxic outcomes from exposure to environmental contaminants. She is certified in general toxicology by the American Board of Toxicology. She served on the Institute of Medicine Committee on the Review of Clinical Guidance for the Care of Health Conditions Identified by the Camp Lejeune Legislation. Dr. Wood received her PhD in toxicology from Oregon State University.

Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×
Page 44
Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×
Page 45
Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×
Page 46
Suggested Citation:"Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
×
Page 47
Next: Appendix B: Example Report Outlines for Future SMAC and SWEG Documents »
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 Refinements to the Methods for Developing Spacecraft Exposure Guidelines
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Human spaceflight is inherently risky, with numerous potential hazards posed at each phase of a mission. Potential health risks during spaceflights include short-term health consequences from being in microgravity, as well as long-term health consequences that arise, or continue, months or years after a flight. Additional health considerations are risks posed by exposure to environmental contaminants onboard spacecraft. Because the International Space Station and spacecraft are closed environments that require recirculation of air and water supplies, some contamination of the air and water will occur. Even with onboard air and water purification systems, chemicals will accumulate in the air and water as they recirculate or are recycled onboard. Therefore, it is necessary for the National Aeronautics and Space Administration (NASA) to identify hazardous contaminants and determine exposure levels that are not expected to pose a health risk to astronauts.

NASA uses spacecraft maximum allowance concentrations (SMACs) and spacecraft water exposure guidelines (SWEGs) to provide guidance on acceptable exposures to air and water contaminants during normal operations and emergency situations. Refinements to the Methods for Developing Spacecraft Exposure Guidelines updates the methods for establishing SMACs and SWEGs and assists NASA with identifying chemicals that need updated SMACs or SWEGs and new chemicals for which these guidelines should be developed.

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