SELECTED HEALTH
CONDITIONS AND
LIKELIHOOD OF
IMPROVEMENT WITH
TREATMENT
Committee on Identifying Disabling Medical Conditions
Likely to Improve with Treatment
Board on Health Care Services
Health and Medicine Division
A Consensus Study Report of
THE NATIONAL ACADEMIES PRESS
Washington, DC
www.nap.edu
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001
This activity was supported by a contract between the National Academy of Sciences and the U.S. Social Security Administration (Contract No. 28321318D00060015). Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.
International Standard Book Number-13: 978-0-309-67095-1
International Standard Book Number-10: 0-309-67095-0
Digital Object Identifier: https://doi.org/10.17226/25662
Library of Congress Control Number: 2020934945
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Printed in the United States of America
Suggested citation: National Academies of Sciences, Engineering, and Medicine. 2020. Selected health conditions and likelihood of improvement with treatment. Washington, DC: The National Academies Press. https://doi.org/10.17226/25662.
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COMMITTEE ON IDENTIFYING DISABLING MEDICAL CONDITIONS LIKELY TO IMPROVE WITH TREATMENT
JUDITH GREEN-McKENZIE (Chair), Professor and Chief, Division of Occupational and Environmental Medicine, University of Pennsylvania Perelman School of Medicine
AMY BERNSTEIN, Policy Director and Contracting Officer (Retired), Medicaid and CHIP Payment and Access Commission
CHARLES H. BOMBARDIER, Professor, Department of Rehabilitation Medicine, University of Washington
JOSEPH A. BUCKWALTER, Professor and Steindler Chair, Department of Orthopedics and Rehabilitation, University of Iowa College of Medicine
ANDREA L. CHEVILLE, Professor, Physical Medicine and Rehabilitation, Mayo Clinic
LISA B. DIXON, Professor, Department of Psychiatry, Columbia University
ANNETTE FITZPATRICK, Research Professor, Department of Epidemiology, University of Washington School of Public Health and Community Medicine
JAIMIE L. GRADUS, Associate Professor, Epidemiology and Psychiatry, Boston University School of Public Health
STEPHEN S. GRUBBS, Vice President Clinical Affairs, American Society of Clinical Oncology ERIN E. KREBS, Associate Professor of Medicine, University of Minnesota
KNASHAWN H. MORALES, Associate Professor of Biostatistics, University of Pennsylvania Perelman School of Medicine PATRICIA M. OWENS, Consultant, Health and Disability Policy and Programs
NINA A. SAYER, Deputy Director, Center for Chronic Disease Outcomes Research, Minneapolis VA Healthcare System
TISAMARIE B. SHERRY, Associate Physician Policy Researcher, RAND Corporation
MICHAEL STUBBLEFIELD, Clinical Professor, Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School
Study Staff
CAROLYN FULCO, Scholar
MARIA ORIA, Senior Program Officer
BERNICE CHU, Program Officer
BLAKE REICHMUTH, Associate Program Officer
JOSEPH GOODMAN, Senior Program Assistant
ANNE MARIE HOUPPERT, Senior Research Librarian
SHARYL NASS, Senior Director, Board on Health Care Services
Consultant
NANETTE WENGER, Professor of Medicine, Department of Cardiology, Emory University School of Medicine
Reviewers
This Consensus Study Report was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine in making each published report as sound as possible and to ensure that it meets the institutional standards for quality, objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process.
We thank the following individuals for their review of this report:
Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations of this report nor did they see the final draft before its release. The review of this report was overseen by HAROLD C. SOX, Dartmouth Geisel School of Medicine, and BRADFORD H. GRAY, The Urban Institute. They were responsible for making certain that an independent examination of this report was carried out in accordance with the standards of the National Academies and that all review comments were carefully considered. Responsibility for the final content rests entirely with the authoring committee and the National Academies.
Contents
Social Security Disability Insurance Program
Social Security Supplemental Security Income Program
Social Security Administration’s Disability Determination Process
Social Security Administration’s Continuing Disability Review
Evolving Concepts of Disability
Approach to Pain and Pain Treatment
Comorbidities and Return to Work
Variation in Availability and Use of Effective Treatment
Epidemiology of Cancer in the United States
Head and Neck Squamous Cell Cancers
Advanced Epithelial Ovary Cancer
Disabling Impairments Related to the Selected Cancers and Cancer Treatments
Chemotherapy-Induced Peripheral Neuropathy
New and Developing Cancer Treatments
Variations in Treatment Response
Cross-Cutting Issues for Selected Mental Health Disorders
Epidemiology of Musculoskeletal Disorders in the United States
Cross-Cutting Issues for Musculoskeletal Disorders
Acronyms and Abbreviations
ACR | American College of Rheumatology |
ACS | American Cancer Society |
ADA | Americans with Disabilities Act |
ADHD/ADD | attention deficit hyperactivity disorder/attention deficit disorder |
AHRQ | Agency for Healthcare Research and Quality |
ALK | anaplastic lymphoma kinase |
APA | American Psychiatric Association |
ASCO | American Society of Clinical Oncology |
BDI-II | Beck Depression Inventory II |
BEP | brief eclectic psychotherapy |
BPI | Brief Pain Inventory |
BRCA1 | breast cancer type 1 susceptibility gene |
BRCA2 | breast cancer type 2 susceptibility gene |
CA-125 | carbohydrate antigen 125 |
CAL | compassionate allowance |
CANMAT | Canadian Network for Mood and Anxiety Treatments |
CBT | cognitive behavioral therapy |
CD | cognitive dysfunction |
CDC | Centers for Disease Control and Prevention |
CDK | cyclin-dependent kinase |
CDR | continuing disability review |
CDT | complex decongestive therapy |
CFR | Code of Federal Regulation |
CGI-I | Clinical Global Impression–Improvement |
CGI-S | Clinical Global Impression–Severity |
CIPN | chemotherapy-induced peripheral neuropathy |
CPT | cognitive processing therapy |
CRF | cancer-related fatigue |
CRP | C-reactive protein |
CT | computed tomography |
CTCAE | Common Terminology Criteria for Adverse Events |
CTLA-4 | cytotoxic T-lymphocyte-associated protein 4 |
DAS | Disability Assessment Schedule |
DCIS | ductal carcinoma in situ |
DMARD | disease-modifying antirheumatic drug |
DoD | U.S. Department of Defense |
DSM | Diagnostic and Statistical Manual of Mental Disorders |
DSM-IV | Diagnostic and Statistical Manual of Mental Disorders, 4th Edition |
DSM-IV-TR | Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision |
DSM-5 | Diagnostic and Statistical Manual of Mental Disorders, 5th Edition |
EBV | Epstein-Barr virus |
ECT | electroconvulsive therapy |
EGFR | epidermal growth factor receptor |
EMDR | eye movement desensitization and reprocessing therapy |
ER/PR/HER2 | tumor markers |
ERP | exposure and response prevention |
ESR | erythrocyte sedimentation rate |
EULAR | European League Against Rheumatism |
EX/RP | exposure and response prevention |
FACT | Functional Assessment of Cancer Therapy (questionnaire) |
FDA | U.S. Food and Drug Administration |
FDG | fluorodeoxyglucose |
FISH | fluorescence in situ hybridization |
FNA | fine needle aspiration |
GAD | generalized anxiety disorder |
GRAPPA | Group for Research and Assessment of Psoriasis and Psoriatic Arthritis |
HAM-D | Hamilton Depression Rating Scale |
HAQ | Health Assessment Questionnaire Disability Index |
HDRS | Hamilton Depression Rating Scale |
HER2 | human epidermal growth factor receptor 2 |
HIV | human immunodeficiency virus |
HPV | human papillomavirus |
IASP | International Association for the Study of Pain |
ICD | International Classification of Diseases |
ICF | International Classification of Functioning, Disability and Health |
ICI | immune checkpoint inhibitor |
IFNα | interferon alpha |
IFNβ | interferon beta |
IFNγ | interferon gamma |
IGH | immunoglobulin heavy chain |
IL-2 | interleukin-2 |
IMPACT | Initiative for Molecular Profiling and Advanced Cancer Therapy |
IOM | Institute of Medicine |
IPT | interpersonal therapy |
ISTSS | Society for Traumatic Stress Studies |
JAK | Janus kinase |
KC | keratinocyte carcinoma |
KPS | Karnofsky Performance Scale |
Li/DVP | lithium/divalproex |
LSAS | Liebowitz Social Anxiety Scale |
MADRS | Montgomery Asberg Depression Rating Scale |
MAOI | monoamine oxidase inhibitor |
MDD | major depressive disorder |
MIE | medical improvement expected |
MINE | medical improvement not expected |
MIP | medical improvement possible |
MRI | magnetic resonance imaging |
NCCN | National Comprehensive Cancer Network |
NCI | National Cancer Institute |
NCS-R | National Comorbidity Survey-Replication |
NET | narrative exposure therapy |
NHIS | National Health Interview Survey |
NICE | National Institute for Health and Care Excellence |
NIH | National Institutes of Health |
NMDA | N-methyl-D-aspartate receptor |
NPRM | notice of proposed rule making |
NSAID | non-steroidal anti-inflammatory drug |
NSCLC | non-small-cell lung cancer |
OA | osteoarthritis |
OCD | obsessive compulsive disorder |
ODT | orally dissolving tablet |
OIG | Office of Inspector General |
OMB | Office of Management and Budget |
OR | odds ratio |
PARP | poly (ADP-ribose) polymerase |
PCL | PTSD checklist |
PCT | present-centered therapy |
PD | panic disorder |
PD-1 | programmed cell death protein 1 |
PD-L1 | programmed death-ligand 1 |
PE | prolonged exposure |
PET | positron emission tomography |
PHQ | Patient Health Questionnaire |
PHQ-9 | Patient Health Questionnaire-9 |
PIK3CA | a protein coding gene |
PR | pulmonary rehabilitation |
PROMIS | Patient-Reported Outcomes Measurement Information System |
PsA | psoriatic arthritis |
PT | physical therapy |
PTSD | posttraumatic stress disorder |
QDD | Quick Disability Determination |
QoL | quality of life |
RA | rheumatoid arthritis |
RCT | randomized controlled trial |
RT | radiation therapy |
SAD | social anxiety disorder |
SCLC | small-cell lung cancer |
SEER | Surveillance, Epidemiology, and End Results |
SGA | substantial gainful activity |
SNRI | serotonin-norepinephrine reuptake inhibitor |
SRI | serotonin reuptake inhibitor |
SSA | Social Security Administration |
SSDI | Social Security Disability Insurance |
SSI | Social Security Insurance |
SSRI | selective serotonin reuptake inhibitor |
STAR*D | Sequenced Treatment Alternatives to Relieve Depression (study) |
SUD | substance use disorder |
TMS | transcranial magnetic stimulation |
TNF | tumor necrosis factor |
TNM | tumor, lymph nodes, metastasis |
TSH | thyroid-stimulating hormone |
VA | U.S. Department of Veterans Affairs |
VA/DoD | U.S. Department of Veterans Affairs and |
U.S. Department of Defense | |
VO2peak | volume of oxygen uptake during peak exercise |
WFSBP | World Federation of Societies of Biological Psychiatry |
WHO | World Health Organization |
XR | extended release |
YBOCS | Yale–Brown Obsessive Compulsive Scale |