Appendix C
Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed*by the Committee
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Abraham and Baird, 2012 | U.S. active-duty service members | X | Asthma; COPD; Pneumonia |
|||
Abraham et al., 2012 | U.S. service members | X | Respiratory Symptoms (ICD-9-CM 786); Asthma; COPD; Chronic Bronchitis |
|||
Abraham et al., 2014 | U.S. service members | X | AFHSC | Respiratory Symptoms (ICD-9-CM 786); Asthma; COPD |
||
Baird et al., 2012 | U.S./active-duty Army personnel | X | Respiratory Symptoms (ICD-9-CM 786); Sinusitis and Rhinitis; Asthma; COPD; Acute Bronchitis (ICD-9CM 460–466) |
|||
Banoei et al., 2019 | U.S. veterans | X | X | Interstitial Lung Disease (sarcoidosis) | ||
Barth et al., 2014 | U.S. veterans | X | NewGen | Sinusitis and Rhinitis; Asthma; Chronic Bronchitis |
X |
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Barth et al., 2016a | U.S. veterans | X | NewGen | Sinusitis and Rhinitis; Asthma; Chronic Bronchitis |
X | |
Barth et al., 2016b | U.S. veterans | X | Mortality | |||
Bollinger et al., 2015 | U.S. veterans | X | Mortality | |||
Butzko et al., 2019 | U.S. veterans | X | WRIISC | Pulmonary Function Testing | X | |
Davy et al., 2012 | Australian Defence Force active-duty personnel | X | Pulmonary Function Testing; COPD |
X | ||
DelVecchio et al., 2015 | U.S. active-duty Army personnel | X | Asthma | |||
Díaz Santana et al., 2017 | U.S. veterans | X | NewGen | Sleep Apnea | ||
Dion et al., 2013 | U.S. Army soldiers | X | Vocal Cord Dysfunction | X | ||
Eick et al., 2011 | U.S. active-duty service members | X | Pneumonia | |||
Falvo et al., 2016a | U.S. veterans | X | WRIISC | Pulmonary Function Testing | X | |
Falvo et al., 2016b | U.S. veterans | X | WRIISC | Pulmonary Function Testing | ||
Forbes et al., 2019 | U.S. active-duty service members | X | Interstitial Lung Disease (sarcoidosis) | |||
Gwini et al., 2016 | Australian veterans | X | Sleep Apnea; Asthma |
X | ||
Hines et al., 2013 | U.S. veterans | X | VA Depleted Uranium Surveillance Program | Respiratory Symptoms (frequent cough, coughing up phlegm, shortness of breath, wheezing); Sinusitis and Rhinitis; Pulmonary Function Testing; Asthma; Emphysema |
X | |
Holley et al., 2016 | U.S. service members, National Guard/reserves | X | Pulmonary Function Testing | X |
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Hooper et al., 2008 | U.S. active-duty veterans of Gulf War | X | Sinusitis and Rhinitis; Interstitial Lung Disease (sarcoidosis); Pneumonia |
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Jani et al., 2017a | U.S. service members | X | AH&OBP Registry/WRIISC | Respiratory Symptoms (dyspnea, decreased exercise tolerance) | X | |
Jani et al., 2017b | U.S. service members | X | AH&OBP Registry | Constrictive Bronchiolitis | X | |
Khalil et al., 2018 | U.S. veterans | X | Gulf War Era Cohort and Biorepository | Respiratory Symptoms (difficulty breathing, shortness of breath, frequent coughing without a cold, wheezing in chest); Sleep Apnea; COPD; Emphysema; Constrictive Bronchiolitis; TB; Cancers |
||
King et al., 2011 | U.S. active-duty Army soldiers | X | Constrictive Bronchiolitis | X | ||
Krefft et al., 2017 | U.S. veterans | X | Respiratory Symptoms (cough, chest tightness, wheezing, shortness of breath, decreased exercise tolerance); Pulmonary Function Testing; Emphysema; Constrictive Bronchiolitis; Interstitial Lung Disease (hypersensitivity pneumonitis) |
X | ||
Krefft et al., 2020 | U.S. service members | X | Pulmonary Function Testing; Emphysema; Constrictive Bronchiolitis; Interstitial Lung Disease (hypersensitivity pneumonitis) |
X | ||
Lindheimer et al., 2019 | U.S. veterans | X | WRIISC | Pulmonary Function Testing | X |
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Liu et al., 2016 | U.S. service members | X | AH&OBP Registry | Asthma; COPD; Emphysema; Chronic Bronchitis |
X | |
Madar et al., 2017 | U.S. military personnel | X | X | Pulmonary Function Testing; Constrictive Bronchiolitis; Interstitial Lung Disease (sarcoidosis, acute eosinophilic pneumonia, pulmonary alveolar proteinosis, idiopathic interstitial pneumonia) |
X | |
Matthews et al., 2014 | U.S. active-duty service members | X | Pulmonary Function Testing; COPD; Emphysema |
X | ||
Maule et al., 2018 | Veterans (Australia, Denmark, United Kingdom, United States) | X | Respiratory Symptoms (coughing, wheezing, shortness of breath); Sinusitis and Rhinitis; Asthma |
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Morris et al., 2014 | U.S. active-duty service members | X | STAMPEDE | Respiratory Symptoms (dyspnea, cough, wheeze, sputum production); Pulmonary Function Testing |
||
Morris et al., 2019 | U.S. active-duty Army personnel | X | STAMPEDE | Respiratory Symptoms (dyspnea, cough, wheezing, sputum production, exercise intolerance); Pulmonary Function Testing |
X | |
Morris et al., 2020 | U.S. service members | X | STAMPEDE | Respiratory Symptoms (exertional dyspnea, cough, wheeze, sputum production, decreased exercise tolerance); Pulmonary Function Testing; Constrictive Bronchiolitis |
X | |
OIF SAPEG, 2003 | U.S. active duty military personnel, Reserve/National Guard | X | Interstitial Lung Disease (acute eosinophilic pneumonia) | X |
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Peacock et al., 1997 | U.S. veterans | X | Comprehensive Clinical Evaluation Program | Sleep Apnea | ||
Pugh et al., 2016 | U.S. veterans | X | Asthma; COPD; Interstitial Lung Disease |
X | ||
Rivera et al., 2018 | U.S. service members, Reserve/National Guard | X | Millennium Cohort Study | Asthma | X | |
Rohrbeck et al., 2016 | U.S. active-duty service members | X | Respiratory Symptoms (ICD-9-CM 786); Sleep Apnea; Cancers |
|||
Roop et al., 2007 | U.S. active-duty Army soldiers | X | Asthma | X | ||
Saers et al., 2017 | Swedish military personnel | X | Respiratory Symptoms (wheeze, wheeze with breathlessness, wheeze without a cold, nocturnal chest tightness, nocturnal breathlessness, nocturnal cough); Chronic Bronchitis |
X | ||
Sharkey et al., 2015 | U.S. service members | X | AFHSC | Respiratory Symptoms (ICD-9-CM 786); Asthma; COPD; Acute Bronchitis |
X | |
Sharkey et al., 2016 | U.S. service members | X | AFHSC | Respiratory Symptoms (ICD-9-CM 786); Asthma; COPD |
X | |
Shorr et al., 2004 | U.S. active-duty service members | X | Interstitial Lung Disease (acute eosinophilic pneumonia) | X | ||
Sine et al., 2018 | U.S. active-duty service members | X | Interstitial Lung Disease (acute eosinophilic pneumonia) | X | ||
Smith et al., 2008 | U.S. active-duty service members | X | Millennium Cohort Study | Sinusitis and Rhinitis; Sleep Apnea; Asthma; Emphysema; Chronic Bronchitis |
Referencea | Population | 1990–1991 Gulf War | Post-9/11 | Study Populationb | Outcomes Assessedc | Smoking Status Collectedd |
---|---|---|---|---|---|---|
Smith et al., 2009 | U.S. service members, Reserve/National Guard | X | Millennium Cohort Study | Respiratory Symptoms (persistent or recurring cough or shortness of breath); Asthma; Emphysema; Chronic Bronchitis |
X | |
Smith et al., 2012 | U.S. service members | X | Millennium Cohort Study | Respiratory Symptoms (persistent or recurring cough or shortness of breath); Asthma; Emphysema; Chronic Bronchitis |
X | |
Soltis et al., 2009 | U.S. active-duty service members | X | Acute Bronchitis | |||
Szema et al., 2010 | U.S. veterans | X | Asthma | |||
Szema et al., 2011 | U.S. veterans | X | Pulmonary Function Testing | X | ||
Taylor and Ross, 2019 | British active-duty service personnel | X | Respiratory Symptoms (shortness of breath, wheeze, cough); Sinusitis and Rhinitis |
|||
Weinstein et al., 2016 | U.S. active-duty service members | X | Pulmonary Function Testing | |||
Woods et al., 2018 | U.S. active-duty Army personnel | Asthma | X | |||
Zundel et al., 2019 | U.S. veterans | X | Asthma; Chronic Bronchitis |
X |
* “Newly Reviewed” studies are those that have not been addressed in previous National Academies reports.
a Full citations may be found in the References section of Chapter 4.
b Study populations of cohorts that were specified in the Statement of Task are noted.
c Only those outcomes that are addressed in the report are listed. A study may have also addressed other outcomes.
d An “X” indicates that information on smoking was collected, but this does not necessarily mean that it was collected consistently or used in analyses.
NOTE: AFHSC, Armed Forces Health Surveillance Center; AH&OBP, Airborne Hazards and Open Burn Pit; COPD, chronic obstructive pulmonary disease; ICD-9-CM, International Classification of Diseases, 9th edition, Clinical Modification; NewGen, National Health Study for a New Generation of U.S. Veterans; STAMPEDE, Study of Active Duty Military for Pulmonary Disease Related to Environmental Deployment Exposures; TB, tuberculosis; WRIISC, VA War Related Illness and Injury Study Center.