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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

Advancing Progress in
the Development and
Implementation of
Effective, High-Quality
Cancer Screening

PROCEEDINGS OF A WORKSHOP

Erin Balogh, Sarah Domnitz, Margie Patlak, and Sharyl J. Nass,
Rapporteurs

National Cancer Policy Forum

Board on Health Care Services

Health and Medicine Division

images

THE NATIONAL ACADEMIES PRESS
Washington, DC
www.nap.edu

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001

This activity was supported by Contract No. 200-2011-38807 (Task Order No. 75D30119F00080) and Contract No. HHSN263201800029I (Task Order No. HHSN26300008) with the Centers for Disease Control and Prevention and the National Cancer Institute/National Institutes of Health, respectively, and by the American Association for Cancer Research, American Cancer Society, American College of Radiology, American Society of Clinical Oncology, Association of American Cancer Institutes, Association of Community Cancer Centers, Bristol-Myers Squibb, Cancer Support Community, CEO Roundtable on Cancer, Flatiron Health, Merck, National Comprehensive Cancer Network, National Patient Advocate Foundation, Novartis Oncology, Oncology Nursing Society, Pfizer Inc., Sanofi, and Society for Immunotherapy of Cancer. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.

International Standard Book Number-13: 978-0-309-13659-4
International Standard Book Number-10: 0-309-13659-8
Digital Object Identifier: https://doi.org/10.17226/26019

Additional copies of this publication are available from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

Copyright 2021 by the National Academy of Sciences. All rights reserved.

Printed in the United States of America

Suggested citation: National Academies of Sciences, Engineering, and Medicine. 2021. Advancing progress in the development and implementation of effective, high-quality cancer screening: Proceedings of a workshop. Washington, DC: The National Academies Press. https://doi.org/10.17226/26019.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

Image

The National Academy of Sciences was established in 1863 by an Act of Congress, signed by President Lincoln, as a private, nongovernmental institution to advise the nation on issues related to science and technology. Members are elected by their peers for outstanding contributions to research. Dr. Marcia McNutt is president.

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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

WORKSHOP PLANNING COMMITTEE1

NICOLE F. DOWLING (Co-Chair), Associate Director for Science, Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention

STANTON L. GERSON (Co-Chair), Interim Dean and Senior Vice President, Medical Affairs, School of Medicine; Director, Case Comprehensive Cancer Center; Professor of Hematological Oncology; and Director, National Center for Regenerative Medicine, Case Western Reserve University

GARNET L. ANDERSON, Senior Vice President and Director, Public Health Sciences Division, Fred Hutchinson Cancer Research Center; Principal Investigator, Clinical Coordinating Center, Women’s Health Initiative; and Affiliate Professor, Department of Biostatistics, University of Washington

KENNETH ANDERSON, Kraft Family Professor of Medicine; American Cancer Society Research Professor; and Clinical Research Director, Jerome Lipper Multiple Myeloma Center and LeBow Institute for Myeloma Therapeutics, Harvard Medical School and Dana-Farber Cancer Institute

EDWARD J. BENZ, JR., President and Chief Executive Officer, Emeritus, Dana-Farber Cancer Institute; and Richard and Susan Smith Distinguished Professor of Medicine, Genetics and Pediatrics, Harvard Medical School

OTIS W. BRAWLEY, Bloomberg Distinguished Professor of Epidemiology and Oncology, Bloomberg School of Public Health, Sidney Kimmel Comprehensive Cancer Center, and School of Medicine, Johns Hopkins University

SUSAN CURRY, Dean Emerita, College of Public Health; and Distinguished Professor, Health Management and Policy, The University of Iowa

NANCY E. DAVIDSON, President and Executive Director, Seattle Cancer Care Alliance; Raisebeck Endowed Chair for Collaborative Research, Senior Vice President, Director, and Professor, Clinical Research Division, Fred Hutchinson Cancer Research Center; and Head, Department of Medicine, Division of Medical Oncology, University of Washington

___________________

1 The National Academies of Sciences, Engineering, and Medicine’s planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers. The responsibility for the published Proceedings of a Workshop rests with the workshop rapporteurs and the institution.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

CONSTANTINE GATSONIS, Henry Ledyard Goddard University Professor of Biostatistics; Founding Director, Center for Statistical Sciences; and Founding Chair, Department of Biostatistics, Brown University

LORI HOFFMAN HŌGG, Veterans Health Administration National Program Manager for Prevention Policy, National Center for Health Promotion and Disease Prevention; and National Oncology Clinical Advisor, Office of Nursing Services, Department of Veterans Affairs

HEDVIG HRICAK, Chair, Department of Radiology, Memorial Sloan Kettering Cancer Center

ALEX KRIST, Professor, Family Medicine & Population Health; Co-Director, Virginia Ambulatory Care Outcomes Research Network; and Director, Community Engaged Research, Center for Clinical and Translational Research, Virginia Commonwealth University; and Chair, United States Preventive Services Task Force

MICHELLE M. LE BEAU, Arthur and Marian Edelstein Professor of Medicine, Section of Hematology/Oncology; Director, Cancer Cytogenetics Laboratory; and Director, Comprehensive Cancer Center, University of Chicago

LISA RICHARDSON, Director, Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention

SUDHIR SRIVASTAVA, Chief, Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute

ROBERT A. WINN, Director, Massey Cancer Center, and Professor of Internal Medicine, School of Medicine, Virginia Commonwealth University

Project Staff

ERIN BALOGH, Co-Director, National Cancer Policy Forum

LORI BENJAMIN BRENIG, Research Associate

RACHEL AUSTIN, Senior Program Assistant (from November 2020)

KATHERINE HAWTHORNE, Senior Program Assistant (until September 2020)

EMILY ZEVON, Program Officer

ANNALEE GONZALES, Administrative Assistant

MICAH WINOGRAD, Senior Finance Business Partner

SHARYL NASS, Co-Director, National Cancer Policy Forum, and Senior Director, Board on Health Care Services

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

NATIONAL CANCER POLICY FORUM1

EDWARD J. BENZ, JR. (Chair), President and Chief Executive Officer, Emeritus, Dana-Farber Cancer Institute; and Richard and Susan Smith Distinguished Professor of Medicine, Genetics and Pediatrics, Harvard Medical School

PETER C. ADAMSON, Global Head, Oncology Development & Pediatric Innovation, Sanofi

GARNET L. ANDERSON, Senior Vice President and Director, Public Health Sciences Division, Fred Hutchinson Cancer Research Center; Principal Investigator, Clinical Coordinating Center, Women’s Health Initiative; and Affiliate Professor, Department of Biostatistics, University of Washington

KAREN BASEN-ENGQUIST, Annie Laurie Howard Research Distinguished Professor; Professor of Behavioral Science; and Director, Center for Energy Balance in Cancer Prevention and Survivorship, University of Texas MD Anderson Cancer Center

SMITA BHATIA, Professor and Vice Chair of Outcomes for Pediatrics; Gay and Bew White Endowed Chair in Pediatric Oncology; Director, Institute for Cancer Outcomes and Survivorship; and Associate Director for Outcomes Research, Comprehensive Cancer Center, The University of Alabama at Birmingham

LINDA BOHANNON, President, Cancer Support Community

CHRIS BOSHOFF, Chief Development Officer, Oncology, Pfizer Inc.

CATHY J. BRADLEY, Grohne Chair for Cancer Prevention and Control Research; Professor and Associate Dean for Research, Colorado School of Public Health; and Deputy Director, University of Colorado Cancer Center

OTIS W. BRAWLEY, Bloomberg Distinguished Professor of Epidemiology and Oncology, Bloomberg School of Public Health, Sidney Kimmel Comprehensive Cancer Center, and School of Medicine, Johns Hopkins University

CYNTHIA BROGDON, Head, U.S. Oncology Portfolio Strategy, Bristol Myers Squibb

WILLIAM G. CANCE, Chief Medical and Scientific Officer, American Cancer Society

___________________

1 The National Academies of Sciences, Engineering, and Medicine’s forums and roundtables do not issue, review, or approve individual documents. The responsibility for the published Proceedings of a Workshop rests with the workshop rapporteurs and the institution.

Page viii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

ROBERT W. CARLSON, Chief Executive Officer, National Comprehensive Cancer Network

CHRISTINA CHAPMAN, Assistant Professor of Radiation Oncology, University of Michigan

K. ANDREW CRIGHTON, Chief Executive Officer, CEO Roundtable on Cancer

GWEN DARIEN, Executive Vice President, Patient Advocacy and Engagement, National Patient Advocate Foundation

NANCY E. DAVIDSON, President and Executive Director, Seattle Cancer Care Alliance; Raisebeck Endowed Chair for Collaborative Research, Senior Vice President, Director, and Professor, Clinical Research Division, Fred Hutchinson Cancer Research Center; and Head, Department of Medicine, Division of Medical Oncology, University of Washington

GEORGE D. DEMETRI, Professor of Medicine and Director, Ludwig Center, Harvard Medical School; Senior Vice President for Experimental Therapeutics; Director, Center for Sarcoma and Bone Oncology; Quick Family Chair for Medical Oncology, Dana-Farber Cancer Institute; and Associate Director for Clinical Sciences, Dana-Farber/Harvard Cancer Center

JAMES H. DOROSHOW, Director, Division of Cancer Treatment and Diagnosis; Deputy Director for Clinical and Translational Research; and Head, Oxidative Signaling and Molecular Therapeutics Group, National Cancer Institute

NICOLE F. DOWLING, Associate Director for Science, Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention

SCOT W. EBBINGHAUS, Vice President and Therapeutic Area Head, Oncology Clinical Research, Merck Research Laboratories

KOJO S. J. ELENITOBA-JOHNSON, Professor, Perelman School of Medicine; and Director, Center for Personalized Diagnostics and Division of Precision and Computational Diagnostics, University of Pennsylvania

STANTON L. GERSON, Interim Dean and Senior Vice President, Medical Affairs, School of Medicine; Director, Case Comprehensive Cancer Center; Professor of Hematological Oncology; and Director, National Center for Regenerative Medicine, Case Western Reserve University

HEDVIG HRICAK, Chair, Department of Radiology, Memorial Sloan Kettering Cancer Center

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

CHANITA HUGHES-HALBERT, Associate Dean for Assessment, Evaluation, and Quality Improvement, College of Medicine; Professor, Department of Psychiatry and Behavioral Sciences; Distinguished AT&T Endowed Chair for Cancer Equity, Hollings Cancer Center, Medical University of South Carolina

MIMI HUIZINGA, Vice President and Head, U.S. Oncology Medical, Novartis Oncology

ROY A. JENSEN, Professor of Pathology and Laboratory Medicine, Anatomy and Cell Biology, and Cancer; Director, The University of Kansas Cancer Center; William R. Jewell, M.D., Distinguished Masonic Professor; and Director, Kansas Masonic Cancer Research Institute, University of Kansas

RANDY A. JONES, Professor of Nursing, University of Virginia School of Nursing; and Assistant Director for Community Outreach Engagement, University of Virginia Emily Couric Cancer Center

BETH Y. KARLAN, Vice Chair, Women’s Health Research; Professor, Department of Obstetrics and Gynecology, David Geffen School of Medicine; and Director, Cancer Population Genetics, Jonsson Comprehensive Cancer Center, University of California, Los Angeles

LISA KENNEDY SHELDON, Clinical and Scientific Affairs Liaison, Oncology Nursing Society; and Oncology Nurse Practitioner, St. Joseph Hospital

SAMIR N. KHLEIF, Director, Jeannie and Tony Loop Immuno-Oncology Lab; Biomedical Scholar and Professor of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center; and Member, Society for Immunotherapy of Cancer

KAREN E. KNUDSEN, President, Association of American Cancer Institutes; Executive Vice President, Oncology Services; Enterprise Director, Sidney Kimmel Cancer Center, Jefferson Health

MIA LEVY, Sheba Foundation Director, Rush University Cancer Center; Associate Professor of Medicine, Division of Hematology and Oncology; and System Vice President, Cancer Services, Rush System for Health

SCOTT M. LIPPMAN, Director, Moores Cancer Center; Professor of Medicine, Senior Associate Dean, and Associate Vice Chancellor for Cancer Research and Care; Chugai Pharmaceutical Chair in Cancer, University of California, San Diego

NEAL MEROPOL, Vice President and Head of Medical and Scientific Affairs, Flatiron Health; and Adjunct Professor, Case Comprehensive Cancer Center

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

LARISSA NEKHLYUDOV, Professor of Medicine, Harvard Medical School; Internist, Brigham & Women’s Primary Care Associates at Longwood; Clinical Director, Internal Medicine for Cancer Survivors, Dana-Farber Cancer Institute

RANDALL A. OYER, Medical Director, Oncology, Ann B. Barshinger Cancer Institute; and Medical Director, Cancer Risk Evaluation Program, Penn Medicine Lancaster General Health

CLEO A. SAMUEL-RYALS, Associate Professor, Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill

RICHARD L. SCHILSKY, Senior Vice President, Executive Vice President, and Chief Medical Officer, American Society of Clinical Oncology

JULIE SCHNEIDER, Associate Director, Research Strategy and Partnership, Oncology Center of Excellence, Food and Drug Administration

LAWRENCE N. SHULMAN, Professor of Medicine and Deputy Director for Clinical Services and Director, Center for Global Cancer Medicine, Abramson Cancer Center, University of Pennsylvania

LARA STRAWBRIDGE, Director, Division of Ambulatory Payment Models, Patient Care Models Group, Center for Medicare & Medicaid Innovation, Centers for Medicare & Medicaid Services

GEORGE J. WEINER, C. E. Block Chair of Cancer Research; Professor of Internal Medicine; Professor of Pharmaceutical Science Experimental Therapeutics; and Director, Holden Comprehensive Cancer Center, The University of Iowa

ROBERT A. WINN, Director, Massey Cancer Center, and Professor of Internal Medicine, School of Medicine, Virginia Commonwealth University

Forum Staff

ERIN BALOGH, Co-Director, National Cancer Policy Forum

LORI BENJAMIN BRENIG, Research Associate

RACHEL AUSTIN, Senior Program Assistant

ANNALEE GONZALES, Administrative Assistant

MICAH WINOGRAD, Senior Finance Business Partner

SHARYL NASS, Co-Director, National Cancer Policy Forum, and Senior Director, Board on Health Care Services

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

Reviewers

This Proceedings of a Workshop was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine in making each published proceedings as sound as possible and to ensure that it meets the institutional standards for quality, objectivity, evidence, and responsiveness to the charge. The review comments and draft manuscript remain confidential to protect the integrity of the process.

We thank the following individuals for their review of this proceedings:

Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the content of the proceedings nor did they see the final draft before its release. The review of this proceedings was overseen by DANIEL R. MASYS, University of Washington. He was responsible for making certain that an independent examination of this proceedings was carried out in accordance with standards of the National Academies and that all review comments were carefully considered. Responsibility for the final content rests entirely with the rapporteurs and the National Academies.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

Acknowledgments

Support from the many annual sponsors of the National Academies of Sciences, Engineering, and Medicine’s National Cancer Policy Forum is crucial to the work of the forum. Federal sponsors include the Centers for Disease Control and Prevention and the National Cancer Institute/National Institutes of Health. Nonfederal sponsors include the American Association for Cancer Research, American Cancer Society, American College of Radiology, American Society of Clinical Oncology, Association of American Cancer Institutes, Association of Community Cancer Centers, Bristol-Myers Squibb, Cancer Support Community, CEO Roundtable on Cancer, Flatiron Health, Merck, National Comprehensive Cancer Network, National Patient Advocate Foundation, Novartis Oncology, Oncology Nursing Society, Pfizer Inc., Sanofi, and Society for Immunotherapy of Cancer.

The forum wishes to express its gratitude to the expert speakers whose presentations helped further the dialogue on opportunities to improve the evidence base for and delivery of high-quality cancer screening. The forum also wishes to thank the members of the planning committee for their work in developing an excellent workshop agenda.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×

Acronyms and Abbreviations

AHRQ Agency for Healthcare Research and Quality
AI artificial intelligence
CDC Centers for Disease Control and Prevention
CLIA Clinical Laboratory Improvement Amendments
CMS Centers for Medicare & Medicaid Services
CRCCP Colorectal Cancer Control Program
CT computed tomography
EDRN Early Detection Research Network
ERSPC European Randomized Study of Screening for Prostate Cancer
FDA Food and Drug Administration
FQHC federally qualified health center
HMO health maintenance organization
HPV human papillomavirus
LEEP loop electrosurgical excision procedure
MPS MyProstateScore
MRI magnetic resonance imaging
MyPeBS My Personal Breast Screening
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
×
NCCN National Comprehensive Cancer Network
NCI National Cancer Institute
NICE National Institute for Health and Care Excellence
NIH National Institutes of Health
PET positron emission tomography
PLCO Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
PSA prostate-specific antigen
RCT randomized controlled trial
ROC risk of ovarian cancer
SNP single nucleotide polymorphism
TMIST Tomosynthesis Mammographic Imaging Screening Trial
TVS transvaginal ultrasound
UKCTOCS UK Collaborative Trial of Ovarian Cancer Screening
USPSTF United States Preventive Services Task Force
VHA Veterans Health Administration
WHO World Health Organization
WISDOM Women Informed to Screen Depending on Measures of Risk
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2021. Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26019.
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New technologies and improved understanding of the genesis and progression of various cancers have added to the enthusiasm for potential new strategies to improve screening and early detection of cancer. Research is also under way to evaluate refinements in current screening approaches, including determining optimal screening intervals, the ages at which screening should begin and end, as well as more specific estimates of the potential risks and benefits of screening for certain populations, such as racial and ethnic minority populations and people who have elevated risk for specific cancers. However, there remain significant challenges to developing, validating, and effectively implementing new cancer screening approaches. Guidelines for screening issued by different organizations vary considerably with no clear way of deciding which guidelines are most trustworthy. There is also a need to improve access to high-quality cancer screening and follow-up care, particularly in low-resource communities and among populations who are underserved or have numerous barriers to receiving care.

To examine the challenges and opportunities related to improving current approaches to cancer screening, as well as the evidence base for novel cancer screening methods, the National Cancer Policy Forum held a workshop, Advancing Progress in the Development and Implementation of Effective, High-Quality Cancer Screening, on March 2-3, 2020, in Washington, DC. This workshop convened a broad range of experts, including clinicians, researchers, statisticians, and patient advocates, as well as representatives of health care organizations, academic medical centers, insurers, and federal agencies. This publication summarizes the presentations and discussions of the workshop and highlights suggestions from individual participants regarding how to improve cancer screening.

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