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Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop (2022)

Chapter: Appendix B: Speaker and Poster Presenter Biographies

« Previous: Appendix A: Workshop Agenda
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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Appendix B

Speaker and Poster Presenter Biographies

SESSION I. TRIANGULATION: BACKGROUND, METHODOLOGIES, AND APPLICATIONS

Deborah A. Lawlor is a Professor of Epidemiology and the Deputy Director of the UK Medical Research Council Integrative Epidemiology Unit (IEU) at the University of Bristol. She has a background in clinical and public health medicine, and her research is concerned with the causes and consequences of adverse reproductive, perinatal, and cardiometabolic health. With colleagues in the IEU and external collaborators, she has been proposing criteria and developing methods for triangulation of evidence to improve causal inference in epidemiology.

Neil Pearce is a Professor of Epidemiology and Biostatistics at the London School of Hygiene & Tropical Medicine (LSHTM). He joined LSHTM at the beginning of 2011, after working in New Zealand for 30 years. He originally trained in biostatistics, before earning a PhD in epidemiological methods in 1985. He has been engaged in a wide range of public health research activities. His current research interests focus on epidemiological and biostatistical methods and their application to studies of noncommunicable diseases, including occupational and environmental health, asthma, kidney disease, and neurological disease. He has a particular interest in global epidemiological studies. Pearce is a fellow of the Royal Society of New Zealand and the Academy of Medical Sciences and the Past-President of the International Epidemiological Association.

Kyle Steenland is a Professor in the Emory University Rollins School of Public Health. He is an environmental occupational epidemiologist who first worked at the Centers for Disease Control and Prevention’s National Institute for Occupational Safety and Health from 1982 to 2002 before joining the Rollins School of Public Health. His projects at Emory University are diverse and include PFOA, occupational lead, and household air pollution. Steenland and colleagues conducted a review of risk of bias tools, which was published in Environmental Health Perspectives in 2020. He is part of a group that is developing a new risk of bias tool called ROBINS-E.

Eric J. Tchetgen Tchetgen is the Luddy Family President’s Distinguished Professor and a Professor of Statistics and Data Science at the Wharton School of the University of Pennsylvania. Tchetgen Tchetgen’s research focuses on causal inference, missing data, and semiparametric theory with applications in HIV and other infectious disease, genetic, social, and environmental Epidemiology.

SESSION II. HEALTH AUTHORITY PERSPECTIVES ON SYNTHESIS OF EPIDEMIOLOGIC EVIDENCE

Joseph Haney has served as a regulatory toxicologist and risk assessor at the Texas Commission on Environmental Quality for more than 24 years. He has interest in multiple areas, including the hazard identification, dose-response assessment, mode of action, inhalation dosimetry, toxicokinetic/toxicodynamic differences, and low-dose extrapolation issues. Haney has conducted dose-response analyses for numerous chemicals (e.g., benzene, methylene chloride, formaldehyde, 1,4-dichlorobenzene, trimethylbenzenes, hexavalent chromium, cadmium, cobalt, nickel) and derived associated toxicity factors (e.g., unit risk factors, reference concentrations and doses). He has published several chemical dose-response assessments and related papers. Regarding exposure to drinking water contaminants and associated health hazard, Haney has also published a paper on historical drinking water

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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contamination at Camp Lejeune, North Carolina. Haney was born on Camp Lejeune and raised in Houston, Texas, where he received his BS in biology (summa cum laude) from the University of Houston and his MS in environmental science with emphasis in toxicology from the University of Texas School of Public Health. He is a member of the Society of Toxicology and its Risk Assessment Specialty Section, as well as the Society for Risk Analysis.

Ruth Lunn has been the head of the Report on Carcinogens (RoC) Group since 2008. The RoC is a U.S. congressionally mandated, science-based, public health document that identifies and discusses cancer hazards. During her more than 20-year tenure at the National Institute of Environmental Health Sciences (NIEHS), Lunn has led or contributed to numerous publications, including more than 50 cancer hazard evaluations; developed systematic review methods (RoC handbook) and tools; and modified the RoC review process. She has served on national or international groups/panels that evaluated programs, advised priorities, developed systematic review methods, conducted cancer hazard evaluations (such as the International Agency for Research on Cancer), and organized webinars or meeting symposiums. Lunn’s research interests include advancing cancer hazard evaluation approaches to meet contemporary problems and increasing the public health impact of the RoC. She is also interested in raising the visibility of environmental health disparities and environmental justice issues at NIEHS. Lunn has a DrPH in environmental health sciences from Columbia University and an MS from Drexel University.

Rebecca Nachman is an epidemiologist in the Center for Public Health and Environmental Assessment at the U.S. Environmental Protection Agency (EPA), where she reviews evidence regarding the human health effects of chemical exposures for EPA’s Integrated Risk Information System Program. She received her PhD from the Johns Hopkins Bloomberg School of Public Health, where she investigated the early life toxicokinetics of bisphenol A. Prior to joining EPA, she conducted research as a postdoctoral fellow on the effects of early life exposure to air pollution in the Boston Birth Cohort. More recently, she has published on adapting systematic review methods to evaluate environmental epidemiology and exposure sciences literature.

Jonathan Samet (NAM), a pulmonary physician and epidemiologist, is the Dean of the Colorado School of Public Health. Previously, he has held leadership positions at the University of New Mexico School of Medicine, the Johns Hopkins Bloomberg School of Public Health, and the University of Southern California Keck School of Medicine. His research has focused on the health risks of inhaled pollutants in outdoor air and also indoor pollutants including secondhand smoke and radon. He has also investigated the occurrence and causes of cancer and respiratory diseases, emphasizing the risks of active and passive smoking. He has served on and chaired numerous committees of the National Research Council and the National Academies of Sciences, Engineering, and Medicine, including chairing the Board on Environmental Studies and Toxicology. For several decades, he has been involved in global health, focusing on tobacco control, air pollution, and chronic disease prevention. He has been the chair of the U.S. Environmental Protection Agency’s Clean Air Scientific Advisory Committee and the U.S. Food and Drug Administration’s Tobacco Products Scientific Advisory Committee. Samet has served as the editor and author for reports of the Surgeon General on smoking and health since 1984, receiving the Surgeon General’s Medallion in 1990 and 2006 for these contributions. Samet received the 2004 Prince Mahidol Award for Global Health awarded by the King of Thailand, the Edward Livingston Trudeau Medal from the American Thoracic Society/American Lung Association, the Luther Terry Award for Distinguished Career from the American Cancer Society, and the Fries Prize for Health. He received the Alumni Award of Merit from the Harvard T.H. Chan School of Public Health in 2001 and was named Distinguished Alumnus of the Year by the University of Rochester School of Medicine and Dentistry in 2006. He was elected to the National Academy of Medicine in 1997 and received the David Rall Medal in 2015.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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Mary Schubauer-Berigan is the Deputy Branch Head of the Evidence Synthesis and Classification Branch of the International Agency for Research on Cancer (IARC), where she heads the Monographs Program. She joined IARC in 2018 as the Senior Epidemiologist for the Monographs. She currently manages a scientific and technical staff of 16 in leading evaluations of the epidemiologic, experimental, and mechanistic evidence bases to identify the preventable causes of human cancer. At IARC, Schubauer-Berigan has co-led the update of the guiding principles (Preamble) for the Monographs, bringing increased transparency and scientific advances to this program, which is essential for cancer prevention worldwide. She has been the Responsible Officer for monographs on nightshift work, opium consumption, and occupational exposure as a firefighter. Before joining IARC, she worked for nearly 20 years as an epidemiologist at the National Institute for Occupational Safety and Health. There, she led multidisciplinary teams conducting epidemiology studies of the health effects of occupational exposures to beryllium, carbon nanotubes, nuclear work, radon, cosmic radiation, and circadian disruption. Schubauer-Berigan has co-authored more than 125 publications on the above topics. She received a PhD in epidemiology from the Medical University of South Carolina and an MS in biology from the University of Minnesota.

SESSION III. POSTER PRESENTATIONS

Thomas Bateson is a Senior Epidemiologist with the U.S. Environmental Protection Agency’s (EPA’s) Office of Research and Development in the Center for Public Health and Environmental Assessment in Washington, DC. He earned an MPH in epidemiology and biostatistics from the University of California, Berkeley, and a DSc in epidemiologic methods from the Harvard T.H. Chan School of Public Health. Before joining EPA in 2006, Bateson studied the causes of birth defects, children’s health and development, the health of military personnel, and the effect of air pollution on the elderly using the case-crossover study design. At EPA, he works together with statisticians and toxicologists from multiple disciplines to identify hazards and to quantify the associated risks. Bateson has contributed to the EPA Integrated Risk Information System assessments of environmental agents such as asbestos, formaldehyde, hexavalent chromium, manganese, and per- and polyfluoroalkyl substances. He has also contributed to the Office of Chemical Safety and Pollution Protection’s Toxic Substances Control Act risk evaluations of chrysotile asbestos and carbon tetrachloride, as well as the Office of Water’s evaluations of PFOS and PFOA.

Mireya Diaz received a doctorate degree in biostatistics from Case Western Reserve University. She is a Professor and the Chief of Epidemiology and Biostatistics at the Homer Stryker M.D. School of Medicine at Western Michigan University. She has 20 years of statistical consulting and research experience. Her research interests include the development, application, and evaluation of statistical methods for correlated data and effectiveness research with large observational data. Among her contributions to health technology assessment and these methods are evaluations of (1) the comparative effectiveness of robotic prostatectomy from the Vattikuti Urology Institute, one of the largest and pioneering centers of the technique; (2) through meta-analyses the evidence used in the guidelines developed by the American Urological Association related to the management of vesicoureteral reflux in children, cryptorchidism, and follow-up of the renal mass; (3) the evidence about infiltrates incidence with extended wear lenses, later used by Vistakon for U.S. Food and Drug Administration approval of its corresponding product; (4) the bivariate random effects model for diagnostic accuracy; and (5) the methodological state of the art regarding indirect treatment comparisons and network meta-analysis through the pertinent International Society for Pharmacoeconomics and Outcomes Research Task Force.

Jamie Donatuto is a Community Environmental Health Analyst for the Swinomish Indian Tribal Community, located in the Pacific Northwest of the United States. A Swinomish staff member for the past 22 years, Donatuto specializes in working with Indigenous communities across North America in the development and implementation of projects that uphold the community’s values and address the

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

community’s priorities, as well as distilling and communicating results for multiple audiences using mixed methods and structured decision-making analyses. In her research, she uses social science methods to improve natural resource management decision-making, such as modifying human health risk assessments to reflect Indigenous values; analyzing toxics in local traditional foods and subsequent Indigenous health impacts; evaluating climate related impacts to Indigenous health and well-being; and developing adaptive management strategies founded on Indigenous ways of knowing. Donatuto completed her doctoral studies at the University of British Columbia, Vancouver, Canada, in the interdisciplinary program with a focus on Indigenous community health and environmental studies.

Pengfei Guo is a PhD candidate in Department of Environmental Health Sciences of the Yale School of Public Health, working with Dr. Zeyan Liew. Guo’s research interests include environmental exposure and maternal and child health, chemical mixture, and causal inference. Guo is also a Chinese Podcaster for the American Journal of Public Health.

Warren Kindzierski served as an Associate Professor in the University of Alberta Faculty of Engineering and School of Public Health (1996−2018) and as a Science Manager (Head, Chemical Risk Assessment) for the Alberta Department of Health (1993−1996). He has published/co-published more than 65 papers and 44 reports and has presented at more than 70 national and international technical conferences in North America over the past 25 years. He supervised 58 graduate students, post doctorates, and research associates during this time period. He was formerly a member of the American Conference of Governmental Industrial Hygienists and the American Industrial Hygiene Association and is a lifetime honorary member of the Canadian Institute of Public Health Inspectors. He has served or acted as an academic expert and/or advisor for public and private organizations across Canada on human health risk and environmental pollution issues.

Daniel Lauer is a Senior Associate Health Scientist with Cardno ChemRisk. He earned his MPH in environmental health from the University of Minnesota School of Public Health. He received a BS in biological sciences, with minors in chemistry and psychology, from the University of Denver. Lauer’s primary areas of training include epidemiology, environmental health, biostatistics, and risk assessment. During his graduate studies, Lauer focused on infectious and chronic disease epidemiology. Since joining Cardno ChemRisk, Lauer has applied his epidemiologic training to rigorously investigate the association between biologic, chemical, and physical agents and health outcomes. Specific areas of interest include improving methods in occupational epidemiology, the epidemiology and non-clinical safety of Electronic Nicotine Delivery Systems, and microbial risk assessments of food and consumer products.

Kenneth A. Mundt, a Senior Principal Health Scientist at Cardno ChemRisk, now Stantec, is an epidemiologist with professional interest and experience in applying epidemiological concepts and methods to understand human health risks from environmental, occupational, and consumer product exposures. He is a fellow of the American College of Epidemiology. He has designed, conducted, and published numerous epidemiological studies; performed critical reviews and syntheses of the published literature; and is active in the development of methods for integrating evidence across lines of evidence, including epidemiology, toxicology, and exposure science. Mundt specializes in the practical application of scientific concepts, methods, and evidence in evaluating disease causation; deriving health protective regulations; and for science-based evaluations for litigation and other decision-making purposes.

Martha Powers is an epidemiologist in the Center for Public Health and Environmental Assessment at the U.S. Environmental Protection Agency (EPA). Prior to joining EPA, she was a postdoctoral fellow at Northeastern University. She earned a PhD in environmental health sciences from the Johns Hopkins Bloomberg School of Public Health and an MPH and an MES at the University of Pennsylvania.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

Elizabeth Radke is an epidemiologist in the Integrated Risk Information System (IRIS) Program in the Office of Research and Development at the U.S. Environmental Protection Agency (EPA). She is the lead epidemiologist for the IRIS assessments of several per- and polyfluoroalkyl substances (PFAS) and has also contributed to IRIS work on phthalates, methyl mercury, hexavalent chromium, and vanadium, and EPA’s Office of Water assessments of other PFAS (PFOA and PFOS). She is a Co-Chair of the IRIS systematic review workgroup, which developed the IRIS Handbook. Prior to joining EPA, Radke received her PhD in epidemiology from the University of Florida and her MPH from the University of Pittsburgh and worked as a communicable disease epidemiologist for the Florida Department of Health and the Arlington County health department.

Anthony Russell is a Senior Associate Health Scientist with Cardno ChemRisk. He earned an MPH in chronic disease epidemiology from Yale University and a BS in chemical engineering from the University of Cincinnati. His research and academic training focused on organic chemistry, engineering methods, risk assessment, exposure assessment, epidemiology, and statistical analysis. He served in the U.S. Peace Corps in Lesotho, Africa, where he researched HIV mitigation and prevention as well as performed mathematics education. His thesis focused on food insecurity and its effect on chronic illnesses among refugees in Ghana. His research assisted local nongovernmental organizations in identifying culturally appropriate ways to deliver food baskets to refugee populations. He was contracted by the Centers for Disease Control and Prevention Foundation to work with the Connecticut State Department of Public Health as a COVID-19 Contact Tracing Team Lead. Throughout his graduate coursework and professional career, he has developed skills in statistical methods and modeling as well as assessing the public health impact of infectious and chronic illnesses.

William (Bill) Thompson is a Senior Epidemiology Consultant at Cardno ChemRisk, now Stantec. He has an MS in mathematics and a BS in biology and more than 20 years of experience in the application of epidemiological and statistical principles and methods to recognize, evaluate, and communicate health risks for legal and regulatory matters. Much of his experience has focused on general and specific causation of chronic diseases at varying exposure levels. Thompson has conducted and managed systematic reviews, provided analysis, written reports and delivered presentations for various projects, and published scientific papers on various cancer outcomes.

Jonathan Urban is a Managing Scientist and the Associate Director of the Health Sciences Practice with ToxStrategies, Inc., in Austin, Texas. Urban is a board-certified toxicologist with more than 15 years of experience studying and evaluating the potential health effects of a wide range of environmental and occupational chemicals of concern, consumer product ingredients, raw materials and impurities, and food-related compounds. He specializes in the use of evidence-based methods in support of hazard and risk assessment and is involved in the firm’s integration of these methods in the safety assessment development process. He has played an integral role in the firm’s efforts to develop and apply comprehensive systematic review methods for chemical risk assessment, with experience in all aspects of systematic review, including the use of critical appraisal tools for evaluating studies for risk of bias and external validity, as well as evidence integration. Urban has been involved with the critical evaluation and application of study quality tools (e.g., the National Toxicology Program’s Office of Health Assessment and Translation risk of bias, ToxRTool, SciRAP, the U.S. Environmental Protection Agency’s Office of Pollution Prevention and Toxics’ Toxic Substances Control Act tool, etc.) used in systematic review being developed and adopted by regulatory agencies for improving the scientific vigor and transparency of human health risk assessment. As such, he is well acquainted with the contemporary critical appraisal methods available for evaluating human health, animal toxicology, and in vitro experimental study data. Urban has published on the application of these methods and utilized this expertise in the development of critiques and recommendations regarding health-based toxicity criteria for both state and federal regulatory agencies, industry, and private-sector stakeholders. Urban is a Diplomate of the American Board of Toxicology, has published academic and professional studies in the peer-reviewed literature, and

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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is a reviewer for various scientific journals. While earning his PhD in toxicology at the University of North Carolina at Chapel Hill, Urban served as an enlisted communications specialist in the UA Marine Corps Reserves (Communications Company, Greensboro, North Carolina).

S. Stanley Young graduated from North Carolina State University with a BS, MES, and PhD in statistics and genetics. He worked in the pharmaceutical industry on all phases of pre-clinical research, first at Eli Lilly and then at GlaxoSmithKline. He has authored or co-authored more than 50 papers including 6 “best paper” awards and a highly cited book, Resampling-Based Multiple Testing. He has two issued patents. He is interested in all aspects of applied statistics, with special interest in chemical and biological informatics. He conducts research in the area of data mining. Young is a Fellow of the American Statistical Association and the American Association for the Advancement of Science. He is an Adjunct Professor of Statistics at North Carolina State University, the University of Waterloo, and the University of British Columbia, where he co-directs thesis work.

SESSION IV. CASE STUDIES OF TRIANGULATION ACROSS EPIDEMIOLOGY STUDIES FOR HAZARD IDENTIFICATION AND RISK ASSESSMENT

Amy Berrington de González is the Branch Chief of the National Cancer Institute’s (NCI’s) Radiation Epidemiology Branch and the Senior Advisor for Strategic Activities in the Division of Cancer Epidemiology and Genetics. She is an internationally recognized cancer epidemiologist who has made important contributions to the understanding of cancer risks from medical radiation exposures. Berrington de González is the Principal Investigator (PI) of the U.S. Pediatric Proton vs Photon Therapy Cohort and the Kaiser Breast Cancer Survivor Study and is the co-PI of the UK Pediatric CT Scans Cohort, which was the first epidemiological study to support a direct link between computed tomography (CT) scans and subsequent cancer risk. Berrington de González has participated in numerous national and international radiation and cancer advisory committees including the United Nations Scientific Committee on the Effects of Atomic Radiation, the National Academies, the Radiation Effects Research Foundation, and the International Agency for Research on Cancer. In 2019 she founded the International Society for Radiation Epidemiology and Dosimetry with a key goal of supporting capacity building and training of the next generation of radiation scientists, especially those from low- and middle-income countries. She is an elected member of the American Epidemiological Society and served on the editorial board of the American Journal of Epidemiology. Before joining NCI she held faculty positions at Oxford University and Johns Hopkins University.

Hanna Boogaard has more than 20 years of experience in air pollution epidemiology. She is a Consultant Principal Scientist at the Health Effects Institute (HEI) in Boston, Massachusetts, an independent research organization with balanced funding from the U.S. Environmental Protection Agency and motor vehicle industry. She received a PhD in 2012 in air pollution epidemiology from Utrecht University, Netherlands. She studied the health effects of traffic-related air pollution and the effectiveness of traffic policy measures. At HEI, she is involved in research oversight and the review of studies investigating the health effects of air pollution and studies evaluating the effectiveness of interventions to improve air quality and public health. In addition, she is involved in developing and overseeing new research programs on non-tailpipe traffic emissions, studies assessing adverse health effects of long-term exposure to low levels of ambient air pollution, and studies on the health effects of traffic-related air pollution. Furthermore, she is leading an HEI expert panel to systematically evaluate the evidence for the associations of long-term exposure to traffic-related air pollution with adverse human health outcomes. She holds an MSc in epidemiology and environmental health sciences (2005) from Maastricht University, Netherlands. Boogaard has been the advisor to the National Institute of Environmental Health Sciences, the World Health Organization, Health Canada, and other national and international bodies. She is an associate editor for Environment International and serves on the editorial review board for Environmental Health Perspectives. She is the Co-Chair of the International Society for Environmental Epidemiology (ISEE) Europe Chapter and a member of the ISEE Policy Committee.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

John W. Jackson is an Assistant Professor in the Departments of Epidemiology, Biostatistics, and Mental Health at the Johns Hopkins Bloomberg School of Public Health, and core faculty in the Johns Hopkins Center for Health Equity and the Center for Health Disparities Solutions. His research primarily focuses on developing methodological tools for translational health equity research. This research includes methods to identify high leverage targets and strategies for interventions that address health disparities, as well as methods to evaluate interventions and translate them to new populations and contexts, with current applications in health care and clinical prognosis. His work has been funded by a K01 award from the National Heart, Lung, and Blood Institute as well as pilot funding from Johns Hopkins University. He serves on the editorial boards of Epidemiology and Sociological Methods & Research.

David A. Savitz (NAM) is a Professor of Epidemiology in the Brown University School of Public Health, with joint appointments in obstetrics and gynecology and pediatrics in the Alpert Medical School. His epidemiological research has addressed environmental hazards in the workplace and community, reproductive health outcomes, and environmental influences on cancer. His research includes studies of miscarriage, preterm birth, and pregnancy complications, and he has addressed the health effects of nonionizing radiation, pesticides, drinking water treatment by-products, and perfluorinated compounds. Savitz is an elected member of the National Academy of Medicine and was awarded the David Rall Medal for Distinguished Leadership as Chair of Study Committee.

Roel Vermeulen is a Professor of Environmental Epidemiology and Exposome Science at the Institute for Risk Assessment Sciences at Utrecht University and at the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands. He is the Co-Chair of the Personalized Health and Medicine Program of Utrecht Life Sciences at Utrecht University and co-coordinates the preventive health program of the alliance between the Universities of Wageningen, Eindhoven, and Utrecht and the academic Medical Center Utrecht. He previously held positions at the National Cancer Institute in the United States. His scientific research focuses on environmental risk factors for cancer and cardiometabolic and neurological diseases through inter- and transdisciplinary research. One current research area is the exploration of new methods for quantifying the external and internal exposome. He coordinates the Dutch research program on the exposome (Exposome-NL), leads an EU project (EXPANSE) as part of the European Human Exposome Network, and coordinates the Dutch Hub of the European infrastructure on exposome research (EIRENE-NL). He is the Principal Investigator of several large case-control and prospective (biobank) studies in occupational and the general population. Vermeulen has served on many international committees including the World Health Organization and the U.S. National Toxicology Program. He is a member of the Dutch Health Council. He has published more than 700 publications.

SESSION VI. NEXT STEPS AND OPPORTUNITIES FOR APPLYING TRIANGULATION

Lisa Bero is a leader in evidence synthesis, meta-research, and the study of commercial determinants of health, focusing on tobacco control, pharmaceutical policy, and public health. She was the Co-Chair of Cochrane Governing Board from 2014 to 2018 and is currently the Senior Editor, Research Integrity and Cochrane Public Health and Health Systems Network. She has conducted systematic reviews and scoping and rapid reviews of human across multiple public health areas, including environmental health, and has led methods development to advance methods of systematic review in public health. Bero has chaired and served on committees related to conflicts of interest, evidence and decisions, and evidence synthesis for the National Academies, the International Agency for Research on Cancer, and the World Health Organization.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

Ellen T. Chang is a Principal Scientist and an epidemiologist in the Center for Health Sciences at Exponent, Inc., an international science and engineering consulting company in Menlo Park, California. She is also an Adjunct Associate Professor in the Department of Epidemiology & Biostatistics at the University of California, San Francisco, and a Visiting Professor at the Sun Yat-sen University Cancer Center in Guangzhou, China. Chang has conducted epidemiologic studies and systematic literature reviews of the risk of malignant lymphomas, nasopharyngeal carcinoma, hepatocellular carcinoma, and other cancers in association with a wide range of exposures, including infections, immunological biomarkers, occupational agents, industrial chemicals, medications and medical devices, reproductive factors, physical activity, alcohol and tobacco, diet and nutrition, and genetic variation. Chang earned her undergraduate degree at Harvard College in 1998 and her doctorate degree in epidemiology with a minor in biostatistics from the Harvard T.H. Chan School of Public Health in 2003. She completed a postdoctoral fellowship in medical epidemiology and biostatistics at the Karolinska Institute in Stockholm, Sweden, and she worked at the Cancer Prevention Institute of California and the Asian Liver Center at Stanford University before joining Exponent in 2012.

Lianne Sheppard is the Rohm & Haas Endowed Professor at the University of Washington School of Public Health with appointments in both biostatistics and environmental and occupational health sciences. Trained as a biostatistician, her research focuses on understanding the health effects of environmental and occupational exposures. She is particularly interested in how aspects of exposure assessment affect understanding of toxic exposures; her research ranges from the design of the exposure data collection to the modeling of exposure and subsequent epidemiologic inference. Her current research focuses on air pollution exposures and brain health. Sheppard has a strong personal commitment to research training at the interface between the environmental and quantitative sciences; research integrity; and diversity. She is the 2020 recipient of the International Society for Environmental Epidemiology Research Integrity Award, is the Chair of the U.S. Environmental Protection Agency’s (EPA’s) Clean Air Scientific Advisory Committee, and has served on various EPA special panels under the Clean Air Scientific Advisory Committee; the Integrated Risk Information System; the Federal Insecticide, Fungicide, and Rodenticide Act; and the Toxic Substances Control Act.

Martyn Smith is a Professor of Toxicology and the Kaiser Endowed Chair of Cancer Epidemiology in the Division of Environmental Health Sciences in the School of Public Health at the University of California, Berkeley. He received a PhD in biochemistry from St. Bartholomew’s Hospital in London and did postdoctoral training in toxicology at the Karolinska Institute in Stockholm. Smith is a laboratory scientist with expertise in molecular epidemiology, toxicology, and genomics, and his research is aimed at finding the causes of chronic diseases, including cancer and diabetes. He currently teaches toxicology and health risk assessment and mentors graduate students and postdoctoral scholars in the Molecular Toxicology, Epidemiology, and Environmental Health Science programs. Smith is a Fellow of the American Association for the Advancement of Science. He received the 2010 Children’s Environmental Health Network Award, became an Elected Fellow of the Collegium Ramazzini in 2012, and received the Alexander Hollaender Award from the Environmental Mutagenesis and Genomics Society in 2014. Since its inception in 1987, Smith has directed the Superfund Research Program Center at the University of California, Berkeley. This program combines basic research, engineering, population studies, training, and community engagement to understand cumulative impacts from multiple environmental stressors. Smith is best known for his work on benzene toxicity, the exposome concept, and the key characteristics framework, which helps risk assessors better identify, organize, and summarize the potential health risks of different chemicals. His most recent work uses machine learning, artificial intelligence, and molecular modeling to predict toxicity.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

Kyla W. Taylor is a Health Scientist in the Integrative Health Assessment Branch at the Division of the National Toxicology Program (DNTP) at the National Institute of Environmental Health Sciences. Taylor serves as a member of DNTP’s Consumer Products and Therapeutics Program Management Team, and her work includes conducting systematic reviews and meta-analyses, developing and promoting harmonization of systematic review methods, and understanding how personal care product use is related to sociodemographic characteristics, early puberty, breast cancer, and other health outcomes. Taylor joined DNTP in 2009. She received her BA from St. Olaf College, her MS in population health sciences from the University of Wisconsin–Madison, and her PhD in epidemiology from the University of North Carolina at Chapel Hill.

Tracey Woodruff is the Director of and the Alison S. Carlson Endowed Professor for the Program in Reproductive Health and the Environment and is a Professor in the University of California, San Francisco (UCSF), Department of Obstetrics, Gynecology and Reproductive Sciences and the Philip R. Lee Institute for Health Policy Studies. She is the Director of a newly awarded grant by the National Institute of Environmental Health Sciences’ Environmental Health Core Center to the UCSF Environmental Research and Translation for Health Center. She is a recognized expert on environmental pollution exposures and impacts on health, with a focus on pregnancy, infancy, and childhood, and her innovations in translating and communicating scientific findings for clinical and policy audiences. She has authored numerous scientific publications and book chapters, and has been quoted widely in the press, including USA Today, the San Francisco Chronicle, and The New York Times. Before joining UCSF, Woodruff was a senior scientist and policy advisor for the U.S. Environmental Protection Agency’s Office of Policy. She was appointed by the governor of California in 2012 to the Science Advisory Board of the Developmental and Reproductive Toxicant Identification Committee.

Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×

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Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
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Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
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Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
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Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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Page 49
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
Page 50
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
Page 51
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
Page 52
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
×
Page 53
Suggested Citation:"Appendix B: Speaker and Poster Presenter Biographies." National Academies of Sciences, Engineering, and Medicine. 2022. Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/26538.
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Page 54
Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop Get This Book
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 Triangulation in Environmental Epidemiology for EPA Human Health Assessments: Proceedings of a Workshop
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Human health risk assessments provide the basis for public health decision-making and chemical regulation in the United States. Three evidence streams generally support the development of human health risk assessments - epidemiology, toxicology, and mechanistic information. Epidemiologic studies are generally the preferred evidence stream for assessing causal relationships during hazard identification. However, the available studies may be limited in scope, subject to bias, or otherwise inadequate to inform causal inferences. In addition, there are challenges in assessing coherence, validity, and reliability during synthesis of individual epidemiological studies with different designs, which in turn affects conclusions on causation.

Triangulation aims to address the challenge of synthesizing evidence from diverse studies with distinct sources of bias. Bias is a systematic error that leads to inaccurate study results. Tools for assessing risk of bias provide a structured list of questions for systematic consideration of different domains (such as confounding, selective reporting, and conflict of interest). These tools also provide a structured framework for identifying potential sources of bias and informing judgments on individual studies. The National Academies of Sciences, Engineering, and Medicine convened a workshop to understand and explore triangulation and opportunities to use the practice to enhance the EPA's human health assessments. The workshop was held virtually on May 9 and 11, 2022. This publication summarizes the key presentations and discussions conducted during the workshop.

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