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Suggested Citation:"2021 Meetings." National Academies of Sciences, Engineering, and Medicine. 2022. Forum on Regenerative Medicine: 2021 Annual Report. Washington, DC: The National Academies Press. doi: 10.17226/26583.

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2021 Meetings February 23–24, 2021 (virtual) The meeting covered topics related to new developments in the field including the following: regulatory updates related to regenerative medicine, recent progress in gene therapy, opportunities for decentralized clinical trials in regenerative medicine, and state-level policies around unproven stem cell offerings. The meeting also featured an educational session on the role of the immune system in regenerative medicine to help inform members as they developed the public workshop on this topic for late 2021. June 14–15, 2021 (virtual) In addition to updates from forum members, the meeting included updates from the National Academies’ activities related to COVID-19 and organoids. The meeting included a session on expanding the training infrastructure to better support the regenerative medicine workforce and a session exploring stem cell offerings at academic medical centers, with the goal of better understanding the scope and context in which stem cells are being used for orthopedic applications. November 2–3, 2021 (virtual) Understanding the Role of the Immune November 10, 2021 (virtual) System in Improving Tissue Regeneration – At this meeting, members debriefed following the A Workshop public workshop, Understanding the Role of the Immune System in Improving Tissue Regeneration, and discussed next steps. In addition, the forum launched a strategic planning initiative that will continue into 2022 to chart the group’s path forward for the next 3–5 years. 2021 Annual Report | 3

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The National Academies of Sciences, Engineering, and Medicine's Forum on Regenerative Medicine (the forum) provides a convening mechanism for interested parties from academia, industry, government, patient and provider organizations, regulatory bodies, foundations, societies, associations, and others. The forum identifies existing and potential barriers to scientific and therapeutic advances; discusses opportunities to assist in facilitating more effective partnerships among key stakeholders; examines the impact that current policies have on the discovery, development, and translation of regenerative medicine therapies; considers the unique challenges of identifying, validating, and bringing regenerative medicine applications to market; and explores the ethical, legal, and social issues posed by advances in regenerative medicine.

During 2021, the forum members continued to focus on two broad areas through their two working groups: Regenerative Engineering and Gene Therapy and Systems Thinking. The members and staff also continued to explore challenges and discuss possible solutions in a number of other areas relevant to the development of regenerative medicines, including communication, workforce development, cost of and access to therapies, and regulatory and legislative affairs. This publication describes the activities of the forum during 2021.

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