National Academies Press: OpenBook
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

Image

Sponsor Influences on the
Quality and Independence of
Health Research

______

Dara Rosenberg, Elizabeth Boyle,
Alexandra McKay, and Joe Alper,
Rapporteurs

Board on Population Health and Public
Health Practice

Board on Health Sciences Policy

Health and Medicine Division

Proceedings of a Workshop

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001

This activity was supported by contracts between the National Academy of Sciences and the Gordon and Betty Moore Foundation and Rita Allen Foundation. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.

International Standard Book Number-13: 978-0-309-70352-9
International Standard Book Number-10: 0-309-70352-2
Digital Object Identifier: https://doi.org/10.17226/27056

This publication is available from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.

Copyright 2023 by the National Academy of Sciences. National Academies of Sciences, Engineering, and Medicine and National Academies Press and the graphical logos for each are all trademarks of the National Academy of Sciences. All rights reserved.

Printed in the United States of America.

Suggested citation: National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor influences on the quality and independence of health research: A workshop. Washington, DC: The National Academies Press. https://doi.org/10.17226/27056.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

The National Academy of Sciences was established in 1863 by an Act of Congress, signed by President Lincoln, as a private, nongovernmental institution to advise the nation on issues related to science and technology. Members are elected by their peers for outstanding contributions to research. Dr. Marcia McNutt is president.

The National Academy of Engineering was established in 1964 under the charter of the National Academy of Sciences to bring the practices of engineering to advising the nation. Members are elected by their peers for extraordinary contributions to engineering. Dr. John L. Anderson is president.

The National Academy of Medicine (formerly the Institute of Medicine) was established in 1970 under the charter of the National Academy of Sciences to advise the nation on medical and health issues. Members are elected by their peers for distinguished contributions to medicine and health. Dr. Victor J. Dzau is president.

The three Academies work together as the National Academies of Sciences, Engineering, and Medicine to provide independent, objective analysis and advice to the nation and conduct other activities to solve complex problems and inform public policy decisions. The National Academies also encourage education and research, recognize outstanding contributions to knowledge, and increase public understanding in matters of science, engineering, and medicine.

Learn more about the National Academies of Sciences, Engineering, and Medicine at www.nationalacademies.org.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

Consensus Study Reports published by the National Academies of Sciences, Engineering, and Medicine document the evidence-based consensus on the study’s statement of task by an authoring committee of experts. Reports typically include findings, conclusions, and recommendations based on information gathered by the committee and the committee’s deliberations. Each report has been subjected to a rigorous and independent peer-review process and it represents the position of the National Academies on the statement of task.

Proceedings published by the National Academies of Sciences, Engineering, and Medicine chronicle the presentations and discussions at a workshop, symposium, or other event convened by the National Academies. The statements and opinions contained in proceedings are those of the participants and are not endorsed by other participants, the planning committee, or the National Academies.

Rapid Expert Consultations published by the National Academies of Sciences, Engineering, and Medicine are authored by subject-matter experts on narrowly focused topics that can be supported by a body of evidence. The discussions contained in rapid expert consultations are considered those of the authors and do not contain policy recommendations. Rapid expert consultations are reviewed by the institution before release.

For information about other products and activities of the National Academies, please visit www.nationalacademies.org/about/whatwedo.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

PLANNING COMMITTEE FOR A WORKSHOP ON SPONSOR INFLUENCES ON THE QUALITY AND INDEPENDENCE OF HEALTH RESEARCH1

LONNIE KING (Chair), Academy Professor and Dean Emeritus, the Ohio State University College of Veterinary Medicine

C. K. GUNSALUS, Director, National Center for Principled Leadership and Research Ethics, University of Illinois Urbana-Champaign

AARON KESSELHEIM, Professor of Medicine, Harvard Medical School

ROSS MCKINNEY, Chief Scientific Officer, Association of American Medical Colleges

FAITH MITCHELL, Institute Fellow, Urban Institute

LANA SKIRBOLL, Sanofi (retired)

CATHERINE WOTEKI, Visiting Distinguished Institute Professor, University of Virginia Biocomplexity Institute, and Professor of Food Science and Human Nutrition, Iowa State University

Staff

ELIZABETH BARKSDALE BOYLE, Project Director (from October 2022) Senior Program Officer

ROSE MARIE MARTINEZ, Senior Board Director

ALEXANDRA MCKAY, Research Associate

Y. CRYSTI PARK, Program Coordinator

DARA ROSENBERG, Associate Program Officer

KATHLEEN STRATTON, Project Director (until October 2022) and Scholar

CLARE STROUD, Senior Board Director

Consultants

JOE ALPER, Science Writer

___________________

1 The National Academies of Sciences, Engineering, and Medicine’s planning committees are solely responsible for organizing the workshop, identifying topics, and choosing speakers. The responsibility for the published Proceedings of a Workshop rests with the workshop rapporteurs and the institution.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

This page intentionally left blank.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

Reviewers

This Proceedings of a Workshop was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine (the National Academies) in making each published proceedings as sound as possible and to ensure that it meets the institutional standards for quality, objectivity, evidence, and responsiveness to the charge. The review comments and draft manuscript remain confidential to protect the integrity of the process.

We thank the following individuals for their review of this proceedings:

ARAMANDLA RAMESH, Meharry Medical College

GARY RUSKIN, U.S. Right to Know

Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the content of the proceedings nor did they see the final draft before its release. The review of this proceedings was overseen by Lawrence J. Appel, Johns Hopkins University. He was responsible for making certain that an independent examination of this proceedings was carried out in accordance with standards of the National Academies and that all review comments were carefully considered. Responsibility for the final content rests entirely with the rapporteurs and the National Academies.

We also thank staff member Jennifer Heimberg for reading and providing helpful comments on this manuscript.

Page viii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

This page intentionally left blank.

Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page xiii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×

Acronyms and Abbreviations

ABA American Beverage Association
AHRQ Agency for Healthcare Research and Quality
AI artificial intelligence
COI conflict of interest
CSR NIH Center for Scientific Review
EPA Environmental Protection Agency
EPC AHRQ Evidence-Based Practice Center
FDA Food and Drug Administration
GRADE Grading of Recommendations Assessment, Development and Evaluation
HEI Health Effects Institute
HHS Department of Health and Human Services
IARC International Agency for Cancer Research
ILSI International Life Sciences Institute
NIH National Institutes of Health
NTP National Toxicology Program
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
OER NIH Office of Extramural Research
OSHA Occupational Safety and Health Administration
PCORI Patient-Centered Outcomes Research Institute
PFAS per and polyfluoroalkyl substances
PFOA perfluorooctanoic acid
UCSF University of California, San Francisco
USDA United States Department of Agriculture
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R1
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R2
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R3
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R4
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R5
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R6
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R7
Page viii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R8
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R9
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R10
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R11
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R12
Page xiii Cite
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R13
Suggested Citation:"Front Matter." National Academies of Sciences, Engineering, and Medicine. 2023. Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/27056.
×
Page R14
Next: 1 Introduction »
Sponsor Influences on the Quality and Independence of Health Research: Proceedings of a Workshop Get This Book
×
Buy Paperback | $23.00 Buy Ebook | $18.99
MyNAP members save 10% online.
Login or Register to save!
Download Free PDF

Governments, philanthropic organizations, and private industry fund human health and medical research. Various funding sources might bias research so that the results are more favorable to their agents. Funders may influence investigative scope, specific questions posed, experimental design, and principal investigator appointments. Reporting, analysis, dissemination, and communication and data availability, reanalysis, and replication can also experience bias from a funding source. To explore structures, processes, and principles to ensure high-quality health research independent of sponsor influence, the National Academies Board on Population Health and Public Health Practice and the Board on Health Sciences Policy hosted a public virtual workshop in December 2022 that examined the sources of funding for health research and evidence on whether they influence the quality and outcomes of resulting health research. The workshop also discussed models, process, and principles used to protect the independence and quality of research. This Proceedings summarizes the discussions held during the workshop.

  1. ×

    Welcome to OpenBook!

    You're looking at OpenBook, NAP.edu's online reading room since 1999. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

    Do you want to take a quick tour of the OpenBook's features?

    No Thanks Take a Tour »
  2. ×

    Show this book's table of contents, where you can jump to any chapter by name.

    « Back Next »
  3. ×

    ...or use these buttons to go back to the previous chapter or skip to the next one.

    « Back Next »
  4. ×

    Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book.

    « Back Next »
  5. ×

    Switch between the Original Pages, where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text.

    « Back Next »
  6. ×

    To search the entire text of this book, type in your search term here and press Enter.

    « Back Next »
  7. ×

    Share a link to this book page on your preferred social network or via email.

    « Back Next »
  8. ×

    View our suggested citation for this chapter.

    « Back Next »
  9. ×

    Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available.

    « Back Next »
Stay Connected!