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Biographical Memoirs: Volume 53 (1982)

Chapter: Roger Adams

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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Suggested Citation:"Roger Adams." National Academy of Sciences. 1982. Biographical Memoirs: Volume 53. Washington, DC: The National Academies Press. doi: 10.17226/576.
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Biographical :7Vfemoirs VOLUME 53

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ROGER ADAMS January 2, 1889-July 6, 1971 BY D. STANLEY TARBELL AND ANN TRACY TARBELL ROGER ADAMS was for a generation the leacling organic chemist in the United States. In addition to publishing outstanding research in structural chemistry anti stereo- chemistry and to training about 250 Ph.D.'s and postdoc- torates at Illinois, he player! a key role in the development of graduate education in science. His influence on the growth of industrial chemical research was great, both personally and through the students he trained. His services to the country in two world wars and to the scientific community brought him the role of scientific statesman on the world scene. He combined personal qualities of charm, strength, high intelli- gence, and extraordinary capacity for hard work. Roger Adams was a direct descendant of the uncle of President John Adams; his ancestors had moved to south- eastern New Hampshire, where Roger's father, Austin W. Adams (1845-1916), was born. Austin taught in a country school, then movect to Boston in IS72, where he was asso- ciated with the Old Colony and New Haven Railroads for the rest of his life. In 1880 he married Lydia Curtis from Jamaica Plain, likewise a school teacher, who was related to numerous business and literary figures in Boston and was clescencled from early colonial settlers. The Adamses lived for twenty years on Worcester Street 3

4 BIOGRAPHICAL MEMOIRS in the then attractive residential section of South Boston. Austin Adams, a kink! father and a man with scholarly avoca- tions, supported his family on a comfortable but not lux- urious scale. Roger was the last child in a family with three daughters, and he apparently had a happy boyhood. Two of Roger's sisters—tall, athletic, and gifted graduated from Racicliffe and the third from Smith. The family moved to Cambridge in 1900, probably to be nearer the colleges. After preparation at Boston Latin anct Cambridge Latin, Roger entered Harvard in 1905. His first years were un- distinguished acaclemically, but he completed the require- ments for his A.B. in chemistry in three years, earning high grades in his major courses in chemistry and in his minor of mining. His interest in chemistry may have been aroused by C. L. ~ackson's course on "the chemistry of common life," which he took in his first year. He worked very hard at a series of demancling courses and had the satisfaction of re- ceiving a John Harvard honorary scholarship for making four A's. In his last unclergracluate year he took advanced courses anti started research in organic chemistry with H. A. Torrey. After graduation in 1909, he worked for his Ph.D., aided by a teaching assistantship at Radcliffe. Torrey cliecl prematurely in 1910, anct Adams completed his thesis with the help of Jackson, Latham Clarke, ant! G. S. Forbes. Among his fellow graduate students in 1911 ant! 1912 were E. K. Bolton ("Keis," a close friend), Farrington Daniels, Frank C. Whitmore, and James B. Sumner. James B. Conant was then an unclergraduate. As an outstanding Ph.D. of 1912, Aciams was awarded a Parker Traveling Fellowship for 1912 and 1913, which he spent partly in the laboratory of Emil Fischer with Otto Diels at Berlin and partly with the brilliant Richard WilIstatter in the latter's new laboratory in DahIem, near Berlin. A ticket stub among Adams' papers shows that he took a Zeppelin

ROGER ADAMS flight from Potsdam to Berlin; he also traveled in Finland, Russia, ant! Sweden. Although it resulted! in no scientific papers, Adams' Euro- pean year was the beginning of his lifelong interest in 5 , , ~ At_ European science and scientists. He clearly found the Euro- pean university system clistasteful; one professor in each department or institute controlled absolutely the activities of all research students and junior staff members. This attitude is reflected in Adams' leadership of the Illinois department along more democratic lines, which provided a mode] for other graduate science departments in American universi- ties. Adams' policy of helping his junior colleagues develop inclepenclent research careers was emphasized further in 1954, when he clesigne`1 the program for the Sloan Founcla- tion that gave unrestricted grants to promising younger workers. As a result of his foresight, generations of young American scientists are in his debt. Adams returned to Harvard in 1913 as research assistant to C. L. Jackson at $800 a year and shortly undertook the duties of instructor in chemistry. Along with other courses he taught elementary organic chemistry and initiated the first elementary laboratory in that subject at Harvard. He was a very successful teacher, so much so that James B. Conant, who succeeded him, die! so with some trepidation about his own ability to interest an elementary class in organic chem- istry. During his three years on the Harvard faculty, Adams not only carried a very heavy formal teaching load at Har- varcl and Radcliffe, but made a strong start on his own re- search program. In 1916 Adams accepted an offer from William A. Noyes, head of the Illinois Chemistry Department, to become assis- tant professor at a salary of $2,\800 per year. He was ambi- tious to accomplish something notable in science; he un- doubtedly saw that the Illinois department, aIreacly well

6 BIOGRAPHICAL MEMOIRS known for its research and teaching under Noyes' leadership, offered greater opportunities than Harvard, as well as better laboratory facilities and the challenge of a position outside New England. He took the position at Illinois with no reser- vations and with the determination to develop his own research program and that of the department. Urbana re- mained his home for the rest of his life, in spite of many attractive offers to move to industry or university positions, including MIT and Harvard. It is indicative of his personal dedication to Illinois as his residence that he later joined the Rotary Club and served as its president in 1932. At TIlinois Adams took charge of the important "prep labs" started by his predecessor, C. G. Derick, for the syn- thesis of essential organic chemicals cut off by the blockade of Germany. This was expanded and, with the help of graduate students, particularly E. H. Volwiler and C. S. (Speed) Mar- vel, over 100 key compounds were made available for sale and for use in Illinois. Adams reorganized the operation, introduced strict cost accounting procedures, and made it a financial as well as scientific success. The tested procedures developed in "preps" (officially called Organic Chemical Manufactures) led to the indispensable annual publication, Organic Syntheses, of which fifty annual volumes were pub- lished under Adams' watchful eye. Conant later said that the publication should have been named "Adams Annual," . . . because he was the moving spirit. At Urbana Adams pursued research vigorously on the preparation of local anaesthetics with Oliver Kamm of the Illinois faculty and became a consultant to Abbott in 1917, a relationship that lasted on a formal basis until the 1960's. E. H. Volwiler, his first Ph.D., joined Abbott as a research chemist in 1918. Adams was drawn into research for the army in 1917 and, with other chemists, worked on problems connected with war

ROGER ADAMS 7 gases at American University in Washington, D.C. Adams and Conant headed research groups, and E. P. KohIer, Adams' old faculty friend from Harvarcl, was in charge of the Offense Section. Adams spent the last few months of 1918 in uniform as a major. He was recognized by Conant as the leading figure in the group. Adams was married to Lucile Wheeler on August 29, 1918 at White River {unction, Vermont. Mrs. Adams came from a well-known Vermont family; she was a Mount Holy- oke graduate, had studiecI dietetics at Columbia, and tract taught home economics at TIlinois. They tract one child, Lu- cile, and there are four grandchildren, in whom Aciams clelighted, particularly in his retirement years. The Adamses soon moved to a large house at 603 West Michigan, Urbana, where many guests, students and ctistinguished visitors alike, were graciously entertained by Mrs. Aciams. This house was Adams' headquarters for the rest of his life. He wrote fre- quently to Mrs. Adams when he was away; he had a gift for light verse and sent a rhymed valentine to her and their daughter each year. Adams' return to Urbana was followed by intensive re- search with a large number of Ph.D. students ancI by many outstanding scientific publications. From 1918 through 1926 he publishect seventy-three scientific papers and trained forty-five Ph.D.'s, including E. H. Volwiler, I. R. Johnson, A. W. Ingersoll, S. M. McEIvain, W. H. Carothers, W. R. Brode, C. R. Noller, R. L. Shriner, C. F. Rassweiler, and many others who became well known in academic or industrial chemistry. This was in spite of a very serious illness in 1924, recovery from which required nearly a year. During this time he took up stamp collecting, a hobby he pursued for many years with characteristic thoroughness ancl enthusiasm. The important problems he worked on during his re- search career included the development of platinum oxide

8 BIOGRAPHICAL MEMOIRS for catalytic hydrogenation (Adams catalyst—discovered by an excellent example of serendipity), local anaesthetics, syn- thesis of naturally occurring anthraquinones, structure and synthesis of chaulmoogric acid (used at that time in treating leprosy), stereochemistry of compounds with restricted rota- tion and of deuterium compounds, the structure of gossypo} (the yellow material in cottonseed meal), compounds isolated from marihuana, and the structure of the Crotalaria and Senecio alkaloids and quinoneimines. The gossypo] structure was perhaps the most difficult, but the voluminous cor- respondence related to his work on marihuana illustrates well the administrative and scientific ability and the bound- less energy and enthusiasm with which he pursued his researches. As a body, Adams' research represents the high point of structural organic chemistry, particularly on natural prod- ucts, before the Instrumental Revolution and before the emergence of physical organic chemistry as a major field. He was elected to the National Academy of Sciences in 1929. In 1926 Adams was chosen unanimously to succeed! W. A. Noyes as head of the Chemistry Department at Illinois. By this date the department was recognized as one of the leaders in organic chemistry, and the characteristic features of Adams' conception of a graduate department were clear. The faculty should be of outstanding ability: Adams, Marvel, R. L. Shriner, R. C. Fuson, and, in the 1930's and later, H. R. Snyder, C. C. Price, N. J. Leonard, and their junior col- leagues formed the organic group, with few changes. Equip- ment and facilities were to be kept up to date; graduate students and undergraduates were carefully selected ancT were caught up in the infectious enthusiasm and hard work of the faculty so that they, too, worked long hours. Research was carefully done? carefully and promptly prepared for publication, and great attention was paid to placing graduates

ROGER ADAMS 9 in suitable positions. Adams was actively interested in the progress of all Illinois graduates in chemistry after they left Urbana and recommended them for new positions as the occasion arose; his remarkable memory enabled him to call most of them by name, whoever had directed their research. Adams developed a highly successful scheme for direct- ing graduate student research. By starting a student on a problem that promised reasonable success and by publishing the work promptly, he built up the stuclent's confidence to undertake more difficult experiments. Such problems as hin- dered rotation in biphenyIs offered indispensable and excel- lent training in synthesis and physical measurements, and clifficult investigations in natural products were usually given to experienced graduate students or to postdoctorates. Adams' personal magnetism macle interesting even the drudgery encountered in research projects, and macle good results exciting. His buoyant and forward-Iooking nature, his outgoing personality, his interest in people as individuals, and his breadth of knowledge and experience made conver- sation with him amusing and delightful, broadly eclucational in the best sense. Aclams' work on Organic Syntheses, his circulation of bound volumes of reprints to leacling universities here and abroad, and his active participation in scientific societies increased the reputation of his department. What he had really accom- plished by 1930 was the development of a graduate clepart- ment of national stature that had strength in all significant fields of chemistry; it represented a novel addition to that characteristic American educational institution, the land- grant college. Although A. A. Noyes at MIT (later at Caltech) and G. N. Lewis at Berkeley hac! built up departments of physical chemistry with several outstanding colleagues, the Illinois department was larger and offered a broader range of research opportunities to students.

10 BIOGRAPHICAL MEMOIRS The growth and research output of the Illinois depart- ment are shown by a survey of papers in organic chemistry in the Journal of the American Chemical Society. In the twenty-five years from 1914 through 1939, Illinois was surpassed only four times in number of publications of organic research, advancing from four papers in 1914 to sixty-six papers in 1939, Il percent of all organic papers published in this journal from all the nation's laboratories in ~ 939. The Illinois papers were scientifically of high quality. Although figures available do not give cloctorates for organic chemistry as such, cluring the years 1920 through 1939 Illinois producer! 346 Ph.D.'s in chemistry, 6 percent of all American Ph.D.'s in this field. Adams clirected almost one-third of the TIlinois total ant! accounted for about 2 percent of those in the whole country for the years 1920 through 1939, as shown in the following table; during the li920's Adams trained 3 percent of the American Ph.D.'s in all fields of chemistry. Doctorates Granted in All Fields of Chemistry, 1920-1939 Years Illinorsa Total US 192~1924 64 (30) 746 1925-1929 73 (26) 1,178 193~1934 103 (25) 1,751 1935-1939 106 (22) 2,212 a Figures in parentheses represent Adams' own Ph.D.'s for these periods. Of the 105 Ph.D.'s trained by Adams during the years 191~ through 1939 inclusive, seven were women; of the total, fifty-nine spent most or all of their careers in inclustrial re- search, twenty-six were in teaching, and nine worked in gov- ernment laboratories. The remainder included a number of overseas students. Where did all of these chemists find jobs? Consideration of this question leads to Roger Adams' interaction with the

ROGER ADAMS 11 industrial chemical research community, which grew strik- ingly between the two florid wars. It is estimates! that in ~ 920 there were 300 industrial research laboratories in the United States, and that in 1940 the number had grown to 2,200. In 1927 the chemical industry is believed to have hac! 3,300 research people, and in 193S, in spite of the depression, the number had increased to 9,542. Adams had a natural inclination toward the business worm; although he always regarded] himself as a member of the academic profession, he understood finance and business and was liked and trustee! by businessmen. He served as consultant for A. E. Staley Co., M. W. Kellogg Co., and Coca-Cola, as well as Abbott, and he and Marvel became consultants for DuPont in 1928. Industrial research was given a large boost by the spectacular success of Adams' bril- liant student, Wallace H. Carothers, whose funciamental re- search on polymers at DuPont from 1928 to 1937 resulted in the discovery of nylon and neoprene rubber. Adams, always close to him, was deeply affected by his death in 1937. Adams frequently wrote and spoke about what industry was entitled to expect from its research chemists, and the majority of Illinois Ph.D.'s who clid go into industrial research were well informed as graduate students in this regard. Con- versely, he was able to make clear to research management in industry how research chemists should be treated to maintain good morale and productivity. As the number of Illinois Ph.D.'s grew, it was a small educational or industrial labora- tory that did not have one or more. Hence, the influence of the Illinois department and its graduates became very great, particularly when many of these graduates reached respon- sible administrative positions in research and teaching. Adams was constantly being asked for advice about academic and industrial positions everywhere, and he spent much ef- fort in fancying suitable positions for his students. In 1954 he

12 BIOGRAPHICAL MEMOIRS wrote that his "biggest contribution to chemical industry has been very indirect through many of the students who have been eminently successful in industry." It is clear, however, that this underestimates his personal contribution. Although it is almost invidious to single out Adams' Ph.D.'s between 1927 and 1959, the following had outstand- ing careers: M. M. Brubaker, R. M. Joyce, T. L. Cairns, I. F. Hycle, W. M. Stanley (Nobel Laureate), W. E. Hanford, Byron Riegel, R. Clarke Morris, Allene R. leads, B. R. Baker, Nathan Kornblum, R. S. Long, M. W. Miller, lack Hine, W. H. Lycan, M. T. Leffler, E. E. Gruber, D. I. Butter- baugh, R. O. Saner, ant] R. B. Wearn. An equally impressive list could be made of his postdoctorates. Adams played a key role in the enlistment of unrestricted industrial support for university research, which became par- ticularly significant after World War IT; this was sometimes in the form of graduate fellowships, of which there were many at Illinois even before World War Il. ant] sometimes as unrestricted grants to be used for equipment or stipends as needecl. In acIdition, his service for the National Science Foundation, the Sloan Foundation, the Welch Foundation, and the SIoan-Kettering Institute for Cancer Research, among others, increased the influence of his ideas. His atti- tude in distributing research funcis was the same as in his selection of faculty members or graduate students: pick the best people possible, give them what they need to work, and don't bother them unduly. Several points previously mentioned bear on Adams as an international scientific figure. His acquaintance with Euro- pean chemistry from his postdoctoral trip in 1912 and 1913 was maintained and increased by extensive correspondence. His papers contain a series of letters written in 1927 acknowI- edging copies of Illinois reprints from numerous distin- guished European chemists and many Americans, and his

ROGER ADAMS 13 home guest book contains the names of eminent scientists from all around the world. He maintained a cordial corre- sponclence with nearly all prominent foreign chemists, in- clucling numbers from South America, South Africa, and the Far East, and many of them visited Urbana. In 1936 he visited many countries in Europe and greatly increased his professional acquaintances, especially in SwitzerIanc3. During his war years of work for the National Defense Research Committee, 1940 to 1945, Adams was in charge of many projects in chemistry ant! chemical engineering, requiring constant travel in this country to laboratories and proving grounds. In 1943 he visited Britain, where he renewed several oIcl acquaintances ant! met many clistin- guished British scientists whom he had not seen before. He returned to Urbana when possible to talk with his students. One of his associates in Washington during those years wrote that if he was shipwrecked on a distant island, he would like to have Roger Adams with him. He was sure that Adams would figure out some way of getting off, and they "would have a whale of a good time doing it."* After the war he was in Berlin, from November 1945 until February 1946, as scientific advisor to the U.S. Military Gov- ernment under General Lucius D. Clay, where he exercised significant influence in reviving the German compendia, Beilstein and Gmelin. He also visited Japan twice with com- mittees of scientists, and the ensuing plan for a complete reorganization of Japanese science resultec! in its rebuilcling along more democratic lines. His group had a long confer- ence with General MacArthur who strongly commencled their report ant! used it as a basis for scientific policy in Japan. Although he retired as department head at Illinois in 1954, and as research professor in 1957, he continued his *W. M. Latimer to N. A. Parkinson, 20 October 1949.

4 BIOGRAPHICAL MEMOIRS work with Organic Syntheses and Organic Reactions, which he had started about 1940, and as a consultant; he was on acI- visory boards for many groups, some mentioned above, and for the American Chemical Society, of which he had been president in ~ 935. He was president of the American Associa- tion for the Advancement of Science, served on the Natural Resources Board of the State of Illinois, and on the Board of Directors of Battelle Memorial Institute. His retirement as head of chemistry in 1954 was cele- brate(1 by a symposium in Urbana, attended by over 300 former students, colleagues, anc! friends. The group showed its great affection for Aciams, and some of his students wrote a suitably irreverent skit, poking fun at some of his foibles. Adams macle many overseas trips, partly for pleasure and partly to attend international scientific meetings; he visited most of the major countries of the worI(1 at least once, and enlarged his circle of acquaintances in every country. As a senior statesman of American science, his visits were major events everywhere. After Mrs. Adams' death in 1964, he continued an active schedule of attending meetings, serving on boards of directors, anct traveling, even in his late seven- ties. One of his colleagues, asked if Adams was working less after his retirement, said he probably was; he was cloing only three men's work instead of four.* He cTied on July 6, 1971 after a brief hospitalization, following a trip to Columbus for a directors' meeting at Battelle Memorial Institute. Adams' accomplishments had been recognized by the re- spect and personal affection of his collaborators and asso- ciates. He was a member of the American Philosophical So- ciety, the American Academy of Arts ant! Sciences, ant! an honorary member of more than a dozen foreign academies and chemical societies. He received honorary doctorates *C. S. Marvel to E. H. Volwiler, 12 November 1958.

ROGER ADAMS 15 from ten institutions, including TIlinois, Harvarcl, Yale, Rochester, Pennsylvania, and Michigan. He was the recipient of most of the medals and awards open to scientists, such as the Davy Medal of the Royal Society, the Gibbs, Nichols, Parsons, and Priestly medals, the Mecial of the Franklin In- stitute, the National Medal of Science, Honorary Com- mander of the British Empire (C.B.E.), and the Mecial for Merit of the Uniter! States, the last two recognizing his ser- vices in World War Il. The list of his awards, offices, and honors covers three pages. More than any other organic chemist of his time, Roger Adams epitomized the coming of age of organic research and advanced training in this country and the phenomenal growth of chemical research ant! production in industry. His influence on the development of American science rested partly on the period in which he lived, but to a greater extent on his own extraordinary personality and ability. Roger Adams is a good example of Dr. Samuel Johnson's definition of genius: "a mind of large general powers, accidentally determined to some particular direction." THE BASIS OF THIS PAPER is the research for a book-length biog- raphy of Adams by the present authors, now in press. Some of the travel and other costs of this research were paid by grants from the Centennial Fund of Vanderbilt University, the Petroleum Research Fund, and the National Science Foundation. We are indebted to Lucile Adams Brink for gracious assistance and for the loan of family documents. Maynard G. Brichford of the University of Illi- nois Archives and lean R. St. Clair of the National Academy of Sciences have been most helpful with the Adams documents under their care. Drs. E. H. Volwiler and R. M. Joyce have given us valuable encouragement and suggestions. Many other librarians, archivists, friends, and associates of Adams have furnished impor- tant documents and information. Some of the material in the pres- ent paper appeared in a publication by us entitled "The Role of Roger Adams in American Science," journal of Chemical Education, 56 (1979~:163.

16 BIOGRAPHICAL MEMOIRS B IBLIOGRAPHY 1910 With H. A. Torrey. Uber in alkalien unlosliche Phenole. Ber. Dtsch. Chem. Ges., 43: 3227-28. 1915 With C. L. Jackson. Hexabromodiacetyl. I. Am. Chem. Soc., 37: 2522-36. With L. Clarke. Normal nonane. I. Am. Chem. Soc., 37:2536-38 With H. Gilman. Phenyl esters of oxalic acid. }. Am. Chem. Soc. 37:271~20. 1916 With L. F. Weeks. Action of oxalyl chloride on primary, secondary and tertiary alcohols. }. Am. Chem. Soc., 38:251~19. With C. H. Beebe. Action of the Grignard reagent on CN com- pounds. Synthesis of amidines from cyanamides. J. Am. Chem. Soc., 38:2768-72. 1918 With W. V. Wirth and H. E. French. Oxalyl chloride as a reagent in organic chemistry. II. Preparation of aromatic acid anhy- drides; reaction with alcohols. I. Am. Chem. Soc., 40:424-31. With O. Kamm. Organic chemical reagents. I. Dimethylglyoxime. }. Am. Chem. Soc., 40:1281-89. With E. H. Vollweiler. The reaction between acid halides and alde- hydes. I. J. Am. Chem. Soc., 40: 1732-46. 1919 Alkali-insoluble phenols. I. Am. Chem. Soc., 41:247-70. With R. E. Rindfusz. Cyclic ethers from o-allyl phenols; methylene coumaranes. l. Am. Chem. Soc.' 41:648-65. With V. Voorhees. Organic chemical reagents. IV. The preparation of alkyl iodides. J. Am. Chem. Soc., 41:789-98. 1920 With C. S. Marvel. Organic chemical reagents. VI. Reagents from n-butyl alcohol. J. Am. Chem. Soc., 42:310-20.

ROGER ADAMS 17 With L. H. Ulich. The use of oxalyl chloride and bromide for producing acid chlorides, acid bromides or acid anhydrides. III. }. Am. Chem. Soc., 42:599-611. With S. G. Powell. A comparison of the activity of certain unsatu- rated groups with the activity of the allyl group in certain ethers. }. Am. Chem. Soc., 42:646-58. With H. B. Bramlet and F. H. Tendick. The action of the Grignard reagent on thiocyanates. l. Am. Chem. Soc., 42:2369-74. With C. S. Palmer. The reactions of the arsines. Preliminary paper. Condensation of primary arsines with aldehydes. I. Am. Chem. Soc., 42:2375-78. 1921 With H. E. French. The reaction between acid halides and alde- hydes. II. I. Am. Chem. Soc., 43:651-59. With L. H. Ulich. The reaction between acid halides and aldehydes. III. I. Am. Chem. Soc., 43:660-67. With I. R. Johnson. 2-Phenylquinoline-4-carboxylic acid-6-arsonic acid. I. Am. Chem. Soc., 43:2255-58. 1922 With A. }. Quick. Aliphatic arsenic and arsinic acids, and aliphatic- aromatic arsinic acids. I. Am. Chem. Soc., 44:805-16. With M. F. Fogler and C. W. Kreger. The structure of disalicyl aldehyde. }. Am. Chem. Soc., 44:1126-33. With C. S. Palmer. The reactions of the arsines. II. Condensation of aromatic primary arsines with aldehydes. I. Am. Chem. Soc., 44: 1356-82. With V. Voorhees. The use of the oxides of platinum for the cata- lytic reduction of organic compounds. I. l. Am. Chem. Soc., 44: 1397-405. With F. L. Roman and W. N. Sperry. The structure of the com- pounds produced from olefins and mercury salts: mercurated dihydrobenzofurans. I. Am. Chem. Soc., 44:1781-92. With W. D. Langley. The condensation of certain nitrites and vari- ous polyhydroxyphenols to form phenolic acids. I. Am. Chem. Soc., 44:2320-30. With A. W. Ingersoll. Optically active dyes. I. I. Am. Chem. Soc., 44:2930-37.

18 BIOGRAPHICAL MEMOIRS 1923 With }. E. Bullock and W. C. Wilson. Contribution to the structure of benzidine. I. Am. Chem. Soc., 45:521-27. With W. C. Wilson. Rings through the meta and para positions of benzene. A study of certain ethers of resorcinol and meta- aminophenol. }. Am. Chem. Soc., 45:528-40. With I. B. Segur. ,(3-Arylamino ethanols. {. Am. Chem. Soc., 45:785-90. With }. S. Pierce. Tetrahydro- 1,3,2-oxazones and substituted ~y-amino propanols. I. Am. Chem. Soc., 45:790-95. With W. H. Carothers. Platinum oxide as a catalyst in the reduction of organic compounds. II. Reduction of aldebydes. Activation of the catalyst by the salts of certain metals. }. Am. Chem. Soc., 45: 1071-86. With l. R. Johnson. Arsenated derivatives of phenyldiketopyrro- lidine. I. Am. Chem. Soc., 45: 1307- 15. With R. I. Kaufman. Production of imido thiol esters by the con- densation of thiocyanates with resorcinol or phloroglucinol. }. Am. Chem. Soc., 45: 1744-52. With L. E. Mills. Mercurated 1-methyl-1,2-dihydrobenzofurans. J. Am. Chem. Soc., 45:1842-54. With R. L. Shriner. Platinum oxide as a catalyst in the reduction of organic compounds. I I I. Preparation and properties of the oxide of platinum obtained by the fusion of chloroplatinic acid with sodium nitrate. }. Am. Chem. Soc., 45:2171-79. With I. Levine. Simplification of the Gatterman synthesis of hy- droxy aldehydes. I. Am. Chem. Soc., 45:2373-77. With A. W. Sloan and B. S. Taylor. Aryl 1,3-benzodioxanes (aryl methylene-saligenins). I. Am. Chem. Soc., 45:2417-20. With G. D. Graves. Trihydroxy-methyl-anthraquinones. I. I. Am. Chem. Soc., 45: 2439-55. With I. H. Gardner. Trihydroxy-methyl-anthraquinones. II. }. Am. Chem. Soc., 45: 2455-62. With C. G. Tomecko. The allyl ethers of various carbohydrates. I Am. Chem. Soc., 45:2698-701. With S. M. McElvain. Synthesis of a new bicyclic nitrogen ring. Isogranatanine derivatives. Preparation of an isomer of homo- cocaine. l. Am. Chem. Soc., 45:2738-50.

ROGER ADAMS 19 With W. E. Kaufmann. The use of platinum oxide as a catalyst in the reduction of organic compounds. IV. Reduction of furfural and its derivatives. I. Am. Chem. Soc., 45:3029-44 With C. W. Rodewald. Arsono-arylamino alcohols. I. Am. Chem. Soc., 45:3102-5. 1924 With R. A. Jacobson. Trihydroxy-methylanthraquinones. III. Syn- thesis of emodin. i. Am. Chem. Soc., 46:1312-16. With Edna Montgomery. Simplification of the Gatterman synthesis of aromatic aldehydes. II. I. Am. Chem. Soc., 46:1518-21. With W. H. Carothers. Platinum oxide as a catalyst in the reduction of organic compounds. V. The preparation of primary alcohols by the catalytic hydrogenation of aldehydes. J. Am. Chem. Soc., 46: 1675-83. With R. L. Shriner. The preparation of palladous oxide and its use as a catalyst in the reduction of organic compounds. VI. l. Am. Chem. Soc., 46:1683-93. With C. R. Noller. The use of aliphatic acid anhydrides in the preparation of ketones by the Friedel and Crafts reaction. I. Am. Chem. Soc., 46:1889-96. With W. W. Bauer. Diarsono-diphenyl and derivatives. I. Am. Chem. Soc., 46:1925-31. With W. R. Brode. Optically active dyes. II. Adsorption, absorption spectra and rotation. l. Am. Chem. Soc., 46:2032-43. With C. F. Rassweiler. The structure of dehydro-acetic acid. I Am. Chem. Soc., 46:2758-64. With I. A. Koten. Certain reactions of the alkyl and aryl mercuric hydroxides. I. Am. Chem. Soc., 46:2764-69. With R. A. Jacobson. Polyhydroxy-methylanthraquinones. IV. Condensation of opianic acid with substituted phenols. Orienta- tion in the preparation of anthraquinones. I. Am. Chem. Soc., 46:2788-93. 1925 With R. A. Jacobson. Trihydroxy-methylanthraquinones. V. Syn- thesis of morindone. I. Am. Chem. Soc., 47:283-90. With Katharine Ogden. Arsonophenyl-cinchoninic acid and de- rivatives. J. Am. Chem. Soc., 47:82~30.

20 BIOGRAPHICAL MEMOIRS With W. H. Carothers. Platinum oxide as a catalyst in the reduction of organic compounds. VII. A study of the effects of numerous substances on the platinum catalysis of the reduction of benzal- dehyde. }. Am. Chem. Soc., 47:1047-63. With l. S. Pierce. Platinum oxide as a catalyst in the reduction of organic compounds. VIII. The reduction of alkyl furyl car- binols. I. Am. Chem. Soc., 47: 1098-104. With l. W. Kern and R. L. Shriner. Platinum and palladium oxides as catalysts in the reduction of organic compounds. IX. The reduction of olefins. I. Am. Chem. Soc., 47:1147-58. With H. Heckel. Platinum oxide as a catalyst in the reduction of organic compounds. X. Reduction of aminophenols to cyclic amino-alcohols. l. Am. Chem. Soc., 47: 1712- 18. With R. A. Jacobson. Polyhydroxy and polyhydroxymethyl anthra- quinones. VI. Syntheses from opianic acid and phenols or cre- sols. }. Am. Chem. Soc., 47:2011- 18. With C. L. Butler, Jr. Search in the diphenylmethane series for the isomerism characteristic of certain diphenyl derivatives. I. Am. Chem. Soc., 47:2610-20. With R. L. Shriner. Structure of chaulmoogric and hydnocarpic acids. I. T. Am. Chem. Soc., 47:2727-39. With H. O. Calvery and C. R. Noller. Arsonophenyl-cinchoninic acid (arsono-cinchopen) and derivatives. II. }. Am. Chem. Soc., 47:3058-60. With W. F. Tuley. Reduction of cinnamic aldehyde to cinnamyl alcohol in the presence of platinum-oxide platinum black and promoters. XI. J. Am. Chem. Soc., 47:3061-68. 1926 With G. S. Hiers. Uber die Reduktion der o-Phenylen-essig- propionsaure und verschiedener aromatischer Amine mit Wasserstoff unter Verwendung von Platinoxyd-Platinschwarz als Katalysator. XII. Ber. Dtsch. Chem. Ges., 59:162-70. With B. S. Garvey. Selective reduction of citral by means of platinum-oxide platinum black and a promoter. XIII. }. Am. Chem. Soc., 48:477-82. With }. V. Supniewski. Organic bismuth compounds. I. Preparation of tricarboxy-triphenylbismuth dichlorides and certain nitro- triaryl bismuth compounds. I. Am. Chem. Soc., 48: 507- 17. With C. R. Noller. The preparation and use of aldehyde esters

ROGER ADAMS 21 formed by ozonation of the methyl esters of various unsaturated acids. I. Am. Chem. Soc., 48:1074-80. With C. R. Noller. Synthesis of dihydrochaulmoogric and dihydro- hydnocarpic acids. II. I. Am. Chem. Soc., 48:1080-89. With G. S. Hiers. The synthesis of homologs of dihydrochaulmoog- ric and dihydrohydnocarpic acids containing a cyclohexyl in place of a cyclopentyl group. III. J. Am. Chem. Soc., 48: 1089-93. With E. K. Rideal, W. B. Burnett, R. L. Jenkins, and E. E. Dreger. Chemical constitution, physiological action and physical proper- ties in a series of alky~para-aminobenzoates. I. Am. Chem. Soc., 48: 1758-70. With E. B. Vliet. The relationship between hydrogen-ion concen- tration and chemical constitution in certain local anesthetics. I. Am. Chem. Soc., 48:2158-62. With W. R. Brode. Optically active dyes. III. Physical properties, dyeing reactions and mechanism of dyeing. I. Am. Chem. Soc., 48:2193-201. With W. R. Brode. Optically active dyes. IV. Asymmetric dyes from meta-aminomandelic acid. I. Am. Chem. Soc., 48:2202-6. With G. S. Hiers. co-Cyclohexyl derivatives of various normal ali- phatic acids. IV. I. Am. Chem. Soc., 48:2385-93. With R. H. VanDyke. Synthesis of chaulmoogrylacetic acid. V. J. Am. Chem. Soc., 48:2393-95. With J. Sacks. The synthesis of homochaulmoogric acid, homohyd- nocarpic acid and chaulmoogrylamines. VI. I. Am. Chem. Soc., 48:2395-99. With C. R. Noller. Synthesis of a homolog of chaulmoogric acid. A2-Cyclopentenylacetic acid. VII. J. Am. Chem. Soc., 48: 2441- 18. 1927 With S. V. Puntambeker. Polyhydroxy-anthraquinones. VII. Struc- ture and synthesis of hydroxyanthrarufin and of rufiopin. }. Am. Chem. Soc., 49:48~91. With C. G. Tomecko. The synthesis of 9-, 10-, 11-, 12-, and 13-hydroxystearic acids. I. Am. Chem. Soc., 49:522-30. With F. L. Cohen and O. W. Rees. Reduction of aromatic nitro compounds to amines with hydrogen and platinum-oxide plati- num black as a catalyst. XIV. T. Am. Chem. Soc., 49:1093-99.

22 BIOGRAPHICAL MEMOIRS With G. S. Hiers. Catalytic reduction of di- and tri-phenylamines with hydrogen and platinum-oxide platinum black. XV. I. Am. Chem. Soc., 49: 1099-103. With H. Heckel. Cyclic alkamine esters of para-aminobenzoic acid. II. I. Am. Chem. Soc., 49, 1303-7. With O. A. Barnes. Piperidyl and substituted piperidyl alkyl para- aminobenzoates. III. I. Am. Chem. Soc., 49:1307-15. With R. H. Talbot. Alicyclic derivatives of resorcinol. I. Am. Chem. Soc., 49:2040-42. With Florence D. Stouder. Polyhydroxy-methylanthraquinones. IX. Contribution to the structure of rubiadin. I. Am. Chem. Soc., 49:2043-45. With R. H. Bray. Selective reduction of furfuracrolein by means of platinum-oxide platinum black and hydrogen. XVI. }. Am. Chem. Soc., 49:2101-6. With M. M. Brubaker. The structure of the condensation products of ortho-phthalaldehydic acids with phenols and phenol esters. VIII. I. Am. Chem. Soc., 49:2279-96. With W. M. Stanley, S. G. Ford, and W. R. Peterson. Various `~-cyclohexylalkyl alkyl acetic acids and their action toward B. Leprae. VIII. J. Am. Chem. Soc., 49:2934~40. With I. A. Arvin. Certain /~2-cyclopentenyl alkyl acetic acids and their action toward B. Leprae. IX. ]. Am. Chem. Soc., 49: 2940-42. 1928 With W. M. Stanley and H. A. Stearns. Cyclohexyl and cyclohexyl- methyl alkyl acetic acids and their action toward B. Leprae. X. ]. Am. Chem. Soc., 50:1475-78. With G. R. Yohe. Cyclopentyl alkyl acetic acids and c~cyclo- pentylethyl alkyl acetic acids and their bactericidal action toward B. Leprae. XI. J. Am. Chem. Soc., 50:1503-8. With Letha A. Davies. The structures of convolvulinolic and jalapinolic acids. Synthesis of 11-hydroxypentadecanoic and 11-hydroxyhexadecanoic acids. I. Am. Chem. Soc., 50: 1749-55. With I. A. Arvin. A2-Cyclopentenylethyl alkyl acetic acids and their bactericidal action toward B. Leprae. XII. I. Am. Chem. Soc., 50: 1790-94. With I. R. Marshall. The use of platinum-oxide platinum black in

ROGER ADAMS 23 the catalytic reduction of aromatic hydrocarbons. XVII. I. Am. Chem. Soc., 50:1970-73. With I. A. Arvin. Cyclopropylmethyl alkyl acetic acids and their bactericidal action toward B. Leprae. XIII. I. Am. Chem. Soc., 50:1983-85. With T. S. Hamilton. Reduction of pyridine hydrochloride and pyridonium salts by means of hydrogen and platinum-oxide platinum black. XVIII. I. Am. Chem. Soc., 50:2260-63. With I. F. Hyde and E. Browning. Synthetic homologs of d,1 -ephedrine. I. Am. Chem. Soc., 50:2287-92. With Letha A. Davies. Di-(cyclohexylalkyl) acetic acids. XIV. l. Am. Chem. Soc., 50:2297-98. With I. F. Hyde. Study of the possible isomerism of certain analogs of resolvable diphenyl compounds. I. Am. Chem. Soc., 50: 2499-506. 1929 With W. H. Lycan. ~Hydroxy aliphatic acids. Synthesis of sabinic acid. J. Am. Chem. Soc., 51 :625-29. With W. W. Moyer. Stereoisomerism of diphenyl compounds. Resolution of 3,3'-diaminodimesityl. II. I. Am. Chem. Soc., 51 :630-38. With W. M. Stanley. Stereochemistry of diphenyl compounds. The resolution of 2,2'-dihydroxy-3,3'-dicarboxy- 1,1 '-dinaphthyl. III. Rec. Trav. Chim. Pays-gas, 48:1035-40. With W. M. Stanley and Marian S. lay. The preparation of certain octadecanoic acids and their bactericidal action toward B. Leprae. XV.~. Am. Chem. Soc., 51:1261-66. With W. M. Stanley. The synthesis of chaulmoogric acid from hyd- nocarpic acid. I. Am. Chem. Soc., 51:1515-18. With W. H. Lycan. ~Hydroxy aliphatic acids. II. Conversion of c~hydroxydecanoic acid to chain poly-intermolecular esters and to a dimeric cyclic ester. I. Am. Chem. Soc., 51:3450-64. 1930 With E. W. Bousquet. Substituted phenylethylbarbituric acids. I. Am. Chem. Soc., 52:224-29. With W. M. Stanley. The stereoisomerism of diphenyl compounds. IV. I. Am. Chem. Soc., 52:120~1205.

24 BIOGRAPHICAL MEMOIRS With S. G. Ford. Cyclobutylalkyl alkyl acetic acids and their bacteri- cidal action toward B. Leprae. XVI. ]. Am. Chem. Soc., 52: 1259 61. With E. Browning and H. W. Woodrow. Preparation and bacterio- logical action toward B. Leprae of certain olefinic acids. XVII. I. Am. Chem. Soc., 52: 1281-83. With B. F. Armendt. Certain dialkyl acetic acids containing 12, 13, and 14 carbon atoms and their bactericidal action toward B. Leprae. XVIII. J. Am. Chem. Soc., 52:128~91. With L. H. Bock and W. W. Moyer. Stereochemistry of diphenyl compounds. V. Preparation and resolution of 2,4,6,2',4',6'- hexanitro-3,3'-dicarboxydiphenyl. J. Am. Chem. Soc., 52: 2054 60. With H. A. Stearns. Stereochemistry of diphenyl compounds. VI. Preparation and resolution of 2,4,6,2 ',4'-pentanitro-3-carboxy- diphenyl. J. Am. Chem. Soc., 52:2070~75. With C. M. Greer. Preparation and bactericidal properties of cer- tain pentadecanoic, heptadecanoic and nonadecanoic acids. XIX. I. Am. Chem. Soc., 52:2540~43. With R. W. Maxwell. Study of possible isomerism of certain analogs of resolvable diphenyl compounds. VII. J. Am. Chem. Soc., 52:2959~72. With E. Browning. Stereochemistry of diphenylbenzenes. Prep- aration of stereoisomeric 3,6-di-~2,4-dimethylphenyl)-2,5-di- bromohydroquinones and their derivatives. IX. I. Am. Chem. Soc., 52:409~107. With W. M. Stanley. The stereochemical study of diphenyl-2,2'- disulfonic acid. VIII. I. Am. Chem. Soc., 52:4471-76. With Catherine C. Steele. Stereochemistry of phenylpyridine compounds: the preparation and investigation of 2-~2-carboxy- 6-chlorophenyl)-pyridine-3-carboxylic acid and 3-~2-carboxy- phenyl)-6-phenylpyridine-2,4-dicarboxylic acid. X. J. Am. Chem. Soc., 52:452~35. With J. B. Hale and W. H. Lycan. Synthesis of nervonic acid. J. Am. Chem. Soc., 52:4536-39. With R. W. Stoughton. Stereochemistry of diphenyl compounds. The preparation and resolution of 2-methyl-6-nitro-2'-carboxy- diphenyl. XI. }. Am. Chem. Soc., 52:5263-67.

ROGER ADAMS 1931 25 With P. R. Shildneck. Stereochemistry of diphenylbenzenes. Meso and racemic 2,5-di-~3-bromo-2,4,6-trimethylphenyl)-3,6-dibro- mohydroquinones and the corresponding quinones. XII. I. Am. Chem. Soc., 53:343-52. With L. H. Bock. The stereochemistry of N-phenylpyrroles. The preparation and resolution of N-2-carboxyphenyl-2,5-di- methyl-3-carboxypyrrole. XIII. I. Am. Chem. Soc., 53:37~76. With E. C. Kleiderer. Stereochemistry of diphenyl compounds. The preparation and resolution of 3,5,3',5',-tetra-methyl- 2,2'-difluoro-6,6'-diaminodiphenyl. XIV. }. Am. Chem. Soc., 53: 1575-80. With P. R. Shildneck. Stereochemistry of diphenylbenzenes. The cis and bans forms of 2,5-di-~3-bromo-2,4,6-trimethyl-phenyl)- 1,3, 4,6-tetrahydroxybenzenes and the corresponding acylates. XV. I. Am. Chem. Soc., 53:2203-14. With Chin Chang. Stereochemistry of N,N'-dipyrryls. Resolution of N,N',2,5,2',5'-tetramethyl-3,3'-dicarboxy-dipyrryl. XVI. J. Am. Chem. Soc., 53:2353-57. With W. M. Stanley. Stereochemistry of diphenyls. Preparation and properties of 4,4'-dicarboxy- 1,1'-dianthraquinoyl. XVII. J. Am. Chem. Soc., 53:2364-68. With P. R. Shildneck. The synthesis of polyporic acid and atromen- tin dimethyl ether. I. Am. Chem. Soc., 53:2373-79. With D. W. Hill. Stereochemistry of phenylquinones. The prepara- tion and resolution of 2-~3-bromo-2,4,6-trimethylphenyl)-5- methylbenzoquinone-3,6-di-(acetic acid). XVIII. I. Am. Chem. Soc., 53:3453-61. With L. I. Roll. The structure of enol-acetates and the correspond- ing vinyl-amines. }. Am. Chem. Soc., 53:3469-76. With L. H. Bock. Stereochemistry of phenyl pyrroles. XIX. I. Am. Chem. Soc., 53:3519-22. 1932 With W. M. Stanley. The surface tension of various aliphatic acids previously studied for bactericidal action toMycobacterium leprae. XX. J. Am. Chem. Soc., 54:1548-57.

26 BIOGRAPHICAL MEMOIRS With E. H. Woodruff. Stereochemistry of dipyridyls. Preparation and resolution of 2,4,2',4',-tetracarboxy-6,6'-diphenyl-3,3'- dipyridyl. XX. J. Am. Chem. Soc., 54:1977-82. With Julius White. Stereochemistry of diphenyls. XXI. Resolution of 2,4,6,2',4',6'-hexachloro-3,3'-dicarboxydiphenyl. I. Am. Chem. Soc., 54:210~8. With W. M. Stanley, G. H. Coleman, C. M. Greer, and I. Sacks. Bacteriological action of certain synthetic organic acids toward Mycobacterium leprae and other acid-fast bacteria. XXI. }. Pharmacol. Exp. Ther., 45: 121-62. With L. l. Roll. The stereochemistry of carbodiimides. XXII. I. Am. Chem. Soc., 54:2494-98. With H. C. Yuan. Stereochemistry of diphenyl. XXIII. Opti- cally active 2,5-dimethoxy-2'-nitro-6'-carboxydiphenyl and the mutarotation of its salts. I. Am. Chem. Soc., 54:296~73. With B. C. Becker. Stereochemistry of diphenyls. XXIV. Prepara- tion and properties of 2,2'-difluoro-3,3'-dicarboxy-6,6'-di- methoxydiphenyl. J. Am. Chem. Soc., 54:2973-82. With E. H. Johnson and V. Weinmayr. Substitution products of alpha-naphthoyl-ortho-benzoic acid. J. Am. Chem. Soc., 54: 3289-95. With R. W. Stoughton. Stereochemistry of diphenyls. XXV. The relative interfering effects of the groups F. OCH3, C1, Br as determined by the relative rates of racemization of the 2'-substituted 2-nitro-6-carboxydiphenyls. I. Am. Chem. Soc., 54:4426-34. With H. C. Yuan. Stereochemistry of diphenyls. XXVI. The effect of substitution on the rate of racemization of certain optically active diphenyls. l. Am. Chem. Soc., 54:443~43. 1933 With W. M. Stanley and Edward McMahon. Stereochemistry of diphenyls. XXVII. Comparison of the racemization of 2,2'-difluoro-6,6'-dicarboxydiphenyl and 2,2'-di~nethoxy-6,6'- dicarboxydiphenyl. I. Am. Chem. Soc., 55:706-16. With E. C. Kleiderer. Stereochemistry of diphenyl. XXVIII. Prep- aration and properties of 2,2'-difluoro-3,3'-dicarboxy-5,5'- dimethyl-6,6'-dinitrodiphenyl. l. Am. Chem. Soc., 55:716- 19.

ROGER ADAMS 27 With W. I. Patterson. Stereochemistry of N-phenylpyrroles. XXIX. Preparation and properties of o-N-carbazyl- and o-N-(3- nitrocarbazyl)-benzoic acid. I. Am. Chem. Soc., 55: 1069-72. With N. E. Searle. Stereochemistry of diphenyls. XXX. Preparation and resolution of 2,2'-diiodo-4,4'-dicarboxydiphenyl. }. Am. Chem. Soc., 55:1649-54. With H. C. Yuan. The stereochemistry of diphenyls and analogous compounds. Chem. Rev., 12:261-338. With E. C. Kleiderer. Stereochemistry of diphenyls. XXXI. Prepa- ration and properties of 2,2'-,6,6'-tetrafluoro-3,3'-dicarboxy- 5?5'-dichlorodiphenyl. I. Am. Chem. Soc., 55:4219-25. With A. M. VanArendonk and M. E. Cupery. Stereochemistry of diphenyls. XXXII. Preparation and properties of certain 2,2'-, 6,6'-tetramethoxydiphenyls. I. Am. Chem. Soc., 55:4225-30. With A. M. VanArendonk and B. C. Becker. Stereochemistry of diphenyls. XXXIII. Preparation and properties of 2,3'-dinitro- 6-carboxy-2',6'-dimethoxydiphenyl and 2-nitro-6-carboxy-2'- fluoro-6'-methoxydiphenyl. I. Am. Chem. Soc., 55:423(~34. With Marion E. Maclean. Diastereoisomers of 2,5-diphenylsulfinyl- hydroquinone diacetate. i. Am. Chem. Soc., 55:4681-83. With Marion E. Maclean. Study of certain analogs of resolvable diphenyls. I. Am. Chem. Soc., 55:468~88. With A. E. Knauf. Stereochemistry of diphenyls. XXXIV. Prepara- tion and properties of 2,2',4,4',5,5',6,6'-octamethyldiphenyl- 3,3'-disulfonic acid and diphenyl-3,3'-disulfonic acid. J. Am. Chem. Soc., 55:470~9. 1934 With S. L. Chien. Stereochemistry of diphenyls. XXXV. The effect of 3'-substituents on the rate of racemization of 2-nitro-6- carboxy-2'-methoxydiphenyl. I. Am. Chem. Soc., 56:1787-92. With Chin Chang. Stereochemistry of diphenyls. XXXVI. Prepara- tion and resolution of certain substituted dipyrrylbenzenes. I. Am. Chem. Soc., 56:208~92. With D. F. Holmes. The use of l-menthoxyacetyl chloride for the resolution of amino acids. I. Am. Chem. Soc., 56:2093-94. With A. E. Knauf and P. R. Shildneck. Stereochemistry of diphenyls. XXXVII. The resolution of certain substituted diphenyl-benzenes. I. Am. Chem. Soc., 56:210~11.

28 BIOGRAPHICAL MEMOIRS With N. E. Searle. Stereochemistry of diphenyls. XXXVIII. Resolu- tion of 2,2'-dibromo-4,4'-dicarboxydiphenyl. I. Am. Chem. Soc., 56:2112-14. With W. E. Hanford and Poe Liang. The constitution of vasicine. l. Am. Chem. Soc., 56:278(}83. 1935 With Q. R. Bartz and R. F. Miller. The introduction of isobutyl groups into phenols, cresols and homologous compounds. J. Am. Chem. Soc., 57:371-76. With W. I. Patterson. Stereochemistry of diphenyls. XXXIX. Syn- thesis of active 2,6-dibromo-3,3'-diamino-4,4'-ditolyl. J. Am. Chem. Soc., 57:762-64. With W. E. Hanford. The structure of vasicine. II. Synthesis ot desoxyvasicine. I. Am. Chem. Soc., 57:921-24. With R. C. Morris and W. E. Hanford. The structure of vasicine. III. Position of the hydroxyl group. J. Am. Chem. Soc., 57:951-54. With C. C. Li. Stereochemistry of diphenyls. XL. The effect of temperature and solvent on the rate of racemization of 2-nitro-6-carboxy-2'-alkoxydiphenyls. J. Am. Chem. Soc., 57: 1565-69. With W. E. Hanford. Stereochemistry of diphenyls. XLI. The ef- fect of 4'-substitution on the rate of racemization of 2-nitro-6-carboxy-2'-methoxydiphenyl. J. Am. Chem. Soc.. 57: 1592-95. With E. E. Gruber. Synthesis of certain hydrogenated phenan- threnes. J. Am. Chem. Soc., 57:2555-56. 1936 With C. Y. Hsing. Relative rates of racemization of substituted diamides of 2,2'-dimethoxy-6,6'-dicarboxydiphenyl. XLII. J. Am. Chem. Soc., 58:587-89. With R. F. Miller. Contribution to the multiplanar isomerism of cyclohexanes. I. Am. Chem. Soc., 58:787-91. With A. McLean. Succinic O!~d2,CY'~d2 acid and its derivatives. l. Am. Chem. Soc., 58:80~ 10. With M. T. Leffler. Succinic-`x~,cx-'~ acid and its derivatives. II Stereochemistry of the type RR'CHD. J. Am. Chem. Soc. 58:1551-55.

ROGER ADAMS 29 With M. T. Leffler. Stereochemistry of deuterium compounds of the type RR'CHD: camphane-2,3~2. I. Am. Chem. Soc., 58: 1555-58. 1937 With C. R. Kinney. Dideuteriovaline and dideuterioleucine. I. Am. Chem. Soc., 59:897-98. With F. C. McGrew. Stereochemistry of deuterium compounds of the type RR'CXHXD: Ethyl~4-ethylcarbinol. J. Am. Chem. Soc., 59: 1497-1500. With K. N. Campbell and R. C. Morris. The structure of gossypol. I. I. Am. Chem. Soc., 59: 172~28. With R. F. Miller and D. }. Butterbaugh. Structure of gossypol. II. Acylation. I. Am. Chem. Soc., 59:1729-31. With R. C. Morris. The structure of gossypol. III. Gossypol ethers. I. Am. Chem. Soc., 59:1731-35. With R. F. Miller. Structure of gossypol. IV. Anhydrogossypol and its derivatives. }. Am. Chem. Soc., 59:1736-38. With W. B. Burnett, R. L. Jenkins, C. H. Feet, and E. E. Dreger. Dialkylamino-alkanol esters of p-aminobenzoic acid. I. Am. Chem. Soc., 59:2248-52. With M. T. Leffler. Aminophenyl-2-oxazolines as local anesthetics. I. Am. Chem. Soc., 59:2252-58. With A. Novelli. Aminophenyl-2-pentoxazolines. J. Am. Chem. Soc., 59:2259-60. With S. H. Babcock. Aminophenyl thiazolines and thiazines. }. Am. Chem. Soc., 59:2260-61. With B. S. Friedman and Meredith Sparks. Aminophenyl oxazoles and thiazoles. l. Am. Chem. Soc., 59:2262-64. With Allene Jeanes. The addition of alkali metals to phenanthrene. I. Am. Chem. Soc., 59:2608-22. 1938 With D. S. Tarbell. The attempted resolution of phenyl~5- phenylaminomethane. l. Am. Chem. Soc., 60:1260-62. With H. R. Snyder. Stereochemistry of biphenyls. XLIII. The ef- fect of substitutents in the 4-position of 2-nitro-6-carboxy-2'- methoxybiphenyl. I. Am. Chem. Soc., 60:1411-15. With R. M. Joyce, tr. Stereochemistry of biphenyls. XLIV. Aleso and

30 BIOGRAPHICAL MEMOIRS racemic isophthalamides of 3-nitro-3'-aminobimesityl. J. Am. Chem. Soc., 60:1489-90. With R. M.Joyce,Jr. Stereochemistry of biphenyls. XLV. Stereoiso- meric dipyrryl biphenyls.J. Am. Chem. Soc., 60:1491-92. With C. C. Price and W. R. Dial. Structure of gossypol. V. Anilino derivatives. J. Am. Chem. Soc., 60:2158-60. With B. S. Friedman, C. C. Price, R. C. Morris, and E. C. Kirk- patrick. Structure of gossypol. VI. Addition products with buta- dienes. }. Am. Chem. Soc., 60:2160~2. With T. A. Geissman. Structure of gossypol. VII. Gossypol di- methyl ether. J. Am. Chem. Soc., 60:2163-66. With T. A. Geissman. Structure of gossypol. VIII. Derivatives of the ethers of gossypol. J. Am. Chem. Soc., 60:2166-70. With R. C. Morris and E. C. Kirkpatrick. Structure of gossypol. IX. Oxidation and degradation of gossypol hexamethyl ether; gos- sic acid. J. Am. Chem. Soc., 60:2170-74. With D. J. Butterbaugh. Structure of gossypol. X. Apogossypol and its degradation products. J. Am. Chem. Soc., 60:217~80. With E. C. Kirkpatrick. Structure of gossypol. XI. Absorption spec- tra of gossypol, its derivatives and of certain dinaphthalene compounds. J. Am. Chem. Soc., 60:2180-84. With T. A. Geissman. The structure of gossypol. XII. Gossylic acid lactone tetramethyl ether. J. Am. Chem. Soc., 60:218~88. With R. C. Morris. Structure of gossypol. XIII. Conversion of gossic acid to apogossypolic acid. J. Am. Chem. Soc., 60:2188-90. With R. C. Morris, D. J. Butterbaugh, and E. C. Kirkpatrick. Struc- ture of gossypol. XIV. Apogossypolic acid. J. Am. Chem. Soc. 60:2191-93. With R. C. Morris, T. A. Geissman, D. J. Butterbaugh, and E. C. Kirkpatrick. Structure of gossypol. XV. An interpretation of its reactions. I. Am. Chem. Soc., 60:2193-204. With E. E. Gruber. Lactone formation in the addition product of maleic anhydride and bicyclohexenyl. J. Am. Chem. Soc., 60: 2792-94. With T. A. Geissman and R. C. Morris. Structure of gossypol. XVI. Reduction products of gossypolone tetramethyl ether and gos- sypolonic acid tetramethyl ether. J. Am. Chem. Soc., 60: 2967-70. With T. A. Geissman and R. C. Morris. Structure of gossypol. XVII.

ROGER ADAMS 31 Nitration products of gossypol hexamethyl ether, gossypolone tetramethyl ether and gossypolonic acid tetramethyl ether. I. Am. Chem. Soc., 60:2970-72. With Madison Hunt and R. C. Morris. Structure of gossypol XVIII. Synthesis of 1,2-dimethoxy-3-isopropyl-5-aminoben zene, a degradation product of gossypol. J. Am. Chem. Soc. 60:2972-74. 1939 With Madison Hunt. Structure of gossypol. XIX. Synthesis of 1,2-dihydroxy-3-isopropyl-6-benzoic acid. I. Am. Chem. Soc. 61:1132-33. With Madison Hunt and B. R. Baker. Structure of gossypol. XX. Synthesis of 1,2-dihydroxy-3-isopropyl-5-benzoic acid. I. Am. Chem. Soc., 61:1134-37. With B. R. Baker. Structure of gossypol. XXI. Synthesis of 1,2-dimethoxy-3-isopropyl-4-benzoic acid and of apogossypolic acid. I. Am. Chem. Soc., 61:1138-42. With W. R. Dial. Structure of gossypol. XXII. Gossypol ethers and their reduction products. I. Am. Chem. Soc., 61:2077-82. With T. A. Geissman. Structure of gossypol. XXIII. Attempts to prepare desapogossypolone tetramethyl ether. Condensation of hexadiene-2,4 with dibenzoylethylene. l. Am. Chem. Soc., 61 :2083-89. With T. L. Cairns. Stereochemistry of biphenyls. XLVI. 2-Substi- tuted biphenyls. J. Am. Chem. Soc., 61:2179-81. With G. C. Finger. Stereochemistry of biphenyls. XLVII. Certain 3,6-di-~2,4-dimethylphenyl)-hydroquinones and their deriva- tives. }. Am. Chem. Soc., 61:2182-83. With P. H. Long and A. I. Johanson. Sulfanilamide derivatives. I. Am. Chem. Soc., 61: 2342-46. With P. H. Long and Allene Jeanes. Sulfanilamide derivatives. II. I. Am. Chem. Soc., 61:2346-49. With T. L. Cairns. Attempts to prepare optically active ethylenei- mine derivatives containing an asymmetric nitrogen atom. }. Am. Chem. Soc., 61:2464-67. With E. F. Rogers. The structure of monocrotaline, the alkaloid in Crotalaria spectabilis and Crotalaria retusa. I. ]. Am. Chem. Soc., 61:2815-19.

32 BIOGRAPHICAL MEMOIRS With E. F. Rogers and F. I. Sprules. Structure of monocrotaline. II. Monocrotic acid obtained by alkaline hydrolysis of the alkaloid. I. Am. Chem. Soc., 61:2819-21. With E. F. Rogers and R. S. Long. The structure of monocrotaline. III. Monocrotalic acid. }. Am. Chem. Soc., 61:2822-24. With J. B. Hale. Stereochemistry of biphenyls. XLVIII. A compari- son of the racemization rates of three isomeric 2,2',6-nitro-, carboxy-, methyl-biphenyls. J. Am. Chem. Soc., 61:2825-28. With G. C. Finger. Stereochemistry of biphenyls. XLIX. Compari- son of the racemization rates of the 2,2',6-nitro-, carboxy-, and methoxy-biphenyls. I. Am. Chem. Soc., 61:2828-30. 1 940 With M. W. Miller. Restricted rotation in aryl olefins. I. Preparation and resolution of ,8-chloro-,B-~2,4,6-trimethyl-3-bromophenyl)- c~-methylacrylic acid. I. Am. Chem. Soc., 62:53-56. With Marvin H. Gold. The synthesis of 1,3-diphenyldihydroiso- benzofurans, 1,3-diphenylisobenzofurans and o-dibenzoylben- zenes from the diene addition products to dibenzoylethylene. }. Am. Chem. Soc., 62:56-61. With Madison Hunt and }. H. Clark. Structure of cannabidiol, a product isolated from the marihuana extract of Minnesota wild hemp. I. J. Am. Chem. Soc., 62:196-200. With C. K. Cain and Hans Wolff. Structure of cannabidiol. II. Absorption spectra compared with those of various dihydric phenols. i. Am. Chem. Soc., 62:732-34. With Madison Hunt and }. H. Clark. Structure of cannabidiol. III. Reduction and cleavage. I. Am. Chem. Soc., 62:735-37. With R. B. Wearn. Diene addition products to diaroylethylenes and their transformation products. II. J. Am. Chem. Soc., 62: 1233-37. With Hans Wolff, C. K. Cain, and I. H. Clark. Structure of canna- bidiol. IV. The position of the linkage between the two rings. J. Am. Chem. Soc., 62:1770-75. With M. H. Gold. Absorption and fluorescence spectra of certain dihydroisobenzofurans and isobenzofurans. }. Am. Chem. Soc., 62:2038-42. With H. M. Teeter. Stereochemistry of biphenyls. L. Comparison of the interference of a methoxyl and an hydroxyl group. J. Am. Chem. Soc., 62:2188-90.

ROGER ADAMS 33 With L. I. Dankert. Restricted rotation in arylamines. I. Prepara- tion and resolution of N-succinyl-N-methylbromomesidine. I. Am. Chem. Soc., 62:2191-93. With D. C. Pease and J. H. Clark. Isolation of cannabinol, can- nabidiol and quebrachitol from red oil of Minnesota wild hemp. I. Am. Chem. Soc., 62:219~96. With D. C. Pease, I. H. Clark, and B. R. Baker. Structure of canna- binol. I. Preparation of an isomer, 3-hydroxy-1-n-amyl-6,6,9- trimethyl-6-dibenzopyran. I. Am. Chem. Soc., 62:2197-200. With C. K. Cain and B. R. Baker. Structure of cannabinol. II. Synthesis of two new isomers, 3-hydroxy-4-n-amyl and 3-hy- droxy-2-n-amyl-6,6,9-trimethyl-6-dibenzopyrans. I. Am. Chem. Soc., 62:2201-4. With B. R. Baker and R. B. Wearn. Structure of cannabinol. III. Synthesis of cannabinol, 1-hydroxy-3-n-amyl-6,6,9-trimethyl-6- dibenzopyran. J. Am. Chem. Soc., 62:2204-7. With B. R. Baker. Structure of cannabinol. IV. Synthesis of two additional isomers containing a resorcinol residue. I. Am. Chem. Soc., 62:2208-15. With Hans Wolff, C. K. Cain, and I. H. Clark. Structure of canna- bidiol. V. Position of the alicyclic double bonds. l. Am. Chem. Soc., 62:2215-19. With D. C. Pease, C. K. Cain, B. R. Baker, I. H. Clark, Hans Wolff, and R. B. Wearn. Conversion of cannabidiol to a product with marihuana activity. A type reaction for synthesis of analogous substances. Conversion of cannabidiol to cannabinol. I. Am. Chem. Soc., 62:2245-46. With R. S. Long. Structure of monocrotaline. IV. Monocrotalic acid. I. Am. Chem. Soc., 62:2289-94. With B. R. Baker. Structure of cannabinol. V. A second method of synthesis of cannabinol. I. Am. Chem. Soc., 62:2401. With D. C. Pease, C. K. Cain, and J. H. Clark. Structure of canna- bidiol. VI. Isomerization of cannabidiol to tetrahydrocanna- binol, a physiologically active product. Conversion of can- nabidiol to cannabinol. I. Am. Chem. Soc., 62:2402-5. With B. R. Baker. Structure of cannabidiol. VII. A method of synthesis of a tetrahydrocannabinol which possesses marihuana activity. I. Am. Chem. Soc., 62:2405-8. With S. Loewe, D. C. Pease, C. K. Cain, R. B. Wearn, B. R. Baker, and Hans Wolff. Structure of cannabidiol. VIII. Position of the

34 BIOGRAPHICAL MEMOIRS double bonds in cannabidiol. Maribuana activity of tetrahydro- cannabinols. I. Am. Chem. Soc., 62:2566-67. 1941 With N. Kornblum. Stereochemistry of biphenyls. LI. Resolution of diphenic acids having many-membered bridges across the 5,5'-positions: a novel type of restricted rotation. I. Am. Chem. Soc., 63: 188-200. With E. F. Rogers. Structure of monocrotaline. V. Retronecine, a derivative of 1-methylpyrrolizidine. I. Am. Chem. Soc., 63: 228-36. With T. A. Geissman, B. R. Baker, and H. M. Teeter. Structure of gossypol. XXIV. Attempts to prepare desapogossypolone tetra- methyl ether. }. Am. Chem. Soc., 63:528-34. With B. R. Baker. Structure of gossypol. XXV. Synthesis of desapo- gossylpolone tetramethyl ether. }. Am. Chem. Soc., 63:535-37. With E. F. Rogers. Structure of monocrotaline. VI. The structure of retronecine, platynecine and retronecanol. I. Am. Chem. Soc., 63:537-41. With D. E. gurney. The reactions of 2,8-dihydroxynaphthal- dehyde. }. Am. Chem. Soc., 63:1103-7. With A. W. Anderson and M. W. Miller. Restricted rotation in aryl olefins. II. Preparation and resolution of certain ,l3-chloro-,l3-~2,4,6-trimethyl- and 2,4,6-triethyl-3-bromophenyl)- acrylic acids. }. Am. Chem. Soc., 63: 1589-93. With S. Loewe, Charles Jelinek, and Hans Wolff. Tetrahydrocan- nabinol homologs with marihuana activity. IX. I. Am. Chem. Soc., 63:1971-73. With C. M. Smith and S. Loewe. Tetrahydrocannabinol homologs and analogs with marihuana activity. X. }. Am. Chem. Soc., 63: 1973-76. With C. K. Cain and S. Loewe. Tetrabydrocannabinol analogs with marihuana activity. XI. J. Am. Chem. Soc., 63: 1977-78. With L. N. Whitehill. Many-membered ring compounds by direct synthesis from two co,co'-bifunctional molecules. I. Am. Chem. Soc., 63:2073-78. With C. K. Cain, W. D. McPhee, and R. B. Wearn. Structure of cannabidiol. XII. Isomerization to tetrahydrocannabinols. Am. Chem. Soc., 63:2209-13.

ROGER ADAMS 35 With T. A. Geissman, W. R. Dial, and I. T. Fitzpatrick. Structure of gossypol. XXVI. Gossypolic acid. I. Am. Chem. Soc., 63:2439-41. With L. O. Binder. Restricted rotation in aryl olefins. III. Prepara- tion and resolution of ,8-chloro-,l3-~2-methyl-1-naphthyl)-acrylic acids. l. Am. Chem. Soc., 63:2773-76. With H. W. Stewart. Restricted rotation in arylamines. II. Prepara- tion and resolution of N-succinyl-N-ethyl-3-bromomesidine and 5-alkoxy-4-N-succinyl-4-alkylamino- 1,3-dimethylbenzenes. l. Am. Chem. Soc., 63:2859-64. 1942 Marihuana. In: Harvey Lectures, 37: 168-97. With M. Carmack and E. F. Rogers. The alkaloid of Crotalaria grantiana. I. Grantianine. l. Am. Chem. Soc., 64:571-73. With S. Loewe, C. M. Smith, and W. D. McPhee. Tetrahydrocanna- binol homologs and analogs with marihuana activity. XIII. I. Am. Chem. Soc., 64:69~97. With A. A. Albert. Restricted rotation in aryl amines. III. Prepara- tion and resolution of N-succinyl- 1-methylamino-2-methyl- naphthalene and N-succinyl- 1-methylamino-4-chloro-2-methyl- naphthalene. .} Am. Chem. Soc., 64: 1475-78. With W. I. Gross. Restricted rotation in aryl olefins. IV. Preparation and resolution of ~B-chloro-'S-~2-methoxy-4,6-dimethyl-5-chlo- rophenyl)~-methylacrylic and the corresponding acrylic acid. J. Am. Chem. Soc., 64:1786-90. With L. O. Binder and F. C. McGrew. Restricted rotation in aryl olefins. V. ~B-Bromo-,8-~2-alkoxynaphthyl)~-alkylacrylic acids. I. Am. Chem. Soc., 64:1791-94. With M. W. Miller, F. C. McGrew, and A. W. Anderson. Restricted rotation in aryl Cleans. VI. Substituted ,8-~2,7-dimethoxy-1- naphthyl)-c~-methylacrylic acids. I. Am. Chem. Soc., 64: 1795-801. With C. M. Smith and S. Loewe. Optically active synthetic tetrahy- drocannabinols; d- and 1-1-hydroxy-3-n-amyl-6,9,9-trimethyl- 7,8,9,10-tetrahydro-6-dibenzopyrans. XIV. I. Am. Chem. Soc., 64:2087-89. With J. E. Mahan. Basicity studies of tertiary vinyl amines. J. Am. Chem. Soc., 64:2588-93.

36 BIOGRAPHICAL MEMOIRS With Marvin Carmack and l. E. Mahan. Structure of monocro- taline. VII. Structure of retronecine and related bases. I. Am. Chem. Soc., 64:2593-97. With K. E. Hamlin, Jr. Structure of monocrotaline. VIII. The proof of primary and secondary hydroxyl groups in retronecine. J. Am. Chem. Soc., 64:2597-99. With S. Loewe, C. W. Theobald, and C. M. Smith. Tetrahydrocan- nabinol analogs with marihuana activity. XV. }. Am. Chem. Soc., 64:2653-55. With K. E. Hamlin, Jr., C. F. Jelinek, and R. F. Phillips. The struc- ture of riddelliine, the alkaloid in Senecio r~ddellii. I. ]. Am. Chem. Soc., 64:2760-63. 1943 With W. D. McPhee, R. B. Carlin, and Z. W. Wicks. The addition of dienes to coumarin and to certain substituted cinnamic acids. I. l. Am. Chem. Soc., 65:356-60. With R. B. Carlin. The addition of dienes to certain di-o-methoxy- substituted cinnamic acids. II. I. Am. Chem. Soc., 65:360-63. With J. E. Mahan. Structure of monocrotaline. IX. Proof of the position of the double bond in retronecine. I. Am. Chem. Soc., 65:2009-12. With I. M. Wilkinson, Jr. Structure of monocrotaline. X. Monocro- talic acid. I. Am. Chem. Soc., 65:2203-8. With C. W. Theobald. Restriction rotation in aryl olefins. VII. A new synthesis of hindered ,8-substituted-~3-arylacrylic acids. J. Am. Chem. Soc., 65:2208-12. With C. W. Theobald. Restricted rotation in aryl olef~ns. VIII. The synthesis and resolution of certain ,l3-substituted-,(~-arylacrylic acids. I. Am. Chem. Soc., 65:2383-87. 1944 With }. H. Clark, Nathan Kornblum, and Hans Wolff. Substituted aminobenzofuroquinolines. I. Am. Chem. Soc., 66:22-26. With N. I. Leonard. Structure of monocrotaline. XI. Proof of the structure of retronecine. }. Am. Chem. Soc., 66:257-63. With J. W. Mecorney. The formation of a chromone by the von Pechmann condensation of ethyl acetoacetate with 4-chloro- 3,5-dimethylphenol. I. Am. Chem. Soc., 66:802-5.

ROGER ADAMS 37 With Z. W. Wicks. 2,3,5,8-Tetramethoxy-6,7-dimethyl- 1-naph- thaldehyde. I. Am. Chem. Soc., 66: 1315-16. 1945 With S. I. Cristol, A. W. Anderson, and A. A. Albert. The structure of leucenol. I. }. Am. Chem. Soc., 67:89-92. With R. S. Ludington. Restricted rotation in aryl olefins. IX. Effect of various substituents on the olefin grouping. I Am. Chem. Soc., 67:794-97. With i. W. Mecorney. Restricted rotation in aryl olefins. X. ,8-methyl-,3-arylacrylic acids. l. Am. Chem. Soc., 67:798-802. With K. H. Chen and S. Loewe. Tetrahydrocannabinol homologs with a s-alkyl group in the 3-position. XVI. I. Am. Chem. Soc., 67: 1534-37. 1947 With V. V. Jones. The structure of leucenol. II. l. Am. Chem. Soc., 69: 1803-5. With T. R. Govindachari. The structure of leucenol. III. Synthesis of 2,5-dihydroxypyridine (5-hydroxy-2-pyridone). }. Am. Chem. Soc., 69:1806-8. With V. V. Jones and }. L. Johnson. The structure of leucenol. IV. J Am. Chem. Soc., 69:1810-12. 1948 With B. F. Aycock, Jr. and S. Loewe. Tetrahydrocannabinol homo- logs. XVII. I. Am. Chem. Soc., 70:662-64. With S. MacKenzie, Jr. and S. Loewe. Tetrahydrocannabinol homologs with doubly branched alkyl groups in the 3-position. XVIII. }. Am. Chem. Soc., 70:664-68. With Jean Mathieu. A new synthesis of atranol (2,6-dihydroxy-4- methylbenzaldehyde) and the corresponding cinnamic acid. }. Am. Chem. Soc., 70:2120-22. With N. K. Sundholm. Restricted rotation in aryl amines. IV. Prep- aration and resolution of N-succinyl- 1-methylamino-2,4-di- methyl-6-substituted benzenes. }. Am. Chem. Soc., 70:2667-73. With R. G. Chase. Restricted rotation in substituted aromatic amines. V. Derivatives of N,N'-dimethyldiaminomesitylene. I. Am. Chem. Soc., 70:4202-4.

38 BIOGRAPHICAL MEMOIRS With l. I. Tjepkema. Restricted rotation in substituted aromatic amines. VI. Stereoisomers of N,N'-dialkyl-N,N'-dibenzenesul- fonyl-diaminomesitylene. l. Am. Chem. Soc., 70:420~13. 1949 Restricted rotation. Rec. Chem. Frog., 10:91-99. With }. Hine and }. Campbell. Triarylpyridylmethanes. I. Am. Chem. Soc., 71:387-90. With R. D. Lipscomb. Amine bisulfite addition products of alde- hydes and ketones. I. I. Am. Chem. Soc., 71:519-22. With I. D. Garber. Amine bisulfites. II. Their use as resolving agents for aldehydes and ketones. }. Am. Chem. Soc., 71:522-26. With l. L. Johnson. Leucenol. VI. A total synthesis. I. Am. Chem. Soc., 71: 705-8. With T. R. Govindachari. Senecio alkaloids: cat- and ,l3-longilobine from Senecio longilobus. J. Am. Chem. Soc., 71: 118~86. With A. W. Schrecker. Condensation reactions of N-substituted pyridones. J. Am. Chem. Soc., 71:118~95. With M. Rothstein. Restricted rotation in substituted aromatic amines. VII. Stereoisomers of N,N'-dimethyl-N,N'-diarylsul- fonyldiamino mesitylenes. I. Am. Chem. Soc., 71:162() 23. With M. Harfenist and S. Loewe. New analogs of tetrahydrocanna- binol. XIX. I. Am. Chem. Soc., 71:1624-28. With T. R. Govindachari. Senecio alkaloids: the isolation of senecio- nine from Senecio cineraria and some observations on the struc- ture of senecionine. I. Am. Chem. Soc., 71: 1953-56. With T. R. Govindachari. Senecio alkaloids: the alkaloids of Senecio douglasii, carthamoides, eremophilus, ampullaceus and parksii. ]. Am. Chem. Soc., 71: 195~60. With W. Herz. Helenalin. I. Isolation and properties. J. Am. Chem. Soc., 71:254~51. With W. Herz. Helenalin. II. Helenalin oxide. I. Am. Chem. Soc., 71:2551-54. With W. Herz. Helenalin. III. Reduction and dehydrogenation. J. Am. Chem. Soc., 71:2554-59. With I. B. Campbell. 2-Triphenylmethylaminopyridine. J. Am. Chem. Soc., 71:3539-42. With V. V. Jones. Addition and condensation reactions of 2-py- ridone. l. Am. Chem. Soc., 71:382~33.

ROGER ADAMS 1950 39 With }. B. Campbell. Restricted rotation in aryl amines. VIII. Ring nitrogen derivatives of diaminomesitylene. }. Am. Chem. Soc., 72: 128-32. With N. K. Nelson. Restricted rotation in aryl amines. IX. Diamino- durene derivatives. I. Am. Chem. Soc., 72:132-35. With B. Englund. Restricted rotation in aryl amines. X. Stereoi- somers of N,N',N "-trialkyl-N,N',N "-tribenzenesulfonyltri- amino-mesitylenes. l. Am. Chem. Soc., 72: 13~38. With l. Campbell. Hindered tetraarylmethanes. I. Am. Chem. Soc., 72: 15~55. With W. Herz. Synthesis of viridifloric acid. l. Am. Chem. Soc., 72: 15~57. With T. R. Govindachari. Structure of monocrotaline. XII. Mono- crotalic acid. I. Am. Chem. Soc., 72: 158-63. With W. M. Whaley. The amaroids of quassia. I. Quassin, isoquas- sin and neoquassin. I. Am. Chem. Soc., 72:375-79. With }. Campbell. 2,4,5- and 2,4,7-trimethylquinolines. }. Am. Chem. Soc., 72:1021-22. With F. L. Warren, M. Kropman, T. R. Govindachari, and I. H. Looker. The identity of,l3-longilobine with retrorsine. }. Am. Chem. Soc., 72: 1421-22. With A. S. Nagarkatti.2,4- and 4,6-dinitro- and diamino~n-xylenes. I Am. Chem. Soc., 72:1831-32. With I. R. Gordon. Restricted rotation in aryl amines. XI. Influence of groups decreasing the basicity of the nitrogen atom. J. Am. Chem. Soc., 72:245~57. With I. R. Gordon. Restricted rotation in aryl amines. XII. Resolu- tion of certain N-benzenesulfonyl-N-carboxymethyl derivatives. }. Am. Chem. Soc., 72:2458-60. With A. S. Nagarkatti. Quinone imides. I. p-Quinone disulfoni- mides. J. Am. Chem. Soc., 72:4601-6. With A. S. Nagarkatti. Restricted rotation in aromatic amines. XIII. The effect of monosubstitution in the ortho position. J. Am. Chem. Soc., 72:460~8. With N. K. Nelson. Restricted rotation in aryl amines. XIV. Iso- propyl derivatives of dibenzenesulfonamidomesitylene. I Am. Chem. Soc., 72:5077-79. With J. L. Johnson and B. Englund. Polymers of c~-acetamidoacrylic acid and its methyl ester. l. Am. Chem. Soc., 72:508(~82.

40 BIOGRAPHICAL MEMOIRS With T L. Anderson. Quinone imides. II. p-Quinone diacyl and diaroylimides. I. Am. Chem. Soc., 72:515~57. 1951 With R. A. Wankel. Quinone imides. III. 1,4-Naphthoquinone di- sulfonimides. I. Am. Chem. Soc., 73:131-34. With I. H. Looker. The identity of a-longilobine and seneciphyl- line. }. Am. Chem. Soc., 73: 13~36. With I. L. Anderson. The effect of c-methyl substituents on the anhydridization of aliphatic dibasic acids. I. Am. Chem. Soc., 73: 13~41. With i. H. Looker. Quinone imides. IV. p-Quinone monosulfoni- mides. l. Am. Chem. Soc., 73: 114~49. With K. R. Eilar. Quinone imides. V. Aluminum chloride-catalyzed arylations of p-quinone dibenzenesulfonimides. }. Am. Chem. Soc., 73:114~52. With C. R. Walter, {r. Quinone imides. VI. Addition of dienes to p-quinone sulfonimides. i. Am. Chem. Soc., 73:1152-55. With R. A. Wankel. Quinone imides. VII. 1,2- and 2,6-naphtho- quinone disulfonimides. I. Am. Chem. Soc., 73:221~20. With C. N. Winnick. Quinone imides. VIII. Synthesis and reactions of o-quinone diimides. }. Am. Chem. Soc., 73:5687-91. 1952 With F. B. Hauserman. The total structure of monocrotaline. XIII. Synthesis of dihydroanhydromonocrotalic acid. I. Am. Chem. Soc., 74:694-99. With T. R. Govindachari, I. H. Looker, and I. D. Edwards, Jr. Senecio alkaloids: c~-longilobine; structure of c'-longinecic acid. }. Am. Chem. Soc., 74:700-703. With W. Moje. Quinone imides. IX. Addition of dienes to 1,4- naphthoquinonedibenzenesulfonimide. J. Am. Chem. Soc., 74:2593-96. With K. A. Schowalter. Quinone imides. X. Addition of amines to p-quinonedibenzenesulfonimide. J. Am. Chem. Soc., 74: 2597-602. With I. D. Edwards, Jr. Quinone imides. XI. Addition of dienes to p-quinonedibenzenesulfonimide. J. Am. Chem. Soc., 74: 2603-4.

ROGER ADAMS 41 With }. D. Edwards, Jr. Quinone imides. XII. Addition of dienes to p-quinonemonobenzenesulfonimide. I. Am. Chem. Soc., 74: 2605-7. With E. F. Elslager and K. F. Heumann. Quinone imides. XIII. Orientation of groups in adducts of hydrogen chloride with quinone diimides. I. Am. Chem. Soc., 74:2608-12. With D. S. Acker. Quinone imides. XIV. Addition of hydrogen chloride to p-quinonedibenzimides and related compounds. I. Am. Chem. Soc., 74:3029-32. With R. R. Holmes. Quinone diimides. XV. Diphenoquinonedi- imides. l. Am. Chem. Soc., 74:3033-37. With R. R. Holmes. Quinone diimides. XVI. Diphenoquinonedi- imides. }. Am. Chem. Soc., 74:3038-41. With B. H. Braun. Chlorination of benzenesulfonyl derivatives of aromatic amines. I. Am. Chem. Soc., 74:3171-73. With D. S. Acker. Quinone imides. XVII. Addition of organic acids top-quinonedibenzimide and related compounds. I. Am. Chem. Soc., 74:3657-59. With I M. Stewart. Quinone imides. XVIII. p-Quinonedipival- imides and their reactions. l. Am. Chem. Soc., 74:3660-64. With Irwin }. Pachter. Structure of the 2-pyridone and a-bromoacrylic acid adduct and its derivatives. I. Am. Chem. Soc., 74:4906-9. With B. L. Van Duuren. Trachelanthic and viridifloric acids. I. Am. Chem. Soc., 74:5349-51. With T. E. Bockstahler. Preparation and reactions of o- hydroxycinnamic acids and esters. }. Am. Chem. Soc., 74: 5346-48. With I. I. Pachter. Ultraviolet spectra and structures of the pyridoll,2-a]-pyrimidones. I. Am. Chem. Soc., 74:5491-97. With W. Moje. Quinone imides. XIX. Addition of active methylene compounds to 1,4-naphthoquinonedibenzenesulfonimide. I. Am. Chem. Soc., 74:5557-60. With W. Moje. Quinone imides. XX. Additions to 1,4-naphtho- quinonedibenzenesulfonimide. J. Am. Chem. Soc., 74:5560-62. With W. Moje. Quinone imides. XXI. Addition of hydrogen cya- nide to 1,4-naphthoquinonedibenzenesulfonamide. J. Am. Chem. Soc., 74:5562-63. With R. S. Voris and L. N. Whitehill. Restricted rotation about the aliphatic carbon-carbon bond. }. Am. Chem. Soc., 74:5588-92.

42 BIOGRAPHICAL MEMOIRS With B. L. Van Duuren and B. H. Braun. The structure of mono- crotaline. XIV. Synthesis of monocrotalic acid. }. Am. Chem. Soc., 74:5608-11. With P. R. Shafer and B. H. Braun. The structure of monocro- taline. XV. I. Am. Chem. Soc., 74:5612- 15. With B. H. Braun. Quinone imides. XXII. The reaction of primary aromatic amines with 2,3,5,6-tetrachloro1-quinonedibenzene- sulfonimide. }. Am. Chem. Soc., 74:5869-71. With D. S. Acker. Quinone imides. XXIII. Addition reactions of p-quinonedibenzimide and related compounds. }. Am. Chem. Soc., 74:5872-76. With I. M. Stewart. Quinone imides. XXIV. o-Quinonemono- imides. I. Am. Chem. Soc., 74:5876-80. 1953 With E. F. Elslager and T. E. Young. Quinone imides. XXV. Addi- tion of mercaptans to p-quinonedibenzenesulfonimide. I Am. Chem. Soc., 75:663-66. With P. R. Shafer. Quinone imides. XXVI. Adducts of p- quinonebis~dimethylaminosulfonimides) and their hydrolysis products. I. Am. Chem. Soc., 75:667-70. With D. C. Blomstrom. Restricted rotation in aryl amines. XV. Stereoisomeric diglutarimidomesitylenes. I. Am. Chem. Soc., 75:2375-77. With B. L. Van Duuren. Dicrotaline. The structure and synthesis of dicrotalic acid. }. Am. Chem. Soc., 75:2377-79. With T. E. Young. Quinone imides. XXVII. Addition reactions of substituted p-quinonedibenzenesulfonimides. I Am. Chem. Soc., 75:3235-39. With D. C. Blomstrom. Quinone imides. XXVIII. Addition of ac- tive methylene compounds to p-quinonedibenzenesulfonimide and its derivatives. J. Am. Chem. Soc., 75:3403-5. With D. C. Blomstrom. Quinone imides. XXIX. Addition of hydra- zoic acid and phenols top-quinonedibenzenesulfonimide and its derivatives. }. Am. Chem. Soc., 75:3405-8. Uber die Chemie der Senecio-Alkaloide und verwandter Verbin- dungen. Angew. Chem., 65:433-42. With B. L. Van Duuren. Usaramoensine, the alkaloid in Crotalaria usaramoensis E. G. Baker. Integerrimine from Crotalaria incana

ROGER ADAMS 43 Linn and senecionine from Senecio globellus D. C. Stereochemical relationships. I. Am. Chem. Soc., 75:4631-35. With B. L. Van Duuren. Structure of heliotrinic acid. I. Am. Chem. Soc., 75:4636-38. With B. L. Van Duuren. Riddelliine, the alkaloid from Senecio rid- delii. II. Structure of riddellic acid and total structure of riddel- liine. l. Am. Chem. Soc., 75:4638~2. With B. H. Braun and S. H. Pomerantz. Quinone imides. XXX. Addition of primary and secondary aromatic amines. I. Am. Chem. Soc., 75:4642-44. With R. R. Holmes and }. W. Way. Quinone imides. XXXI. 3,3-Dimethoxydiphenoquinonedibenzenesulfonimide and its reaction products. I. Am. Chem. Soc., 75:5901-4. 1954 With S. H. Pomerantz. Quinone imides. XXXII. Reactions of 1,4-naphthoquinonedibenzenesulfonimide with pyridine and its derivatives. }. Am. Chem. Soc., 76:702-6. With T. E. Young and R. W. P. Short. Quinone imides. XXXIII. Orientation of adducts from 2-benzenesulfonyl1-quinonedi- benzenesulfonimide. I. Am. Chem. Soc., 76: 1114-18. With I. }. Pachter. The action of alkali on bromopyridopyri- midones. J. Am. Chem. Soc., 76:1845-47. With R. W. P. Short. Quinone imides. XXXIV. Addition of dienes to substituted p-quinonedibenzenesulfonimides. J. Am. Chem. Soc., 76:2408-10. With I. W. Way. Quinone imides. XXXV. o-Quinonedibenzimides. I. Am. Chem. Soc., 76:2763-69. With S. Miyano. 2-Aminopyridine 1-oxides. J. Am. Chem. Soc., 76:2785-86. With S. Miyano. Condensation reactions of picoline 1-oxides. Am. Chem. Soc., 76:3168-71. J With R. S. Colgrove. Quinone imides. XXXVI. Orientation of groups in adducts of quinone diimides with different N- substituents. J. Am. Chem. Soc., 76:3584-87. With R. H. Mattson. Restricted rotation in aryl amines. XVI. 4-Substituted 1-amino-2-methylnaphthalenes. J. Am. Chem. Soc., 76:4925-28. With K. V. Y. Sundstrom. Restricted rotation in aryl amines. XVII. Effect of varying the 4-substituent on the stability of optically

44 BIOGRAPHICAL MEMOIRS active N-benzenesulfonyl-N-carboxymethyl- 1-amino-2-methyl- naphthalene. }. Am. Chem. Soc., 76:547~77. With D. C. Blomstrom and K. V. Y. Sundstrom. Restricted rotation in aryl amines. XVIII. Resolution of N-carboxymethyl-N- methyl-3-bromomesidine. }. Am. Chem. Soc., 76:5478-79. With B. L. Van Duuren. Stereochemistry of the pyrrolizidine bases. I. Am. Chem. Soc., 76:6379-83. 1955 With W. P. Samuels, Jr. Quinone imides. XXXVII. Conversion of p-quinone diimides to indoles. }. Am. Chem. Soc., 77:5375-82. With W. P. Samuels, Jr. Quinone imides. XXXVIII. Adducts to p-quinonedimethanesulfonimide and their hydrolysis products. }. Am. Chem. Soc., 77:5383-85. With E. I. Agnello and R. S. Colgrove. Quinol imides and o-quinone imide diacetates. I. Conversion of 4-benzenesulfonamidotri- phenylmethane to 4-benzohydryl - -quinonediacetatebenzene- sulfonimide. }. Am. Chem. Soc., 77:5617-25. 1956 With M. Gianturco. Senecio alkaloids. The corr~position of"hieraci- foline" and "jacobine." }. Am. Chem. Soc., 78:398-400. With L. Whitaker. Quinone imides. XXXIX. Adducts of quinone monoimides and conversion of active methylene adducts to ben- zofurans. }. Am. Chem. Soc., 78:658-62. With K. R. grower. Restricted rotation in aryl amines. XVIII. Ef- fect of remote substituents on the stability of optically active N-benzenesulfonyl-N-carboxymethyl-3-benzylmesidine. l. Am. Chem. Soc., 78:663-66. With M. Gianturco. The alkaloids of Crotalariajuncea. J. Am. Chem. Soc., 78:1919-21. With M. Gianturco. Senecio alkaloids. Structure of trichodesmine. }. Am. Chem. Soc., 78:1922-25. With M. Gianturco. Crotalaria alkaloids. The structure of junceine. I. Am. Chem. Soc., 78:1926-28. With M. Gianturco and B. L. Van Duuren. The alkaloids from Senecio tomentosus. Observations on the alkaloid jacobine and on the structure of jaconecic acid. I Am. Chem. Soc., 78:3513- 19.

ROGER ADAMS 45 With W. Reifschneider. Addition of phenylmagnesium bromide to aliphatic conjugated dibenzenesulfonimides. l. Am. Chem. Soc., 78:3825-28. With M. Gianturco. The structures of grantianine and sceleratine. A suggested biogenesis of the acids in alkaloids from Senecio and Crotalaria species. I. Am. Chem. Soc., 78:4458~4. With K. R. grower. Quinol imide acetates. 2,4,6-Trimethyl - - quinobenzenesulfonimide acetate and 2,4-dimethyl-o-quinol- benzenesulfonimide acetate. {. Am. Chem. Soc., 78:4770-73. With I. E. Dunbar. Quinol imide acetates. III. Addition reactions of 2-methyl - -naphthoquinoll-toluenesulfonimide acetate. I. Am. Chem. Soc., 78:4774-78. With M. Gianturco. Senecio alkaloids: the alkaloids of Senecio brasil- iens?s, fremonti and ambrosioides. J. Am. Chem. Soc., 78:5315-17. With M. D. Nair. Quinone imides. XL. Orientation in addition of hydrogen chloride to 2-substituted p-quinonedibenzimides. I. Am. Chem. Soc., 78:5927-31. With M. D. Nair. Quinone imides. XLI. Orientation in addition of thiophenol and benzenesulfinic acid to 2-substituted p-qui- nonedibenzimides. l. Am. Chem. Soc., 78:5932-38. 1957 With M. Gianturco. Senecio alkaloids: mikanoidine, the alkaloid from Senecio mikanoides. ]. Am. Chem. Soc., 79: 166 69. With H. H. Gibbs. Restricted rotation in aryl amines. XIX. Effect of substituents in the 4-position on the optical stability of 1-amino-2-methylnaphthalene derivatives. J. Am. Chem. Soc., 79: 170-73. With M. Gianturco. Senecio alkaloids: spartioidine, the alkaloid from Senecio spartioides; stereochemical relationship to other Senecio alkaloids. I. Am. Chem. Soc., 79:174-77. With M. D. Nair. Quinone imides. XLII. Orientation of adducts from substituted p-quinonedimethanesulfonimides. I. Am. Chem. Soc., 79:177-79. With E. L. DeYoung. Quinone imides. XLIII. The reactions of o-quinonedibenzenesulfonimides. J. Am. Chem. Soc., 79: 417-19. With E. L. DeYoung. Quinol imide acetates. IV. The reactions of 2,4-dimethyl - -naphthoquinol1-toluenesulfonimide acetate. I. Am. Chem. Soc., 79:705-8.

46 BIOGRAPHICAL MEMOIRS With W. Reifschneider. The reaction of 2-bromopyridine N-oxides with active methylene compounds. {. Am. Chem. Soc., 79: 223~39. With H. I. Neumiller, fir. Quinone imides. XLIV. The orientation of groups in addition reactions to substituted p-quinonedi- benzimides. I. Am. Chem. Soc., 79:3808-12. With M. I. Gortatowski. Restricted rotation in arylamines. XX. Ef- fect of meta substitution on the optical stability of some N- benzenesulfonyl-N-carboxymethylmesidines. I. Am. Chem. Soc., 79:5525-28. 1958 With L. M. Werbel and M. D. Nair. Quinone imides. XLVI. Addi- tion of heterocyclic active methylene compounds to p-benzo- quinone diimides. I. Am. Chem. Soc., 80:3291-93. With I. E. Dunbar. Restricted rotation in arylamines. XXII. N- benzenesulfonyl-N-carboxymethyl-3-amino-2,4,6-trimethylpyri- dine and its N-oxide. I. Am. Chem. Soc., 80:3649-51. With I. S. Dix. Restricted rotation in arylamines. XXI. Effect of 3-substituents on the optical stability of some N-benzene- sulfonyl-N-carboxymethylmesidines. I. Am. Chem. Soc., 80: 4579-81. With I. S. Dix. Reaction of 2-aminopyridine with a-haloketones. J. Am. Chem. Soc., 80:4618-20. With L. M. Werbel. Preparation of quinol imide acetates. VI ~ Scope and limitations. I. Am. Chem. Soc., 80:5799-803. 1959 With W. Reifschneider. A synthesis of 6-hydroxy-4-quinolizones. I. Am. Chem. Soc., 81:2537-41. With A. Ferretti. Thioethers from halogen compounds and cu- prous mercaptides. II. {. Am. Chem. Soc., 81:4927-31. With A. Ferretti. Thioethers. III. Preparation of aromatic di- and tri-mercapto compounds by dealkylation off aryl alkyl thio- ethers. I. Am. Chem. Soc., 81:4939-40. With D. Fles. The absolute configuration of the Cat atom in retrone- canone ~ 1-methyl-7-oxopyrrolizidine). J. Am. Chem. Soc., 81 :494~51. With D. Fles. The absolute configuration of the Cal atom in pyrro-

ROGER ADAMS 47 lizidine moieties of Senecio alkaloids. T Am. Chem. Soc.. 81 :5803-5. With C. C. I. Culvenor, C. N. Robinson, and H. A. Stingl. Synthesis of heliotramide. Aust. T. Chem., 12: 70~ 11. 1960 With S. Miyano and D. Fles. 1-Hydroxypyrrolizidine and related compounds. I. Am. Chem. Soc., 82:146~68. With M. D. Nair. Stereochemistry of necic acids. }. Am. Chem. Soc., 82:378~87. With T. A. Geissmann and J. D. Edwards. Gossypol, a pigment of cottonseed. Chem. Rev., 60:555-74. 1961 With M. D. Nair. The structure of riddellic acid and the stereo- chemistry of necic acids. ]. Am. Chem. Soc., 83:922-26. With A. Ferretti. Restricted rotation in aryl amines. XXII. Effect of meta substitution on the optical stability of some N-benzene- sulfonyl-N-carboxymethylmesidines. I Am. Chem. Soc., 83: 2559-63. With S. Miyano and M. D. Nair. Synthesis of substituted pyrro- lidines and pyrrolizidines. ]. Am. Chem. Soc., 83:3323-27. With M. D. Nair. Benzimidazole syntheses by oxidative cyclization with peroxytrifluoroacetic acid. I. Am. Chem. Soc.,83:3518-21.

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Biographic Memoirs: Volume 53 contains the biographies of deceased members of the National Academy of Sciences and bibliographies of their published works. Each biographical essay was written by a member of the Academy familiar with the professional career of the deceased. For historical and bibliographical purposes, these volumes are worth returning to time and again.

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