Strategies That Influence Cost Containment in Animal Research Facilities (2000) / Chapter Skim
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Executive Summary
Executive Summary
Pages 1-5
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Develop recommendations by which federal auditors and research institutions can establish what cost components of research animal facilities should be charged to institutions' indirect cost pool and what animal research facility cost components should be included in the per diem charges to investigators, and assess the financial and scientific ramifications that these criteria would have among federally funded institutions. The results of this phase of the study were released in an interim report within 6 months of receipt of funding.
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, conducted by the Yale University School of Medicine's Section of Comparative Medicine; published data; and the collective experience of the committee members. The report covers cost of personnel, laboratory animal management, veterinary medical care, equipment and facility design, compliance with regulations, and future directions in research that uses animals.
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The mix of species, the presence or absence of a surgery program, and the use of animal models that require intensive veterinary assistance because of experimental complications, invasive procedures, or spontaneous disease are determining factors in the amount of veterinary input required. In general, rodentonly programs require less clinical veterinary support than surgeryintensive programs and programs that use larger species extensively.
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From page 4... ...
Increasing cen-tralization results in increased labor productivity and decreased cost of operation per square foot a finding that should be considered when renovations or expansions of animal research facilities are contemplated. Decreasing the costs of animal husbandry involves consideration of type of caging (conventional, microisolator, or individually ventilated caging)
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From page 5... ...
Many factors will contribute to increased mouse use over the next few years: the genome project and functional genomics, interinstitutional transfer of various mouse lines, conditional and tissue-specific mutations, chemical and viral mutagenesis, creation of therapeutic models, and in viva gene-transfer experiments. In light of those factors, many institutions are projecting at least a threefold increase over 5 years.
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