Acute Exposure Guideline Levels for Selected Airborne Chemicals Volume 1 (2000) / Chapter Skim
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Introduction
Introduction
Pages 1-8
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This tragedy served to focus international attention on the need for governments to identify hazardous substances and to assist local communities in planning how to deal with emergency exposures. In the United States, the Superfund Amendments and Reauthorization Act (SARA)
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The National Research Council (NRC) Committee on Toxicology (COT)
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of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death. Airborne concentrations below AEGL- ~ represent exposure levels that can produce mild and progressively increasing but transient and nondisabling odor, taste, and sensory irritation or certain asymptomatic, nonsensory effects.
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For most chemicals, actual human toxicity data are not available or critical information on exposure is lacking, so toxicity data from studies conducted in laboratory animals are extrapolated to estimate the potential toxicity in humans. Such extrapolation requires experienced scientific judgment.
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Washington, DC: National Academy of Sciences. NRC (National Research Council)
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Washington, DC: National Academy Press. NRC (National Research Council)
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NRC (National Research Council)
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