Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals (2001) / Chapter Skim
Currently Skimming:
4 Current Administrative Processes and Procedures for the Development of AEGL Values
4 Current Administrative Processes and Procedures for the Development of AEGL Values
Pages 139-153
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 139... ...
environmental restoration, waste management, and fixed facility programs; the Agency for Toxic Substances and Disease Registry (ATSDR) health consultation and risk assessment programs; the National Institute for Occupational Safety and Health SLOSH)
|
From page 140... ...
This objective is accomplished through the development and maintenance of a comprehensive standing operating procedures (SOP) manual that addresses the scientific and administrative procedures required to achieve the objectives of the NAC/AEGL Committee.
|
From page 141... ...
From time to time, the members of the committee serve as chemical managers and chemical reviewers in a collaborative effort with assigned scientist authors (noncommittee members) to develop AEGLs for a specific chemical.
|
From page 142... ...
. l | NAS-NRC AEGL |, /ACIAEGL\ | Subcommittee r \2ommiKee' - 1 \: /AS-NRC AEGL\ YES ~ Subcommittee 1 \~ FIGURE 4-1 The AEGL development process.
|
From page 143... ...
and this SOP manual, and selected data are used as the basis for the derivation of the AEGL values and the supporting scientific rationale. Data evaluation, data selection, and the development of a TSD are all performed as a collaborative effort among the staff scientists at the organization that drafts TSDs, the chemical manager, and two chemical reviewers.
|
From page 144... ...
Stage 3: Interim AEGEs Following resolution of relevant issues raised through public review and comment and subsequent approval of the committee, the AEGL values are classified as interim. The interim AEGL status represents the best efforts of the NAC/AEGL Committee to establish exposure limits, and the values are available for use as deemed appropriate on an interim basis by federal and state regulatory agencies and the private sector.
|
From page 145... ...
Reviews, comments, and revisions are continuous up to the time of the meeting, and committee members are expected to be familiar with the draft, proposed, or interim AEGLs, supporting rationale, and other data and information in each TSD and to participate in the resolution of residual issues at the meeting. Procedures for the AEGL Development Teams and the other committee members regarding work on AEGLs in proposed or interim status are similar to those for draft AEGLs.
|
From page 146... ...
As mentioned in Chapter I, a Standing Operating Procedures Workgroup (SOP Workgroup) , established in March 1997, documents, summarizes, and evaluates the various procedures, methodologies, and guidelines used by the committee in the gathering and evaluation of scientific data and information and in the development of the AEGL values.
|
From page 147... ...
The DFO serves as an executive secretariat to the NAC/AEGL Committee and is responsible for the following: Effective communication and coordination with NAC/AEGL Committee members, the committee chair, the organization that drafts TSDs, and interested parties in the public and private sectors. Day-to-day administrative management ofthe NAC/AEGL Committee with respect to the agenda for future meetings, distribution of TSDs and other correspondence with committee members, maintenance of meeting minutes, tapes of meetings and other important committee records, funding and other financial matters, and committee membership matters.
|
From page 148... ...
4.8 FUNCTION OF AEGL DEVELOPMENT TEAMS Each AEGL Development Team consists of a staff scientist from the organization that drafts TSDs, a chemical manager, and two chemical reviewers who are members of the NAC/AEGL Committee. The primary function ofthe NAC/AEGL Development Team is to provide the NAC/AEGL Committee with draft AEGL values and a TSD containing relevant data and information on the chemical and the derivation ofthe draft AEGEs.
|
From page 149... ...
It is expected that the chemical manager will achieve a consensus within the AEGL Development Team on the issues related to the development ofthe AEGI, values prior to the meeting ofthe full NAC/AEGL Committee. Further, as time permits, the chemical manager will attempt to resolve issues raised by individual committee members prior to the scheduled committee meeting.
|
From page 150... ...
Serve as liaison between NAC/AEGL Committee members and the staff scientist during the development of draft AEGL values and the TSD. Resolve scientific issues prior to the NAC/AEGL Committee meetings, such as the following: Completeness of data gathering (published and unpublished)
|
From page 151... ...
4.~.3 Role of a Staff Scientist at the Organization That Drafts TSDs The staff scientist has the primary responsibility for data gathering, data evaluation, identification of potential key data and supporting data, identification of potential methodologies, calculations, and extrapolations, and the preparation of the TSD. The following tasks are included: Participate as a member of the ad hoc AEGL Development Team.
|
From page 152... ...
Provides the staff scientists and the administrative personnel with the facilities and equipment necessary for data gathering, maintenance of databases, dissemination of relevant information to committee members, presentations or co-presentations (with chemical managers) at the NAC/AEGL Committee meetings, development and revisions of TSDs, preparation of submissions to the Federal Register, summarization of Federal Register comments and identification of important scientific issues, presentations to the committee on Federal Register
|
From page 153... ...
The initial distnbuted version will be without the AEGL values and the rationale used to derive them and will occur between ~ and 14 days before the committee meeting.
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.