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Stem Cells and the Future of Regenerative Medicine (2002) / Chapter Skim
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Pages 89-94

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From page 89...
... . Oplmon Autoimmune diseases, 8 diabetes, 8, 28,35, 84 Autologous transplants, 24, 27 defined, 67 B B cells, 20 Birth defects, 8 Blastocysts, 13, 14,31,32,37 cloning, 11 defined, 67 inner cell mass, 15,31,37, 70; see also Embryonic stem cells Blood, see Hematopoietic stem cells Bone cells, 16, 28, 79 Bone marrow stem cells see also Hematopoietic stem cells adult, 2, 7, 16, 19, 21, 41, 58 committee workshop agenda, 79 defined, 67-68 89
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From page 90...
... 2-3, 17, 56 animal models, 32-34, 35, 36 bone marrow, 32,33 brain, 32, 38 cancer, 32, 34, 36, 38 cardiovascular system, 32, 33 cloning vs. 11 committee recommendations, 5, 41-42, 43, 56 committee workshop agenda, 79-81 defined, 13, 68-69 differentiation, 7-8, 19, 21,32-33,34, 36-38 feeder cells, 33, 36 funding for research, 3-4, 5,35, 49-51, 58,59 hematopoietic, 32, 33, 34, 35, 47 hepatic, 34, 38 immune system, 34-35, 36, 38-39, 47 multipotent, 16,32,33-34, 41 muscle, 32, 33 neural stem cells, 8, 15,32, 33-34,35 pancreatic, 32, 34-35, 36 plasticity, 41; see also "multipoterlt" supra private sector, 3, 49-51 renal, 34-35 skin, 16,33 90
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From page 91...
... 11, 47 defined, 13-14 Food and Drug Administration, 54, 80, 86 France, 46 Funding, 48-54, 57-58 embryonic stem cells, 3-4, 5, 35, 49-51, 58,59 private sector, 3, 49-52, 57 report at hand, xi, 9 research, general, 3-4, 51-52 G Genetic disorders, 8, 17, 84 adult stem cells, 24 Germany, 46 Germ cells, 16 defined, 69 Gonadal ridge, 16 defined, 69 germ cells, 16, 69 Graft-versus-host disease, 21-22 defined, 69 H Hematopoietic stem cells (HSCs) , 56 adult, 16, 19-23, 25, 26, 29, 47 animal models, 21, 23, 25, 29 defined, 69 differentiation, 19, 20 embryonic, 32, 33, 34, 35, 47 fetal, hepatic system, 13, 16, 29, 80 T cells, 20, 21 Hepatic system, 7 adult stem cells, 23, 26 committee workshop agenda, 79-80 defined, 69 embryonic stem cells, 34, 38 fetal hematopoietic stem cells, 13, 16, 29, 80 Histocompatibility, 4, 21 adult stem cells, 21-22, 24, 26 autologous transplants, 24, 27, 67 committee recommendations, 5 defined, 69 embryonic stem cells, 34-35, 36, 38-39 47 graft-versus-host disease, 21-22, 69 immunosuppressive drugs, 4, 34 transplant rejection, 4, 10, 12, 21-22, 24, 34-35, 36, 38-39, 47, 58 Immune system see also Histocompatibility adult stem cells, 19, 21-22, 24, 26 antigens, 67, 71 surface antigen, 22-23, 38, 71, 72 autologous transplants, 24, 27, 67 91
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From page 92...
... , 5, 53, 58 recent report, 10 Neoplastic growth, see Cancer Neural crest cells fetal, 13-14, 16 Neural stem cells see also Brain adult, 16,21,23,24,26,27,28 Alzheimer's disease, 8 animal models, 13, 27 committee workshop agenda, 80 defined, 71 embryonic, 8,15, 32, 33-34, 35 fetal, 13 Parkinson's disease, 8, 13, 27, 35, 84 spinal-cord injuries, 8, 83 Neurons defined, 71 dendrites, 38, 68 92
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From page 93...
... Index o Osteoporosis, 8 Ovum, 13, 14, 15, 37 cloning, 11 defined, 71 p Pancreas adult stem cells, 23, 26 committee workshop agenda, 80 diabetes, 8, 16, 28, 35, 84 embryonic stem cells, 32, 34-35, 36 fetal stem cells, 13, 16 Parkinson's disease, 8, 13, 27, 35, 84 Pharmaceuticals, see Drugs, immunosuppressive Philosophical, ethical and legal issues, xixli, 1, 3-5, 10, 12, 43-48, 50, 51-53, 55, 57-58, 85, 86-87 adult stem cell research, 47 committee workshop agenda, 80-81 DNA research, 3-4, 51-53, 58 international perspectives, 46, 80 public opinion, xi, 1, 52-53, 55, 57 religious, 44-45 Placenta, 16 defined, 71 Plasticity see also Multipotent stem cells adult stem cells, 16, 24, 25, 26, 28, 41, 47 defined, 12, 71 embryonic stem cells, 41 Pluripotent stem cells, see Multipotent stem cells Private sector, 3, 49-52, 57, 85 committee workshop agenda, 80 Progenitor cells hematopoietic, 20 pancreatic, 13 Proteins, adult stem cells, 12, 22, 26-27 Public opinion, xi, 1, 52-53, 55, 57 religious issues, 44-45 R Religious, 44-45 Renal system embryonic stem cells, 34-35 Reproductive system see also terms i~egir~r~ir~g "Emi7ryo," arid "Fetal" cloning, 10, 11, 48 in vitro fertilization, 43, 48, 70 ovum, 11, 13, 14, 15, 37, 71 placenta, 16, 71 umbilical cord, 16, 22 zygotes, 13, 14, 15, 37, 72 S SCNT, see Somatic cell nuclear transfer technique Skin cells, 7, 13, 16 adult stem cells, 21, 23, 27, 33, 41 burns, 8 embryonic stem cells, 16, 33 Smooth muscle cells, 15 Somatic cell nuclear transfer (SCOT) , 5, 10, 11, 12, 37, 39, 45, 46, 47, 59 Somatic cells, general, 29 committee recommendations, 5 defined, 71 Spinal-cord injuries, 8, 83 Stromal cells, 33 defined, 71 Surface antigens, 22-23, 38, 71 defined, 72 T T cells defined, 72 hematopoietic stem cells, 20, 21 Trophoblasts, 13 93
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From page 94...
... STEM CELLS AND THE FUTURE OF REGENERATIVE MEDICINE U Umbilical cord, 16, 22 Undifferentiated cells, see Differentiation United Kingdom, 46 W White blood cells see also Hematopoietic stem cells; Lymphocytes; T cells defined, 72 World Wide Web, see Internet z Zygotes, 13,14,15, 37 defined, 72 94
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Key Terms

  • embryonic stem
  • adult stem
  • hematopoietic stem
  • committee workshop
  • fetal stem

  • marrow stem
  • legal issues
  • neural stem
  • bone marrow
  • fetal hematopoietic

  • cells fetal
  • cells bone
  • stem cell
  • workshop agenda
  • animal models

  • cells adult
  • committee recommendations
  • germ cells
  • private sector
  • autologous transplants

  • crest cells
  • brain adult
  • feeder cells
  • inner cell
  • cell mass

  • neural crest
  • immunosuppressive drugs
  • surface antigen
  • neoplastic growth
  • transplant rejection


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