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Cancer and the Environment Gene-Environment Interaction (2002) / Chapter Skim
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8. Moving Forward
Pages 65-69

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From page 65...
... The populations with disparities include Hispanics, American Indians, Alaska Natives, Asian and Pacific Islanders, African Americans, Native Hawaiians, blue-collar workers, rural, elderly, and low-income and low-literacy groups. They not only carry a higher burden of cancer, but also are more prone to other diseases and societal problems.
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From page 66...
... For these reasons, many panelists and speakers urged participants to conduct additional research on special populations to address disparities in incidence rates, mortality rates, and access to care in these populations and to put a greater emphasis on environmental disease surveillance including more complete cancer registries across all populations. CANCER PREVENTION Presentations throughout the two days highlighted the fact that many lifestyle and environmental carcinogens have been identified by investigating cancer in populations and that this knowledge has led to new approaches for reducing cancer risk.
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From page 67...
... FUTURE RESEARCH AREAS Mounting evidence indicates that mutation patterns detected in certain tumors may be distinct enough to provide a molecular fingerprint that is traceable to specific environmental agents. In large, population-based studies now under way, investigators described how they are exploring the way in which genetic factors and environmental exposures, including those related to lifestyle and diet, interact to influence cancer risk.
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From page 68...
... Large epidemiologic consortia could pool data and publish results from several independent investigations simultaneously to quickly determine whether a given result in one study is supported by other studies. Such consortia would facilitate the pooling of data to assess rare subtypes, or combine data from multiply infected families, and would improve reproducibility and other quality control measures.
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From page 69...
... POLICY IMPLICATIONS Since the Cancer Act of 1972, many reports on cancer have discussed the policy implications of current cancer research. The Institute of Medicine has released a number of these, including Ensuring Quality Cancer Care and The Unequal Burden of Cancer.
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Key Terms

  • cancer research
  • cancer registry
  • cancer risk
  • cancer registries
  • cancer incidence

  • genetic factors
  • special populations
  • genetic predisposition
  • environmental carcinogens
  • mortality rates

  • developing cancer
  • registry data
  • environmental exposures
  • risk patterns
  • speakers urged

  • seer program
  • research implications
  • control measures
  • workshop highlighted
  • risks increase

  • infectious agents
  • allow broad
  • evidence indicates
  • alterations suggesting
  • genetic susceptibilities

  • conduct additional
  • genetic patterns
  • endogenous hormone
  • rare subtypes
  • native hawaiians


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