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1. Charge to Participants and Workshop Objectives
Pages 7-10

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From page 7...
... When the Roundtable met in September of 2000, it became evident that this was an ideal time to hold a workshop on gene-environment interactions in cancer because of two recent advances in genetics and environmental studies. The first advance is the completion of an initial draft sequence of the human genome.
From page 8...
... It is this expanded view of environmental health that will allow us to conduct more meaningful and precise studies of environmental contributions to cancer. Although the research model of the rare dominant cancer gene, or the strong environmental toxicant, has served us well in the past in defining the molecular biology of cancer, it will not be sufficient in the future.
From page 9...
... Complex interactions require future research on individual susceptibilities, examining how multiple modifier genes interact with the environment. Since the 1960s we have been developing the field of occupational health along a particular paradigm that has three main questions.
From page 10...
... We will discuss many of the opportunities for areas of future research and prevention. Finally, we will use the broader perspective of environments one that encompasses the effects of the social, built (including occupational)


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