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Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research (2003) / Chapter Skim
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1 Regulatory and Ethical Considerations
Pages 5-11

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From page 7...
... , detailed standards and regulations that govern many aspects of animal care and use programs, including registration of research facilities, institutional animal care and use committees (IACUCs) , the attending veterinarian and adequate veterinary care, recordkeeping, reporting, and the procurement, handling, care, treatment, and transportation of animals (9 CFR, Part 2, Subpart C)
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From page 8...
... , the PHS Policy requires institutions to establish and maintain proper measures to ensure the appropriate care and use of animals involved in research, research training, and biologic testing activities. The PHS Policy mandates compliance with the AWA and the AWRs and requires institutions to base their programs of animal care and use on the National Research Council's Guide for the Care and Use of Laboratory Animals (NRC, 1996~.
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From page 9...
... Both PHS Policy and the Association for Assessment and Accreditation of Laboratory Animal Care International require that institutions base their programs of animal care and use on the Guide. The Guide is available online at http://dels.nas.edu/ilar.
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From page 10...
... a description of procedures or methods designed to assure that discomfort and pain to animals will be limited to that which is unavoidable in the conduct of scientifically valuable research and that analgesic, anesthetic, and tranquilizing drugs will be used where indicated and appropriate to minimize discomfort and pain to animals; 3. a written narrative description of the methods and sources used to consider alternatives to procedures that may cause more than momentary or slight pain or distress to the animals; 4.
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From page 11...
... Availability or appropriateness of the use of less-invasive procedures, other species, isolated organ preparation, cell or tissue culture, or computer simulation. · Appropriate sedation, analgesia, and anesthesia.
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