Review of the Army's Technical Guides on Assessing and Managing Chemical Hazards to Deployed Personnel (2004) / Chapter Skim
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Appendix B: Review of Acceptable Cancer Risk Levels
Appendix B: Review of Acceptable Cancer Risk Levels
Pages 137-144
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From page 137... ...
, DOE facilities emitting radionuclides (7 × 10-4) , and uranium mill tailings emitting radon (5 × 10-4)
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From page 138... ...
The court suggests that significant occupational risk be determined by comparing the risk in question with other common occupational risks levels. The court suggested that an occupational lifetime cancer risk of 1 × 10-3 is significant.
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From page 139... ...
. TABLE B-1 Risk Considered Acceptable within OSHA Permissible Exposure Limits Chemical Residual Risk at PELs Arsenic 8 × 10-3 Ethylene oxide 1-2 × 10-3 Ethylene dibromide 0.2-6 × 10-3 Benzene 5-16 × 10-3 Acrylonitrile 39 × 10-3 Dibromochloropropane 2 × 10-3 Asbestos 6.7 × 10-3 Source: Adapted from Rodricks et al.
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From page 140... ...
) , EPA decided it would base its regulatory decisions on quantitative risk assessments using the general policy that a lifetime added cancer risk for the most exposed person of 1 in 10,000 (1 × 10-4)
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From page 141... ...
. In 1973, FDA employed quantitative risk assessment using the MantelBryan methodology for estimating cancer risks (Mantel and Bryan 1961; Rodricks et al.
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From page 142... ...
In the case of fish contaminated with PCBs, FDA considered that an estimated risk of 1 × 10-4 provided adequate protection to the public health on the basis of their PCB residue tolerance of 2 ppm. This conclusion considered the ubiquity of the contaminant and the presumed benefit from consuming fish proteins.
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From page 143... ...
but did not indicate how that level of health protection was selected. For its air quality guidelines, WHO provides only qualitative guidance by specifying that the "acceptability of the risk and, therefore, the standards selected, depends on the expected incidence and severity of the potential effects, the size of the population at risk, the perception of the related risk and the degree of scientific uncertainty that the effects will occur at a specific level of air pollution" (WHO 2000)
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From page 144... ...
WHO (World Health Organization)
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