Seeking Security Pathogens, Open Access, and Genome Databases (2004) / Chapter Skim
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1 Introduction
1 Introduction
Pages 15-20
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From page 15... ...
All those technologies allow the rapid analysis of the entire repertoire of proteins and other macromolecules produced by a cell, and they have generated very large biological databases and associated analytic software tools. Those and other advances now allow life scientists to assemble the mass of new data into an accurate and detailed way to reach the goal of understanding how organisms function.
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From page 16... ...
To reach it, scientists must gain a detailed understanding of what makes the immune response effective and of how pathogens cripple or evade the immune response to cause disease. As more details of the interplay between pathogenic microorganisms and the immune system become known, scientists will probably be able to create new and powerful strategies to fight infection, create better vaccines, and develop faster, more precise diagnostic tools (Moxon and Rappuoli, 2002; Rappuoli and Covacci, 2003)
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From page 17... ...
They called for journals to devise appropriate procedures for reviewing security risks and to encourage scientists to communicate their data in ways that minimize risk and maximize benefits. On October 8, 2003, the National Academies released a report, Biotechnology Research in an Age of Terrorism, written by the Committee on Research Standards and Practices to Prevent the Destructive Application of Biotechnology, chaired by Gerald Fink, of the Whitehead Institute in Cambridge, Massachusetts.
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From page 18... ...
The National Science Foundation, the National Institutes of Health, the Department of Homeland Security, and the Central Intelligence Agency funded the National Academies to convene a committee, to hold a workshop, and to produce a report about how biological scientists view the potential for misuse of genome sequence data and the policies governing access to databases that contain them.
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From page 19... ...
The National Academies Committee on Genomics Databases for Bioterrorism Threat Agents organized a 1-day workshop on the public release of genome data on bioterrorism-threat agents, which was held in Washington, DC, on October 1, 2003. About 40 invited scientists and policy experts who work in government, private industry, and academic laboratories attended.
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From page 20... ...
20 SEEKING SECURITY sequences of many organisms can be thought of as "raw material" for modern biological research or as the platform from which research can be launched. Data on one organism often prove to be invaluable for building a better understanding of other organisms, and data from many organisms taken together and compared, analyzed, and applied to new questions will allow new and fundamental insights into biological processes.
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