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Pages 380-385

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From page 380...
... TABLE 1 Dietary Reference Intakes for Selenium by Life Stage Group DRI values (mg/day) EARa RDAb AIc ULd Life stage groupe 0 through 6 mo 15 45 7 through 12 mo 20 60 1 through 3 y 17 20 90 4 through 8 y 23 30 150 9 through 13 y 35 40 280 14 through 18 y 45 55 400 19 through 30 y 45 55 400 31 through 50 y 45 55 400 51 through 70 y 45 55 400 > 70 y 45 55 400 Pregnancy £ 18 y 49 60 400 19 through 50 y 49 60 400 Lactation £ 18 y 59 70 400 19 through 50 y 59 70 400 a EAR = Estimated Average Requirement.
From page 381...
... PART III: SELENIUM 381 SELENIUM S elenium is an antioxidant nutrient involved in the defense against oxida tive stress. Selenoproteins regulate thyroid hormone actions and the re dox status of vitamin C and other molecules.
From page 382...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 382 selenomethionine, which is not known to have a physiological function sepa rate from that of methionine. The second reserve pool is the selenium found in liver glutathione peroxidase.
From page 383...
... PART III: SELENIUM 383 UL for selenium is based on selenosis as the adverse effect and represents total intake from food, water, and supplements. The most frequently reported features of selenosis (chronic toxicity)
From page 384...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 384 Dietary Supplements Selenium is widely available in a variety of supplements and multivitamin prepa rations. In the 1986 National Health Interview Survey (NHIS)
From page 385...
... PART III: SELENIUM 385 • Skin rash • Garlic breath odor • Fatigue • Irritability • Nervous system abnormalities Special Considerations Soil variations: There are high-selenium regions in the United States, such as western South Dakota and eastern Wyoming, but the U.S. Department of Agriculture has identified them and proscribed their use for raising animals for food.

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