Fluoride in Drinking Water A Scientific Review of EPA's Standards (2006) / Chapter Skim
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Appendix B Measures of Exposure to Fluoride in the United States: Supplementary Information
Appendix B Measures of Exposure to Fluoride in the United States: Supplementary Information
Pages 416-438
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From page 416... ...
. On the other hand, a recent news article indicates that some areas in Virginia 1See also local drinking water information by state at http://www.epa.gov/safewater/dwinfo.
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From page 417... ...
(2003) reported on fluoride concentrations in water samples collected in 1999 from 24 locations nationwide; these locations were expected to provide nationally representative samples for the National Food and Nutrient Analysis Program.2 Not unexpectedly, their findings indicate a bimodal distribution of fluoride concentrations in public drinking water: either water was fluoridated at approximately 1 mg/L or it was not fluoridated, with concentrations bordering on undetectable.
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From page 418... ...
drinking water and indirect water (water added to foods and beverages during preparation at home or by local food service establishments)
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Because these estimates were developed for the purpose of estimating people's exposures to substances in drinking water and also are based on relatively recent data,
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From page 420... ...
420 detropeR c latoT 382,45 662,543 932,71 897,414 422,108 030,1 171,7 501,929 295,52 453 255,403 050,644 332,462 256,203 515,161 998,1 012,753 316,84 221 326,421 000,4 546,401 306,341 589,28 895,53 552,52 155,72 b -- -- -- -- -- -- -- - toN nevig 574,7 -- -- 856,6 829,13 -- 855,14 998,1 -- -- -- -- -- -- -- 294 -- -- - 0 0.4 615 -- 0 629,1 0 0 0 0 0 005 005 097,5 544,1 0 0 0 522 0 0 0 0 081 418,1 0 0 0 -- 0 0 0 0 0 0 0 2991ninoitadiroulFlarutaNfoleveLybseziSnoitalupoP L/gm,ediroulFlarutaNfoleveLdetropeR 9.3-0.2 728,6 952,93 005 969,163 722,1 002,1 056,2 184,65 145,5 484,82 648,22 995,21 001 763 065,1 609,61 171,7 781,5 091,11 9.1-3.1 591,52 231,36 -- 385,42 557,57 061 0 534,73 878 0 572,8 732,19 452,63 281,09 859,41 0 787,44 507,11 0 869,9 809 569,9 861,85 329,3 253,4 826,3 947,3 2.1 863,72 903,242 -- 517,983 509,363 078 171,7 344,098 930,61 453 721,392 006,192 098,771 639,681 488,18 0 025,203 385,63 221 506,411 683,2 021,39 214,47 254,58 642,13 044,61 216,21 Reported ,egnaR L/gm 6.3-7.0 4.7-7.0 d AN 5.3-7.0 2.11-1.0 9.1-7.0 9.0-6.0 6.3-5.0 0.2-7.0 7.0 9.51-6.0 0.4-7.0 4.4-7.0 0.7-7.0 6.2-5.0 e AN 8.3-7.0 1.5-3.0 1.1-0.1 9.1-7.0 2.3-7.0 5.3-8.0 0.5-7.0 3.7-1.0 4.1-3.0 6.2-5.0 9.3-0.1 3-B ELBAT a etatS amabalA anozirA sasnakrA ainrofilaC odaroloC tucitcennoC erawaleD adirolF aigroeG iiawaH ohadI sionillI anaidnI awoI sasnaK ykcutneK anaisiuoL dnalyra sttesuhcassa nagihci atosenni ippississi iruossi anatno M M M M M M M aksarbeN adaveN erihspmaH weN
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From page 421... ...
421 544,311 584,782 612,1 106,091 124,02 557,942 710,111 568,24 599,873 857,73 593,559,2 008,01 496,642 394,26 956 058,471 249,83 955,459,9 larutan ton -- 162 635,1 670,381 -- 010,1 -- -- -- -- 002,52 -- 804 -- -- -- -- 105,103 htiwsmetsysretaw odsnmuloc on gnidecerpeht 0 592,4 0 0 397,3 0 598,81 0 816,501 296 368,63 0 627,81 0 0 0 021 898,102 detropertnomreV 156,42 655,85 0 523 420,6 054,31 669,8 086 034,091 830,14 623,332 0 429,702 619,4 0 041,05 441,2 436,424,1 054,65 916,54 0 002,7 200,6 855,401 308,02 023,2 869,72 350,41 143,624 065,2 324,11 711,3 0 075,63 489,12 561,604,1 dna,eessenneT,dnalsI 443,23 457,871 0 0 502,5 369,131 353,26 568,93 429,26 790,01 405,432,2 042,8 814,8 064,45 956 317,09 496,41 203,476,6 edohR,ainavlysnneP,enia nisrebmuneht,seicnetsisnocnilanretnitnerappafoesuaceB.etats 5.2-7.0 31-7.0 e AN 7.2-0.0 0.7-5.0 8.2-8.0 0.21-7.0 4.2-7.0 9.5-1.0 0.6-7.0 8.8-7.0 0.2-7.0 3.6-7.0 7.2-7.0 2.1 7.2-7.0 5.4-7.0 M,aibmuloCfotcirtsiD hcaerofelbat yrammuseht .3991 yesreJ ocixe M kroY weN weN weN aniloraChtroN atokaDhtroN oihO amohalkO nogerO aniloraChtuoS ni atokaDhtuoS saxeT hatU ainigriV notgnihsa ainigriVtse nisnocsi gnimoy W W W W slatoT .tnirpsimaebotdetcepsusrebmunrehtoemosro0.0sadetropeR .) atadaksalAehtfonoitacilpudadeniatnocsasnakrArofelbateht(dedivorptonerewsasnakrArofataD a eht,aksalA .noitadiroufl b c neviglatoT .latotemasehtevigylirassecen d e.ediroufllarutanhtiwsmetsysllarof0.0sadetropeR CDC:ECRUOS
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From page 422... ...
422 yb,6991-4991gniruDsecruoSytinummoC noitalupoP 576,146,242 631,260,1 896,944,1 100,439,01 236,685,11 850,743,41 898,734,41 764,537,61 720,856,71 965,977,601 211,484,91 770,761,82 367,566,811 625,191,1 070,748,81 526,329,51 245,307,28 219,579,321 803,023,1 126,020,81 047,942,51 342,583,98 750,179 565,546,1 774,152,55 elpmaS eziS 210,41 111 531 526,1 011,1 488 957 777 446 995,4 014,1 859,1 280,7 811 218,1 867 483,4 039,6 821 708,1 867 722,4 43 56 671,2 ht99 elitnecreP 372,4 663,1 925,1 783,1 589,1 999,1 465,2 368,3 653,5 537,4 222,4 866,3 616,4 182,1 137,1 489,3 939,4 368,3 485,1 410,2 895,2 862,4 890,4 844,3 793,4 morf) yad/Lm(noitsegnIreta ht59 elitnecreP 006,2 460,1 221,1 259 312,1 142,1 247,1 951,2 280,3 629,2 127,2 406,2 337,2 121,1 551,1 850,2 610,3 284,2 221,1 901,1 477,1 117,2 885,3 885,2 227,2 WyliaDegarevAdetamitsE secruoSytinummoC ht09 elitnecreP 960,2 349 059 917 049 599 514,1 966,1 571,2 623,2 792,2 091,2 461,2 188 439 376,1 783,2 500,2 769 049 283,1 561,2 959,2 448,1 440,2 ht05 elitnecreP 587 345 564 762 363 773 374 306 117 569 111,1 941,1 418 144 553 595 830,1 747 245 923 754 349 646,1 355 657 morfreta Mean 000,1 925 205 153 454 584 146 718 330,1 171,1 242,1 242,1 250,1 264 444 828 242,1 159 065 624 836 611,1 566,1 278 489 4-B WemusnoCoh .a0002 ELBAT WelpoeP noitalupoP sremusnocllA raey5.0< raey9.0-5.0 sraey3-1 sraey6-4 sraey01-7 sraey41-11 sraey91-51 sraey42-02 sraey45-52 sraey46-55 sraey56 )
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From page 423... ...
423 elpoePyb,6991-4991gniruDreta noitalupoP 608,613,75 762,835 301,654 102,235,2 378,633,2 657,808,2 398,698,2 434,825,3 612,980,5 453,784,82 875,789,3 131,556,4 293,892,62 910,575 022,557,3 059,969,2 302,899,81 414,810,13 153,914 016,229,3 773,554,3 670,122,32 803,872 546,896 834,972,61 elpmaS eziS 870,3 15 73 863 312 461 841 361 971 471,1 972 203 505,1 84 673 441 739 375,1 04 963 761 799 7 72 116 ht99 elitnecreP 613,3 391,1 875,1 571,1 913,1 767,1 291,2 941,3 621,3 687,3 938,2 845,2 187,3 793,1 586,1 208,2 558,3 130,3 103,1 743,1 341,3 060,3 682,1 891,2 390,3 WdelttoB morf) yad/Lm(noitsegnIreta ht59 elitnecreP 769,1 159 808 918 229 589 024,1 777,1 343,2 189,1 603,2 470,2 790,2 210,1 748 228,1 303,2 398,1 698 399 735,1 579,1 322,1 759,1 229,1 ht09 elitnecreP 865,1 698 208 946 497 828 990,1 305,1 046,1 377,1 338,1 667,1 626,1 508 767 324,1 477,1 245,1 598 567 611,1 747,1 441,1 019,1 895,1 ht05 elitnecreP 235 943 163 232 513 323 163 864 235 126 586 587 325 713 662 464 295 235 824 982 753 096 806 386 295 WyliaDegarevAdetamitsE Mean 737 114 734 203 093 614 835 566 687 228 068 019 947 414 563 286 548 727 634 573 445 918 947 198 667 reta 5-B ELBAT WdelttoBemusnoCoh .a0002 W noitalupoP sremusnocllA raey5.0< raey9.0-5.0 sraey3-1 sraey6-4 sraey01-7 sraey41-11 sraey91-51 sraey42-02 sraey45-52 sraey46-55 sraey56 )
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From page 424... ...
424 ) snretsiCdnaslle noitalupoP 447,396,43 444,711 936,891 894,342,1 200,283,1 238,121,2 254,342,2 248,273,2 528,908,1 457,084,51 675,405,3 088,812,4 035,088,71 928,891 256,665,2 517,110,2 433,301,31 412,318,61 452,711 086,081,2 975,406,2 107,019,11 414,281 334,861 299,957,6 elpmaS eziS 921,2 51 41 602 731 431 121 901 76 137 272 323 551,1 61 952 301 777 479 31 812 721 616 7 7 382 W,.g.e(secruoSrehtO ht99 elitnecreP 028,3 878 765 091,1 233,1 326,1 680,3 904,2 739,1 827,4 251,5 707,3 437,4 377 036,1 787,2 388,4 530,3 957 561,1 984,2 321,3 026,2 473,3 650,3 morf)
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From page 425... ...
42 sremusnoCyb6991-4991gniruDsecruoSllA noitalupoP 532,279,952 727,705,1 399,237,1 384,341,21 223,834,21 676,842,51 726,405,51 290,796,71 787,445,81 402,110,311 783,541,12 739,799,03 672,899,621 013,065,1 338,594,02 239,788,61 102,450,88 959,379,231 014,086,1 846,433,91 787,313,61 411,546,59 868,171,1 888,157,1 956,945,85 elpmaS eziS 271,51 651 451 418,1 391,1 739 218 418 876 609,4 145,1 761,2 986,7 151 399,1 908 637,4 384,7 951 159,1 718 655,4 14 07 413,2 ht99 elitnecreP 808,4 563,1 276,1 393,1 130,2 271,2 330,3 720,4 108,5 952,5 593,4 057,3 212,5 765,1 718,1 110,4 625,5 252,4 456,1 530,2 380,3 215,4 420,4 755,3 128,4 morf) yad/Lm(noitsegnIreta ht59 elitnecreP 229,2 870,1 372,1 399 862,1 524,1 269,1 414,2 236,3 733,3 999,2 807,2 941,3 872,1 452,1 434,2 425,3 307,2 131,1 622,1 559,1 829,2 767,3 476,2 259,2 ht09 elitnecreP 543,2 749 031,1 708 910,1 131,1 526,1 798,1 805,2 836,2 755,2 423,2 384,2 121,1 420,1 898,1 047,2 122,2 059 399 256,1 614,2 120,3 933,2 663,2 ht05 elitnecreP 540,1 545 365 153 864 415 156 677 310,1 372,1 873,1 543,1 070,1 835 154 167 133,1 120,1 955 544 466 122,1 894,1 822,1 560,1 WyliaDegarevAdetamitsE nae M 142,1 445 085 224 845 806 518 600,1 382,1 684,1 235,1 354,1 003,1 945 635 100,1 945,1 581,1 775 825 038 983,1 608,1 813,1 562,1 .a0002 7-B ELBAT reta Wfo noitalupoP sremusnocllA raey5.0< raey9.0-5.0 sraey3-1 sraey6-4 sraey01-7 sraey41-11 sraey91-51 sraey42-02 sraey45-52 sraey46-55 sraey56 )
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From page 426... ...
426 secruoSytinummoC noitalupoP 438,247,632 665,430,1 821,504,1 863,714,01 616,157,01 689,724,31 652,201,41 155,646,61 721,624,71 849,618,401 877,110,91 015,207,72 591,670,711 982,081,1 460,568,71 463,717,51 874,313,28 936,666,911 504,952,1 609,137,61 344,130,51 588,346,68 573,049 565,546,1 816,000,45 elpmaS eziS 395,31 601 821 845,1 520,1 028 637 177 736 215,4 383,1 729,1 539,6 511 507,1 557 063,4 856,6 911 886,1 257 990,4 33 56 621,2 morf) yaDrepthgie ht99 elitnecreP 97 042 071 211 59 06 45 26 08 56 85 35 18 532 78 76 26 77 302 89 84 36 75 74 66 WydoBfogk/Lm(noitsegnIreta secruoSytinummoC ht59 elitnecreP 44 402 721 86 56 93 63 23 93 04 83 73 34 571 55 83 83 54 961 16 23 14 55 34 93 morfreta ht09 elitnecreP 33 961 611 35 54 33 72 62 13 23 23 23 23 931 34 72 03 53 931 54 62 33 45 33 23 WyliaDegarevAdetamitsE WemusnoCoh ht05 elitnecreP 31 58 25 02 81 21 01 9 11 31 41 61 31 06 61 01 31 41 96 71 9 41 02 9 21 8-B ELBAT WelpoePyb,6991-4991gnirud Mean 71 88 65 62 32 61 31 21 51 61 71 81 61 66 12 41 51 71 27 12 21 71 62 41 51 .a0002 noitalupoP sremusnocllA raey5.0< raey9.0-5.0 sraey3-1 sraey6-4 sraey01-7 sraey41-11 sraey91-51 sraey42-02 sraey45-52 sraey46-55 sraey56 )
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From page 427... ...
42 gniruDsecruoSllA noitalupoP 886,766,352 738,564,1 324,886,1 542,306,11 278,655,11 406,923,41 192,611,51 205,465,71 425,422,81 918,839,011 102,646,02 073,335,03 255,662,521 012,835,1 315,084,91 156,246,61 871,506,78 631,104,821 050,616,1 802,900,81 241,830,61 637,737,29 681,141,1 749,927,1 709,461,75 elpmaS eziS 627,41 941 741 237,1 301,1 378 687 608 866 318,4 315,1 631,2 235,7 741 288,1 497 907,4 491,7 941 628,1 897 124,4 04 96 852,2 morf) yaDrepthgie ht99 elitnecreP 78 932 581 811 79 07 06 66 68 96 95 45 68 332 19 96 76 88 002 401 65 96 07 16 77 WydoBfogk/Lm(noitsegnIreta ht59 elitnecreP 05 691 461 47 86 44 04 83 44 64 24 93 94 371 26 24 34 05 071 66 63 54 75 44 64 ht09 elitnecreP 83 961 021 06 15 63 33 92 43 73 53 43 83 461 84 23 43 93 851 05 92 73 35 93 63 ht05 elitnecreP 71 78 85 62 32 71 41 21 41 71 81 91 61 66 02 31 61 81 27 12 31 81 52 91 61 WyliaDegarevAdetamitsE reta 9-B ELBAT WfosremusnoCyb6991-4991 Mean 12 29 56 13 72 02 61 51 81 02 02 12 02 77 52 61 91 22 97 62 51 12 82 12 02 .a0002 noitalupoP sremusnocllA raey5.0< raey9.0-5.0 sraey3-1 sraey6-4 sraey01-7 sraey41-11 sraey91-51 sraey42-02 sraey45-52 sraey46-55 sraey56 )
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From page 428... ...
. For the intake values shown in Table B-10, approximately 80% of the intake comes from drinking water and other beverages (including caffeinated and alcoholic beverages)
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From page 429... ...
APPENDIX B 42 TABLE B-10 Adequate Intake Values (L/day) for Total Water Males Females From From Total From From Total Group Foods Beverages Water Foods Beverages Water 0-6 months 0 0.7 0.7 0 0.7 0.7 7-12 months 0.2 0.6 0.8 0.2 0.6 0.8 1-3 years 0.4 0.9 1.3 0.4 0.9 1.3 4-8 years 0.5 1.2 1.7 0.5 1.2 1.7 9-13 years 0.6 1.8 2.4 0.5 1.6 2.1 14-18 years 0.7 2.6 3.3 0.5 1.8 2.3 >19 years 0.7 3.0 3.7 0.5 2.2 2.7 Pregnancya -- -- -- 0.7 2.3 3.0 Lactationa -- -- -- 0.7 3.1 3.8 aWomen aged 14-50 years.
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From page 430... ...
. exPosures From Fluorinated anesthetiCs The sampled data in Table B-15 illustrate wide ranges of reported mean peak serum fluoride concentrations from the use of fluorinated anesthetics under various surgical conditions and for different age groups ranging from 22-day-old infants to people > 70 years old.
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From page 431... ...
APPENDIX B 431 TABLE B-12 Estimated Intake of Fluoride from Community Water for 90th Percentile Consumersa Fluoride Level Water Intake, 0.7 mg/L 1 mg/L 1.2 mg/L 2 mg/L 4 mg/L Population mL/day Intake, mg/day All consumers 2,069 1.45 2.07 2.48 4.14 8.28 <0.5 year 943 0.66 0.94 1.13 1.89 3.77 0.5-0.9 year 950 0.67 0.95 1.14 1.90 3.80 1-3 years 719 0.50 0.72 0.86 1.44 2.88 4-6 years 940 0.66 0.94 1.13 1.88 3.76 7-10 years 995 0.70 1.00 1.19 1.99 3.98 11-14 years 1,415 0.99 1.42 1.70 2.83 5.66 15-19 years 1,669 1.17 1.67 2.00 3.34 6.68 20-24 years 2,175 1.52 2.18 2.61 4.35 8.70 25-54 years 2,326 1.63 2.33 2.79 4.65 9.30 55-64 years 2,297 1.61 2.30 2.76 4.59 9.19 65 years 2,190 1.53 2.19 2.63 4.38 8.76 Water Intake, mL/kg/day Intake, mg per kg body weight/day All consumers 33 0.023 0.033 0.040 0.066 0.132 <0.5 year 169 0.118 0.169 0.203 0.338 0.676 0.5-0.9 year 116 0.081 0.116 0.139 0.232 0.464 1-3 years 53 0.037 0.053 0.064 0.106 0.212 4-6 years 45 0.032 0.045 0.054 0.090 0.180 7-10 years 33 0.023 0.033 0.040 0.066 0.132 11-14 years 27 0.019 0.027 0.032 0.054 0.108 15-19 years 26 0.018 0.026 0.031 0.052 0.104 20-24 years 31 0.022 0.031 0.037 0.062 0.124 25-54 years 32 0.022 0.032 0.038 0.064 0.128 55-64 years 32 0.022 0.032 0.038 0.064 0.128 65 years 32 0.022 0.032 0.038 0.064 0.128 aBased on water consumption rates estimated by EPA (2000a)
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From page 432... ...
None of the studies presented in Table B-15 shows clear evidence of renal impairment as a result of the increased serum fluoride concentration, except transient reduction in renal function among the elderly (>70 years) reported by Hase et al.
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From page 433... ...
. Because the reference point for the potential nephrotoxicity in these studies was the peak serum fluoride concentration, data are generally not available for an estimation of the total fluoride load or the area under the curve from the use of these anesthetics.
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From page 434... ...
434 secnerefeR 8991.latearaH 9991.lateeniduorG 0002.lateesaH 6991.lategrebdloG 4991.latenamweN 5991.lateihcugiH 9891.lateduobbA 9891.lateduobbA 0002.lateatabO 4991.latearumusta M 6991.lateenrobsO 2991.lateyarru 9891ajotere 9891ajotere 9891ajotere 9891ajotere 9891ajotere 9891ajotere 9891ajotere 9891ajotere M MdnanenokkiO MdnanenokkiO MdnanenokkiO MdnanenokkiO MdnanenokkiO MdnanenokkiO MdnanenokkiO MdnanenokkiO 9891elkniH 8791iroakaTdnaiakaS 5991.lateneznoC 3002.lateimlasiaL stnegAcitehtsenAdetaniroulF cinagronI kaeP egnahcoN 3 4 5 4.5 5.5 6.5 6.5 4.7 8 9.72-4.8 2.34 8-2 01-4 01-6 3 7 11 11 7 5.01 7 3.31 8.31 mureSnae M Mm,ediroulF enilesaB AN AN AN 5.2tuoba 8.3 2< 6.5 9.5 AN AN 4.2-1.2 8.3-5.3 AN AN AN AN AN AN AN AN 7.1 3-2tuoba AN AN morfnoitartnecnoCediroulFcinagronI a ruoh-CA AN AN c M 7.3 AN 1.1 2.9 60.0 41.0 9.51 8.4 AN 2.91 7.0-3.0 5.1-7.0 3.3-5.1 6.0 5.1 6.1 6.1 0.2 AN 8.6-4 70.1 1 stcejbuSfo.oN 31 09 6 62 42 11 02 02 02 7 5 9 04 1 1 1 1 1 8 5 02 61 mureS 51-B ELBAT ) egnar(egA enaruflosI sraey15 AN sraey07> sraey5.55 b sraey75 sraey82 b sraey82 sraey7.72 sraey5.84 sraey7.35 sraey45-62 sraey57-02 enaruflnE sraey11otsyad22 yad22 yad92 shtnom3 shtnom4 shtnom9 sraey9-1 sraey06-74 sraey9.36 )
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From page 435... ...
43 3002.lateimlasiaL 5991.lateocnalB 7891.latesnisuoC 6791.latesnisuoC 5991.lateyadnu 5991.lateyadnu M M 6791.latesnisuoC 5991.laterenraS 8791iroakaTdnaiakaS 7891.latesnisuoC 9891.lateduobbA 4991.lateneniaviaT 1992 al. et Murray 2002.latesujeL 5991.laterenraS 0002.lateesaH 4991.lateneniaviaT 4991.latenamweN 5991.lateneznoC 5991.lateocnalB 6991.lategrebdloG 5991.lateyadnu M 5991.lateihcugiH 8991.lataaraH 9991.lateeniduorG deunitnoc 7.81 57.61 81 2.22 1.82 5.72 6.1 8.1 3 4 6.5 6 12.6 8.31 7.41 81 12 32 52 7.72 82 5.03 43-13 6.63 8.63 13tuoba 04 AN 2.1 5.2-2 8.1 AN 9.1 AN 3-2 5.2-2 9.5 AN 3.8 AN AN AN AN 8.3 AN 2.1 5.2tuoba AN 2< AN AN 1 8.2 42.1 7.2 6 9.4 6.2 9.4-9.2 5.2 70.0 2.2 19.5 7.4 6.2 1.5 2.2 8.0 10.1 9.2 AN 3 6 9 9.9 7.3 9.2 71 04 8 01 5 5 01 04 5 8 02 52 10 14 04 7 52 52 12 04 42 5 5 5 51 31 89 d )
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From page 436... ...
436 sa secnerefeR 4991.lateihcugiH 0002.lateatabO 0002.lateatabO 4991.latearumusta M 5991.lateihcugiH detamitsesiti,detropertonsirh-CA M cinagronI kaeP 9.14 1.74 5.35 45 5.75 neh mureSnae M Mm,ediroulF enilesaB AN AN AN AN 2< a ruoh-CA M 6.01 woflhgih0.81 wofl .enaruflosi wol7.61 W.noitartnecnoccitehtsenaladit-dne 1.6 0.41 stcejbuSfo.oN 11 01 01 8 8 deunitnoC naemehtro,noitartnecnocraloevla 51-B ELBAT ) egnar(egA )
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From page 437... ...
APPENDIX B 43 TABLE B-16 Summary of Estimated Safe and Adequate Daily Dietary Intakesa of Fluoride Age, years Weight, kgb Range, mg/day Range, mg/kg/dayc 0-0.5 6 0.1 0.5 0.017 0.083 0.5-1 9 0.2 1.0 0.022 0.11 1-3 13 0.5 1.5 0.038 0.12 4-6 20 1.0 2.5 0.050 0.13 7-10 28 1.5 2.5 0.054 0.089 Males 11-14 45 1.5 2.5 0.033 0.056 15-18 66 1.5 2.5d 0.023 0.038 19-24 72 1.5 4.0e 0.021 0.056 25-50 79 1.5 4.0 0.019 0.051 51+ 77 1.5 4.0 0.019 0.052 Females 11-14 46 1.5 2.5 0.033 0.054 15-18 55 1.5 2.5d 0.027 0.045 19-24 58 1.5 4.0e 0.026 0.069 25-50 63 1.5 4.0 0.024 0.063 51+ 65 1.5 4.0 0.023 0.062 aThe term "safe and adequate daily dietary intake" was used by the NRC (1989b) "when data were sufficient to estimate a range of requirements, but insufficient for developing [a Recommended Dietary Allowance]
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From page 438... ...
438 APPENDIX B TABLE B-17 Summary of Dietary Reference Intakes of Fluoride Reference Adequate Intake Tolerable Upper Intake Age, years Weight, kg mg/d mg/kg/daya mg/d mg/kg/daya 0-0.5 7 0.01 0.0014 0.7 0.10 0.5-1 9 0.5 0.056 0.9 0.10 1-3 13 0.7 0.054 1.3 0.10 4-8 22 1 0.045 2.2 0.10 9-13 40 2 0.050 10 0.25 Boys 14-18 64 3 0.047 10 0.16 Girls 14-18 57 3 0.053 10 0.18 Males 19+ 76 4 0.053 10 0.13 Females 19+ 61 3 0.049 10 0.16 aCalculated from intake (mg/day) and weight (kg)
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