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Section II Recommendations
Pages 255-258

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From page 255...
... Funding agencies should be committed to sustained and vigorous support for research on the etiologies of preterm birth to fill critical knowledge gaps. Areas to be supported should include the following: • The physiological and pathologic mechanisms of parturition across the entire gestational period as well as the pregestational period should be studied.
From page 256...
... The committee acknowledges that with each additional potential interaction sought, the sample size required to retain an adequate statistical power to reveal meaningful differences increases. Recommendation II-2: Study multiple risk factors to facilitate the modeling of the complex interactions associated with preterm birth.
From page 257...
... The National Institutes of Health and other agencies, such as the Cen ters for Disease Control and Prevention and the Agency for Healthcare Research and Quality, should provide support for re searchers to conduct investigations to obtain an understanding of the mechanisms by which fertility treatments, such as assisted re productive technologies and ovulation promotion, may increase the risk for preterm birth. Studies should also be conducted to investi gate the outcomes for mothers who have received fertility treat ments and who deliver preterm and the outcomes for their infants.
From page 258...
... • Conduct basic biological research to identify the mechanisms of preterm birth relevant to fertility treatments and the underlying causes of infertility or subfertility that may contribute to preterm delivery. • Investigate the outcomes for preterm infants as well as all infants whose mothers received fertility treatments.


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