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Asbestos Selected Cancers (2006) / Chapter Skim
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1 Introduction
Pages 13-17

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From page 13...
... Based on its examination and evaluation of the extant literature and other information it may obtain in the course of the study, the committee will determine if there is a causal association between asbestos and colorectal, laryngeal, esophageal, pharyngeal, or stomach cancers. CURRENT LEGISLATION The committee's charge to determine whether asbestos may play a causal role in the occurrence of cancer at the five specified sites was drawn directly from Senate Bill 852, the Fairness in Asbestos Injury Resolution (FAIR)
From page 14...
... People who have a diagnosis of asbestosis, lung cancer, or mesothelioma will be eligible to file a claim documenting their asbestos exposure. Eligibility may also be extended to any additional cancers that are found to be causally associated with asbestos by the report of the present IOM expert committee delineated as item (e)
From page 15...
... Complementary information on these cancer sites was reported from studies that assessed site-specific cancer risk in relation to occupational exposures in general; asbestos exposure was specifically addressed in many of these case-control studies. The epidemiologic information is further complemented by an extensive toxicologic literature that includes animal bioassays and investigation of mechanisms of disease production.
From page 16...
... Because the committee's charge requires a determination of whether asbestos "causes" cancer at the specific sites, the committee considered various guidelines for causal inference and the terminology for classifying the strength of evidence in support of causation. That review led to the application of guidelines for causal inference based on the widely applied criteria proposed by Hill (1965)
From page 17...
... Geological Society of America Special Paper 373: 447-470. Virta RL.


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