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Asbestos Selected Cancers (2006) / Chapter Skim
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10 Stomach Cancer and Asbestos
Pages 203-215

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From page 203...
... In the United States, the incidence per 100,000 people varies markedly by race and ethnicity: the incidence in Asian and Pacific islanders is 23.0 and 12.8 in males and females, respectively; in blacks, 19.9 and 9.9; in Hispanics, 18.1 and 10.0; in American Indians and Alaska natives, 14.4 and 8.3; and in white non-Hispanics, 10.0 and 4.3. The age-standardized death rate from stomach cancer has declined on average by 2.5-3.0% per year since 1975.
From page 204...
... Their histories and design properties are described in Table B.1, and the details of their results concerning cancer at this site are abstracted in Table D.4. The results of the cohort and casecontrol studies are summarized in Table 10.1, and Figures 10.1 and 10.2 are plots of RRs for overall exposures and for exposure-response gradients from the cohort studies reviewed.
From page 205...
... . b For studies that reported dose-response relationship on multiple gradient metrics, the smallest "high vs none" RR was used to compute the lower bound, and the largest "high vs none" RR was used in computing the upper bound.
From page 206...
... Zhu93 (men + women) Summary 95% Interval 0.01 0.1 0.25 0.5 1 2 3 5 7 10 Relative Risk FIGURE 10.1 Cohort studies: RR of stomach cancer in people with "any" exposure to asbestos compared with people who report none.
From page 207...
... Summary 95% Interval (using smallest RR) 0.01 0.1 0.25 0.5 1 2 3 5 7 10 Relative Risk FIGURE 10.2 Cohort studies: RRs of stomach cancer among people in most extreme exposure category compared to those with none ( = more than one exposure gradient reported in citation, so the plot contains both highest and lowest estimates of risk for most extreme category over all gradients)
From page 208...
... Krstev05 (women) Summary 95% Interval 0.01 0.1 0.25 0.5 1 2 3 5 7 10 Relative Risk FIGURE 10.3 Case-control studies: RR of stomach cancer in people with "any" exposure to asbestos compared with people with none.
From page 209...
... Hillerdal80 (men) Summary 95% Interval 0.01 0.1 0.25 0.5 1 2 3 5 7 10 Relative Risk FIGURE 10.4 Case-control studies: RR of stomach cancer in people with "any" exposure to asbestos compared with people with none, stratified on quality of exposure assessment (top, EAM = 1: higher-quality exposure assessment; bottom, EAM = 2: lower-quality exposure assessment)
From page 210...
... Parent98 (amphibole, men) Summary 95% Interval 0.01 0.1 0.25 0.5 1 2 3 5 7 10 Relative Risk FIGURE 10.5 Case-control studies: RRs of stomach cancer among people in with extreme exposure compared with those with none.
From page 211...
... There were also several instances in which reasonably strong dose-response gradients were observed in the occupational cohort studies. In contrast, the results from case-control studies were inconsistent, with no clear pattern emerging from the estimated risks of stomach cancer associated with asbestos exposure.
From page 212...
... The committee concluded that evidence is suggestive but not sufficient to infer a causal relationship between asbestos exposure and stomach cancer. REFERENCES Acheson ED, Gardner MJ, Pippard EC, Grime LP.
From page 213...
... : 241-248. de Klerk NH, Armstrong BK, Musk AW, Hobbs MS.
From page 214...
... British Journal of Industrial Medicine 43(3)
From page 215...
... 1979. Mortality experience of insulation workers in the United States and Canada, 1943-1976.


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