Assessing the Human Health Risks of Trichloroethylene Key Scientific Issues (2006) / Chapter Skim
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Appendix D Exposure Anaylsis of Selected Studies
Appendix D Exposure Anaylsis of Selected Studies
Pages 406-417
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. This is especially important because there are often studies of exposure in an industry, geographic area, or community that can be used together to better understand the nature of exposures during the epidemiologic studies.
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APPENDIX D 40 and hand cleaning in some areas during 1955-1968. The investigators determined that 32% had "frequent" exposures to peak concentrations (one or two daily peaks of about 15 minutes to trichloroethylene at 200-600 parts per million [ppm]
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408 APPENDIX D of exposure based on the judgment of long-term employees. No details were provided on the protocol for processing the jobs in the work histories into job classifications; no examples were provided.
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APPENDIX D 40 TCA: trichloroethylene (mg/m3)
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410 APPENDIX D maximum values were generally less than 400 ppm. The duration of exposure was uncertain.
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APPENDIX D 411 Conclusion: This study had a small cohort drawn from a wide variety of industries, predominantly degreasing and metal cleaning, who had generally low exposures (most less than 20 ppm)
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412 APPENDIX D Henschler et al.
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(2003) applied the CAREX database information developed by the International Agency for Research on Cancer and the British JEM develop by Pannett et al.
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414 APPENDIX D TABLE D-1 Trichloroethylene Exposure Summary for the Arnsberg Area Studies Long-Term Study Peak Exposures Exposures Notes Henschler >2,000 ppm, machine cleaning with 100 ppm Cherrie et al.
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APPENDIX D 41 dip tanks, extensive use of trichloroethylene for all types of cleaning, and the process descriptions. Conclusion: These workers had substantial, sustained exposures to high concentrations of trichloroethylene at 400-600 ppm during hot dip cleaning and greater than 100 ppm overall.
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416 APPENDIX D In an attempt to avoid reporting biases associated with the legal proceeding for compensation, analyses were conducted on self-reported exposure to selected agents (yes or no)
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APPENDIX D 41 Conclusion: While this case-control study includes the Arnsberg area, sev eral other regions are included as well, where the source of the trichloroethylene and chlorinated solvent exposures are much less well defined. As a result, most subjects identified as exposed to trichloroethylene probably had minimal contact, averaging concen trations of about 10 ppm or less.
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