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Amyotrophic Lateral Sclerosis in Veterans Review of the Scientific Literature (2006) / Chapter Skim
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B Possible Conceptual Models Linking Military Service and Amyotrophic Lateral Sclerosis
Pages 53-54

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From page 53...
... Involvement in military service, some sports, and some occupations may expose people to specific environmental exposures or to strenuous physical activity. These factors might act in conjunction with a genetic susceptibility inherited by some people from their parents.
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From page 54...
... 54 AMYOTROPHIC LATERAL SCLEROSIS IN VETERANS FIGURE B.1 Possible Conceptual Models Military Oxidative service Specific stress, environmental glutamate ALS Some sports exposure excitotoxicity, or or other occupations mechanism A Military Oxidative service Strenuous stress, physical ALS glutamate Some sports activity excitotoxicity, or or other occupations mechanism B Oxidative Susceptibility stress, gene variants or other ALS glutamate risk factors excitotoxicity, or other mechanism Specific environmental exposure or strenuous physical activity Military Some sports or service occupations C
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Key Terms

  • strenuous physical
  • physical activity
  • expose people
  • specific environmental
  • neuronal damage

  • damage leading
  • common step
  • involving strenuous
  • events involving
  • environmental exposures

  • environmental exposure
  • environmental agents
  • involving specific
  • genetic susceptibility
  • geneenvironment interactions

  • joint occurrence
  • including infectious
  • susceptibility inherited


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