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13 Wrap-Up Session
Pages 165-178

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From page 165...
... and a cochairperson of the Federal Dietary Reference Intakes (DRIs) Research Synthesis Subcommittee; Dr.
From page 166...
... Since the methods to study nutrient requirements in adults typically have involved invasive techniques, studies of children pose difficul ties. Therefore, addressing the requirements of infants and chil dren will require much more thought in the future.
From page 167...
... Follow-up activities after this workshop involve the database, a report, and funding. BOX 13-1 Goals of the DRI Research Synthesis Project and Progress Made DRI Research Synthesis Goals Progress Made Identify DRI research gaps.
From page 168...
... For example, this workshop and the database are very timely for the ARS, which does considerable research on human nutrient requirements. Planning for the next 5-year research cycle for the ARS Human Nutrition Program starts in January 2007.
From page 169...
... Kretsch acknowledged the efforts of the members of the Workshop Planning Committee, the Federal DRI Research Synthesis Subcommittee and its Canadian counterparts, and the federal sponsors who provided funding for this project. COMMENTS BY HASAN HUTCHINSON This presentation included a review of objectives for the DRI Research Synthesis, types of knowledge gaps in general and for Canada, and selected uses of the DRI Research Synthesis in Canada.
From page 170...
... Knowledge Gap Themes Dr. Hutchinson highlighted the following knowledge gap themes: • Requirements of children, pregnant and lactating women, and the elderly -- all of which are vulnerable population groups • Individual variation of requirements caused by genetics/epi genetics, lifestyle, environment, and geography • The need for biomarkers that are able to predict functional out comes and chronic diseases • The need to improve dietary assessments and planning methods, including survey methodology and the food composition tables and databases • Bioavailability • Interactions among nutrients Research gaps that are especially important in Canada include information on how geographical variables affect the vitamin D needs of Canadians, vitamin B12 requirements of the elderly and how they can be met (Canada has no vitamin B12 fortification of foods)
From page 171...
... , recommended dietary allowance (RDA) , and an upper safe range of intake • Substances to be included: essential nutrients and what was called "important food components" • The incorporation of aspects from the report Dietary Reference Values for Food Energy and Nutrients for the United Kingdom (COMA, 1991)
From page 172...
... This matter merits much consideration. Key Questions Relative to Research Priorities Based on the presentations and discussions of the DRI Research Synthesis Workshop, addressing the following key questions would help to define what the priorities should be for research to be undertaken immediately.
From page 173...
... , • plan the content of future dietary surveys with an eye toward the future needs for the DRIs, and • develop the food composition analytical methods and data that are essential in establishing DRI values. Incentives or disincentives for private sector research merit some consideration.
From page 174...
... In addition, it briefly covered biomarkers for foods, ethical issues, and a systematic approach for setting ULs. In his opening remarks, Dr.
From page 175...
... At the time the recommendation was made to fortify grains with folic acid, for example, the epigenetic effects of methyl donors were unknown and did not enter the discussion at all. Another approach to generate interest is to build on the experience of the clinical pharmacology specialty and to develop a new specialty called clinical nutricology.
From page 176...
... Citing a specific example related to research relevant to ULs for amino acids, Dr. Bier indicated that, despite being given specific instructions on information needs for a symposium on amino acid science, only a small proportion of the invited scientists provided information on why they need to do specific studies.
From page 177...
... Dr. Zeisel would like the DRI process to consider
From page 178...
... The Food Assistance and Nutrition Research Program of the ERS and grants programs in some other agencies support research of this type.


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