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Acute Exposure Guideline Levels for Selected Airborne Chemicals Volume 5 (2007) / Chapter Skim
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Introduction
Pages 1-8

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From page 1...
... Environmental Protection Agency (EPA) identify extremely hazardous substances (EHSs)
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From page 2...
... , children, the elderly, and persons with diseases, such as asthma, or heart disease. The National Research Council (NRC)
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From page 3...
... of a substance above which it is predicted that the general population, including susceptible individuals, could experience lifethreatening adverse health effects or death. Airborne concentrations below AEGL-1 represent exposure levels that can produce mild and progressively increasing but transient and nondisabling odor, taste, and sensory irritation or certain asymptomatic, nonsensory adverse effects.
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From page 4...
... Toxicity data from human studies are most applicable and are used when available in preference to data from animal studies and in vitro studies. Toxicity data from inhalation exposures are most useful for setting AEGLs for airborne chemicals because inhalation is the most likely route of exposure and because extrapolation of data from other routes would lead to additional uncertainty in the AEGL estimate.
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From page 5...
... The committee has expertise in toxicology, epidemiology, occupational health, pharmacology, medicine, pharmacokinetics, industrial hygiene, and risk assessment. The AEGL draft reports are initially prepared by ad hoc AEGL Development Teams consisting of a chemical manager, two chemical reviewers, and a staff scientist of the NAC contractor -- Oak Ridge National Laboratory.
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From page 6...
... Washington, DC: National Academy Press. NRC (National Research Council)
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From page 7...
... Washington, DC: National Academy Press. NRC (National Research Council)
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Key Terms

  • acute exposure
  • exposure guideline
  • guideline levels
  • exposure levels
  • hazardous substances

  • selected airborne
  • airborne chemicals
  • exposure guidance
  • including susceptible
  • community emergency

  • developing community
  • continuous exposure
  • exposure limits
  • nrc guideline
  • guideline reports

  • airborne concentration
  • airborne contaminants
  • guidance levels
  • spacecraft maximum
  • maximum allowable

  • guidance level
  • susceptible individuals
  • allowable concentrations
  • developing emergency
  • emergency exposures

  • series acute
  • nrc assigned
  • standing operating
  • susceptible subpopulations
  • represent threshold


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