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Review of the Toxicologic and Radiologic Risks to Military Personnel from Exposures to Depleted Uranium During and After Combat (2008) / Chapter Skim
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Appendix B: Risk of Selected Cancers and Nonmalignant Diseases in Uranium Workers
Pages 146-154

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From page 146...
... (2004) observed no statistically significant excess of cancer mortality overall or related to any specific site of interest.
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From page 147...
... facility was fed to the beta stage of the process. Before late 1945, uranium trioxide was received from Mallinckrodt Chemical Works and converted to uranium tetrachloride, but thereafter exposure to the insoluble oxides was partly replaced by exposure to the more soluble uranium hexafluoride and uranyl fluoride.
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From page 148...
... There were no statistically significant increases in risk of total cancer, lung cancer, bone cancer, renal cancer, lymphoma, or leukemia, nor was there an excess of chronic renal disease or other diseases. Cookfair et al.
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From page 149...
... , a nominal deficit of lung cancer (SMR, 0.78) , and a statistically significant deficit of circulatory diseases (SMR, 0.40; 95% CI, 0.2-0.8)
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From page 150...
... Radiation doses from both external and internal radiation sources were obtained; 33% of the cohort was estimated to have cumulative internal lung doses exceeding 50 mSv; only 9% of the cohort was estimated to have external doses exceedeing that level. Many workers also had exposure to solvents, especially trichloroethylene, and cutting oils; there was also exposure to tributyl phosphate, ammonium hydroxide, and hydrogen fluoride.
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From page 151...
... No information was provided on subgroups with exposure to uranium or other specific agents, so this study provides little information on the health effects of uranium exposure. LINDE AIR PRODUCTS From 1943 to 1949, the Linde Air Products Ceramics Plant near Buffalo, New York, was a uranium-processing facility.
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From page 152...
... Their cancer incidence showed no statistically significant increases in risk. There was a statistically significant excess of nonmalignant respiratory diseases, but it was based on small numbers.
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From page 153...
... . Of nonmalignant diseases, there was a nominal but not statistically significant excess of chronic renal failure (4 cases observed, 2.2 expected)
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From page 154...
... The men had worked in the industry for an average of 9 y and were followed for mortality for a median of 22 y. The findings were unremarkable with two exceptions: there were statistically significant deficits of hepatic cancer and lymphoma, but there was an excess of lung cancer (SMR, 1.18; CI, 1.1-1.3)
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Key Terms

  • uranium exposure
  • chronic renal
  • uranium hexafluoride
  • renal cancer
  • renal disease

  • lung cancers
  • nuclear fuels
  • significant excess
  • uranium tetrafluoride
  • soluble uranium

  • uranium compounds
  • uranium metal
  • insoluble uranium
  • british nuclear
  • colorado plateau

  • included exposure
  • external radiation
  • cancer incidence
  • renal failure
  • internal exposures

  • plant included
  • nonmalignant respiratory
  • uranium mills
  • uranium trioxide
  • uranium dust

  • uranium oxide
  • respiratory disease
  • uranyl fluoride
  • capenhurst plant
  • nuclear corporation


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